All Antimicrobial Resistance articles – Page 12
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NewsNovel insights into Candida glabrata in pregnant women’s reproductive tracts in Hainan
A study of Candida glabrata in pregnant women with vaginal discomfort at Haikou Maternal and Child Health Hospital found that 64.5% of the 594 yeast isolates (383 isolates) showed resistance (R) or intermediate (I) phenotypes to at least one of four commonly used antifungals.
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NewsBacterial ‘jumping genes’ can target and control chromosome ends
Researchers have discovered a new mechanism that transposons, or “jumping genes” use to survive and propagate in bacteria with linear DNA, with applications in biotechnology and drug development.
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NewsA 'Trojan Horse' approach to develop new antimalarial drugs
Researchers have discovered a key process whereby malarial parasites take up a human blood cell enzyme, which could provide a new approach for antimalarial treatment.
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NewsCentauri Therapeutics selects first clinical candidate for immunotherapeutic treatment of Gram-negative bacterial infections
Centauri Therapeutics Limited has announced the selection of its first clinical candidate in the ABX-01 programme. The compound is designed to target serious Gram-negative bacterial infections in the lung.
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NewsStudy uncovers the core principles of low-resistance antibiotics
Researchers have demonstrated that a dual-target approach, combining membrane disruption with an additional critical cellular pathway, significantly prevents the development of resistance in bacteria.
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NewsResearchers develop enhanced method for wastewater surveillance of antibiotic resistance
To better monitor the emergence and spread of antibiotic resistance, researchers have developed a CRISPR-enriched metagenomics method for the enhanced surveillance of antibiotic resistance genes, ARGs, in wastewater.
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NewsReactive nitrogen species dominance is key in the fight against antimicrobial resistance
The balance between two types of molecules – reactive nitrogen species (RNS) and reactive oxygen species (ROS) – plays a crucial role in tackling drug-resistant bacteria, according to a new study.
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NewsSuperbugs in our food: a new hope for tackling drug resistance
Researchers highlight the potential of quorum sensing inhibitors (QSIs) as a novel approach to tackle Pseudomonas aeruginosa. The study explores the mechanisms of action of various QSIs and potential applications in food safety and healthcare.
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NewsNew paper-based device boosts HIV test accuracy from dried blood samples
Scientists have trialled a more precise medical device to measure HIV viral loads by engineering a paper device with wax-printed patterns that create precise channels and collection spots, ensuring it consistently collects the same volume of blood.
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NewsScientists invent new drug candidates to treat antibiotic-resistant bacteria
Researchers designed a new family of antibiotics that’s a variation of an existing drug called vancomycin, which is used as a last resort for extremely ill patients. The new version of vancomycin targets, bonds to and renders inactive two different parts of a molecule on the surfaces of pathogenic bacteria.
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NewsScientists uncover how bacterial resistance to synergistic drug treatments is arising
Scientists investigating the potential of combined and more powerful drug treatments have found that antimicrobial resistance to these is arising via the vitamin B2 synthesis pathway.
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NewsNo more antibiotics? Scientists pioneer a safer way to protect cultured meat
A new study explores the use of Random Antimicrobial Peptide Mixtures (RPMs) as a safe and effective alternative to antibiotics in cultured meat production. These synthetic peptide cocktails eliminate bacterial contamination without harming stem cell viability or contributing to antibiotic resistance.
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NewsUsing population-level characteristics for the surveillance of antimicrobial-resistant gonorrhea
As the antimicrobial-resistant (AMR) gonorrhea poses a major threat to public health, there is an urgent need for expanding the surveillance of its prevalance to control the spread of the pathogen, through monitoring its association with the population density and HIV prevalence in cities.
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NewsInternational team publishes guideline on how to manage fungal infections caused by Candida
The new global guideline for the diagnosis and treatment of Candida infections establishes new standards for managing fungal infections, which affect millions of people worldwide every year.
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NewsDangerous bacteria lurk in hospital sink drains, despite rigorous cleaning
Even in modern hospitals, drains can serve as reservoirs for known and novel pathogens, according to a new study.
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FeaturesHow phage therapy supports One Health in the AMR fight
In the face of an escalating global health crisis, One Health demonstrates the power of collaborative, multidisciplinary action.
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NewsDiabetes can drive the evolution of antibiotic resistance, study reveals
A new study shows that people with diabetes are more likely to develop antibiotic-resistant strains of Staph. The results show how the diabetic microbial environment produces resistant mutations, while hinting at ways antibiotic resistance can be combatted in this patient population.
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NewsHarvard Pilgrim Health Care Institute announces launch of Center for Sepsis Epidemiology and Prevention Studies (SEPSIS)
The new Center for Sepsis Epidemiology and Prevention Studies (SEPSIS) is a pioneering center of excellence dedicated to advancing understanding, prevention, and management of sepsis, a life-threatening condition caused by a dysregulated immune response to infection.
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CareersHow frontline innovation from military labs can fight antimicrobial resistance worldwide
CEO at Presymptom Health, Dr. Iain Miller reveals how research in military laboratories - born out of battlefield demands - is now yielding innovative tech that allows for faster and more accurate detection of infections, even before symptoms appear.
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NewsStudents tackle drug resistance by teaching machine learning
Researchers using machine learning to predict drug resistance in patients have published a step-by-step machine learning tutorial for beginners.