All Antimicrobial Resistance articles – Page 6
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NewsSingle-dose malaria treatment combining four existing drugs as effective as more onerous multi-day, multi-dose regimen
Hundreds of malaria patients participating in a clinical trial in Gabon in West Africa were cured via a single dose of a treatment that utilizes four widely available malaria drugs, according to a new study.
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NewsEvolving antibiotic resistance under pressure may lead to personalized treatment
A new study demonstrates the use of an experimental evolution approach to map genetic mutations in Acinetobacter baumannii treated with one of two uncommon antibiotics.
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NewsBiochemists search for cellular vulnerabilities in killer ‘superbugs’
Helen Zgurskaya and Valentin Rybenkov are leading a five-year, $5.3 million project funded by the National Institute of Allergy and Infectious Diseases to find new ways to deliver lifesaving drugs directly into resistant pathogens.
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NewsResearchers discover novel phage DNA modifications that offer new hope against antibiotic-resistant superbugs
A groundbreaking discovery reveals a unique way phages modify their DNA with arabinose sugars to protect themselves from bacterial defence systems. Natural DNA phage modifications occur at a higher rate than previously predicted, the study revealed.
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NewsDemographic shifts could boost drug-resistant infections across Europe
The rates of bloodstream infections caused by drug-resistant bacteria will increase substantially across Europe in the next five years, driven largely by aging populations, according to a new paper.
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NewsApproach to combat antibiotic resistance turns bacterium’s genes against it
Scientists have found that a structurally modified version of the drug florfenicol exploits drug resistance mechanisms in Mycobacterium abscessus to amplify the effect of the antibiotic perpetually.
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NewsNew antibiotic for drug-resistant bacteria found hiding in plain sight
Chemists have discovered a promising new antibiotic that shows activity against drug-resistant bacterial pathogens, including MRSA and VRE. Pre-methylenomycin C lactone was ‘hiding in plain sight’ — as an intermediate chemical in the natural process that produces the well-known antibiotic methylenomycin A.
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NewsRhizosphere metabolites influence the spread of antibiotic resistance genes in soil-plant systems
A study sheds new light on the complex mechanisms by which plants and their associated microorganisms contribute to the migration of ARGs through the environment, offering important implications for food safety and public health.
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NewsResearch alert: Bacterial chatter slows wound healing
Researchers have discovered a previously unrecognized mechanism by which Staphylococcus aureus delays wound healing. The study finds that quorum sensing is a key driver of delayed healing in wounds infected by S. aureus.
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OpinionCould livestock-originated probiotics replace synthetic antibiotics for livestock?
In many developing countries, the use of antibiotics in both humans and animals is often indiscriminate and poorly regulated. Could livestock-originated probiotics be a suitable replacement?
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NewsResearchers discover method to combat antibiotic treatment failure
Researchers explored ways to alter our own immune cells to help antibiotics work more effectively. They identified a small molecule that alters the body’s immune cells, forcing them to ’wake up’ dormant bacteria and make them more vulnerable to antibiotic treatment.
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News‘Cocktails’ of common pharmaceuticals in our waterways may promote antibiotic resistance
New research has shown, for the first time, how mixtures of commonly used medications which end up in our waterways and natural environments might increase the development of antibiotic resistant bacteria.
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NewsRoot chemistry determines how antibiotic resistance spreads from manure to crops
Researchers found that the rhizosphere, the narrow soil zone surrounding plant roots, is a major hotspot for the accumulation of manure-derived ARGs. Across eight common crops, ARG abundance in rhizosphere soil was on average 1.24 times higher than in bulk soil.
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NewsFreshwater snails are an overlooked reservoir of AMR, study reveals
Freshwater snails across Africa and the UK carry bacteria containing a wide range of antimicrobial resistance (AMR) genes, including those predicted to confer resistance against last-resort antibiotics, according to a new study led by AMI members.
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NewsWHO warns of widespread resistance to common antibiotics worldwide
One in six laboratory-confirmed bacterial infections causing common infections in people worldwide in 2023 were resistant to antibiotic treatments, according to a new World Health Organization (WHO) report.
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NewsScientists develop safer and more sustainable antimicrobials to prevent infection of cow udders
A new study has unveiled an alternative class of potent antimicrobial compounds that could be used in the agriculture industry to combat multi-drug-resistant bacteria that cause bovine mastitis.
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NewsSummer studentship: Shen explores how a novel peptide can destabilise the outer membrane of E. coli
Li Shen reports back on his AMI-sponsored summer studentship which investigated a novel antibiotic adjuvant at the Centre for Bacterial Resistance Biology, Imperial College London.
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NewsScientists uncover molecular mechanisms for bacterial lipid transport
Researchers have successfully applied cryo-electron microscopy (cryo-EM) to unveil the molecular structures of critical protein machines that transport lipids and maintain the outer membrane (OM) barrier of Gram-negative bacteria.
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NewsPeptide study paves path toward new weapon against antibiotic-resistant bacteria
New research into antimicrobial peptides, small chains of amino acids able to damage bacterial cells, shows why some peptides are more effective at doing that and also why some cells are more vulnerable.
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