All Antimicrobial Resistance articles – Page 8
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CRISPR is promising to tackle antimicrobial resistance - but remember bacteria can fight back
Experts are looking to use the Nobel winning technology to target resistance genes and make bacteria sensitive to first line antibiotics again; but the bacteria have ways to fight back.
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Antibiotic use in patients hospitalised with COVID-19 appears to have no beneficial effect on clinical outcomes
An analysis of more than 1,300 German adults hospitalised with moderate COVID-19 finds treatment with antibiotics was associated with five times greater likelihood of COVID-19 deterioration compared to patients not given antibiotics.
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Antimicrobial-resistant hospital infections remain at least 12% above pre-pandemic levels, major US study finds
Despite progress in combating antimicrobial resistance (AMR) in the USA since its peak during the COVID-19 pandemic, hospital-acquired AMR infections remain well above pre-pandemic levels, according to a major new study examining AMR before, during, and after the COVID-19 pandemic in 120 US hospitals. Source: NIAID Colorized scanning ...
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Experts call for global genetic warning system to combat the next pandemic and antimicrobial resistance
Clinical and public health microbiologists have called for investment in technology, capacity, expertise, and collaboration to put genomic surveillance of pathogens at the forefront of future pandemic preparedness.
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Study finds artificial intelligence can develop treatments to prevent superbugs
Researchers developed an AI model that can determine the best combination and timeline to use when prescribing drugs to treat a bacterial infection, based solely on how quickly the bacteria grow given certain perturbations.
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Climate change is multiplying the threat caused by antimicrobial resistance
Climate change is multiplying the threat caused by antimicrobial resistance (AMR), amplifying its growing risk through increasing global temperatures, greenhouse gas emissions and rising sea levels, experts have warned.
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Major genetic meta-analysis reveals how antibiotic resistance in babies varies according to mode of birth, prematurity, and where they live
Meta-analysis of genetic studies from 10 countries finds infants born by C-section have more antibiotic resistance genes; antibiotic use and prematurity also fuel resistance.
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Vaccine candidate could fight antibiotic resistance
Scientists have announced several discoveries that will help the development of a carbohydrate-based vaccine for infections caused by Staphylococcus aureus and its “superbug” relative methicillin-resistant Staphylococcus aureus, or MRSA.
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Salmonella rates more prevalent in commercial poultry farm samples vs backyard farms
In a comparison of differently sized poultry farms, researchers at North Carolina State University found that rates of Salmonella in fecal and environmental samples were more prevalent on larger commercial farms than on smaller backyard farms.
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Optimal timing maximises Paxlovid benefits for treating COVID-19
Study suggests using the anti-COVID-19 treatment Paxlovid three to five days after symptoms emerge in patients and expanding global access to the drug may help reduce the severity and transmission of the SARS-CoV-2 virus.
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Rise seen in use of antibiotics for conditions they can’t treat – including COVID-19
A five-year trend study shows a rebound in inappropriate use after an early-pandemic dip, and a need to tackle overuse in all patients during viral illness outbreaks.
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Black women hospitalised in USA with blood infection resistant to last-resort antibiotic at increased risk of death
New research finds that the odds of death in black women with a bloodstream infection (BSI) caused by carbapenem-resistant enterobacterales (CRE) was twice that of black men or white women.
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Longest known SARS-CoV-2 infection of 613 days led to unique highly mutated variant
New research to be presented at next week’s ESCMID Global Congress highlights the risk of new immune-evasive SARS-CoV-2 variants emerging in immunocompromised patients.
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New class of antimicrobials discovered in soil bacteria
Scientists have mined Streptomyces for antibiotics for nearly a century, but the newly identified umbrella toxin escaped notice.
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Probiotic feed additive boosts growth and health in poultry in place of antibiotics
Researchers found that supplementing the diet of young chicks with a probiotic over 21 days significantly boosted the abundance of beneficial intestinal microorganisms.
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Antibiotics aren’t effective for most lower tract respiratory infections
Use of antibiotics provided no measurable impact on the severity or duration of coughs even if a bacterial infection was present, finds a large, prospective study of people who sought treatment for lower-respiratory tract infections.
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Biofilms play key role in reducing sensitivity to ionic silver in wound pathogens.
Bacterial pathogens in wounds that have been treated with ionic silver can adapt and become less sensitive - thanks to biofilm formation.
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Study suggests antibiotic-resistant ‘superbugs’ are being passed from cats and dogs to their owners
Pet dogs and cats in Portugal and the UK were carrying the same antibiotic-resistant bacteria as their owners, highlighting the importance of including pet-owning households in surveillance programmes for antibiotic resistance.
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Transmission risk of multidrug-resistant bacteria appears highest in hospital sinks
An outbreak in a pediatric hospital ward in Tokyo underscores the challenge of eliminating these bacteria from a healthcare facility.
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Membrane-piercing drugs bring multidrug-resistant pathogens to their knees
A research team has introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.