All Antimicrobial Resistance articles – Page 6
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NewsUsing bacteria to improve microbiota resistance to pathogens
A new study aimed to identify the bacteria involved in the barrier effect shown by microbiota and prove their effectiveness in preventing the proliferation of pathogenic bacteria, with a view to developing a therapeutic strategy.
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NewsMirror molecules deliver a one-two punch to superbugs to fight infections
Researchers have created mirror-image molecules that both kill pathogens outright and rally the immune system—an advance aimed at the growing crisis of antimicrobial resistance.
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NewsUncovering the shield: gene duplication behind antifungal resistance in Madurella fahalii
Researchers used advanced genetic and biomolecular chemistry tools to uncover why itraconazole treatment fails against Madurella fahalii but not other Madurella species.
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NewsNew malaria control strategy efficiently kills parasites in the mosquito
A potent combination of antimalarial compounds added to bed nets blocked parasite transmission in mosquitoes while circumventing insecticide resistance, according to a new study.
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NewsMicroalgae remove antibiotic residues from wastewater, reducing environmental contamination
In the laboratory, the species Monoraphidium contortum removed some of the drugs added to the liquid and produced biomass with potential commercial value.
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NewsNew molecular movie reveals how antibiotic resistance to fusidic acid works
Researchers revealed how FusB, a resistance protein found in clinically resistant strains of the bacterium Staphylococcus aureus, can rescue ribosomes from the antibiotic fusidic acid. FusB works like a molecular crowbar to free the blocked ribosome.
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NewsWastewater treatment to fight the spread of antibiotic resistance
A metagenomics study has demonstrated that one type of bioreactor used in some wastewater plants – anaerobic membrane bioreactors – may be better at reducing the amount of ARGs released into the environment.
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NewsNew hope against superbugs: Promising antibiotic candidate discovered
An international team of researchers has discovered saarvienin A, a new type of glycopeptide antibiotic. Their findings introduce a compound with strong activity against highly resistant bacterial strains.
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NewsScientists evaluate in-vitro activity of ceftazidime-avibactam against carbapenem-resistant gram-negative bacteria
Scientists explored the in-vitro activity of ceftazidime-avibactam (CAZ-AVI) in clinical isolates of carbapenem-resistant gram-negative bacteria collected at the outpatient, emergency, and inpatient departments of the Indus Hospital, Karachi.
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FeaturesParasitic worms: an unexplored source of novel antimicrobials?
Novel antimicrobials are desperately needed to combat the AMR crisis, however, the clinical and preclinical pipeline for novel antimicrobials is virtually stagnant. This article will shed light on parasitic worms as an unexplored and underappreciated source of antimicrobial peptides.
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NewsTissue geometry drives bacterial infection: new mechanism uncovered
Researrchers have uncovered a novel mechanism by which tissue geometry regulates bacterial infection dynamics. The study employs a multidisciplinary approach to reveal how host tissue structure, mechanical forces, and cellular signaling shape infection patterns.
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NewsAntibiotics from human use are contaminating rivers worldwide, study shows
Millions of kilometres of rivers around the world are carrying antibiotic pollution at levels high enough to promote drug resistance and harm aquatic life, a new study warns.
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NewsScientists discover antibiotic resistance in newly identified bacterium
Staphylococcus borealis has been found to be resistant to several different types of antibiotics, posing a potentially significant problem for the elderly.
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NewsSpiritual healing sites could be linked to antibiotic-producing microorganisms
A study by AMI member Dr Gerry Quinn highlights the potential of spiritual healing sites as fertile ground for novel antibiotics, particularly from Streptomyces bacteria, known for producing the majority of current antibiotics.
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NewsShaken and stirred: why Klebsiella pneumoniae strain 007 poses a deadly threat
A new study has uncovered the secrets of a particular strain of the bacterium Klebsiella pneumoniae, revealing a potentially deadly genetic capacity for both antimicrobial resistance and virulence.
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NewsScientists introduce new engineered drug candidate for Mycobacterium abscessus to save lives
Scientists have introduced a promising drug candidate engineered to target a deadly and emerging infection. They took a hyper-detailed look into the problem of Mycobacterium abscessus, and chemically re-engineered a widely-used rifamycin antibiotic.
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NewsResearch advances on ‘displacing’ antibiotic resistance gene from bacteria
Scientists have identified essential genetic code for a method called plasmid curing, which aims to ‘displace’ antibiotic resistance genes from bacteria.
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Long ReadsCould spiritual healing sites be fertile ground for new antibiotics?
Common motifs between Streptomyces and sites of spiritual healing may help with the discovery of new sites for bioprospecting. Although there may be a temptation to dismiss the spiritual nature of the healing sites, it is important that researchers begin to understand these in the appropriate cultural and spiritual context.
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NewsBarriers remain to peptide-based therapies - but there are answers, reveals study
Peptide-based therapies offer the potential to transform how we treat a range of conditions - but have yet to be adopted for widespread clinical use. A new review uncovers the barriers to adoption and identifies ways to overcome these limitations.
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NewsCutting off parasite’s energy supply could help fight malaria
Once inside the body of an infected person, the malaria parasite relies on a process called glycolysis to produce energy and stay alive. Blocking the enzymes involved in this process could cut off the parasite’s primary energy source and kill it.