All Antimicrobial Resistance articles – Page 6
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NewsAgricultural azoles drive clinical azole resistance in Candida tropicalis via inducing aneuploidy
To define the causal role of agricultural azole fungicides in driving clinical azole resistance in the major human opportunistic fungal pathogen Candida tropicalis, researchers conducted a systematic study integrating experimental evolution, genomic characterization, and transcriptomic profiling.
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NewsTargeted therapeutics show promise in fighting off drug-resistant bacteria
A new study shows that when under attack, the body’s immune cells activate a cellular process called ‘mitochondrial fission’ to kill invading bacteria. Researchers found an experimental treatment called an HDAC6 inhibitor can re-activate the mitochondrial fission process in immune cells to fight invading bacteria.
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NewsWhy babies are dying and how we can stop it
A study has identified that the vast majority of neonatal deaths caused by infections in South Africa and other low-and-middle-income countries could be prevented through improved clinical care and targeted medical interventions.
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NewsWine’s leftovers could help wean chicken farms off antibiotics
Every year, millions of gallons of wine are pressed, leaving behind a mountain of pulpy residue that wineries struggle to dispose of. Now, researchers say this overlooked byproduct could serve as a replacement for the antibiotics routinely added to chicken feed.
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NewsSunlight and PVC pipes create a hidden driver of antibiotic resistance
New research shows that chemicals leaching from everyday PVC—especially after exposure to sunlight—can dramatically speed up the spread of resistance genes between bacteria. The effect was strongest at low to moderate concentrations, where the leachate triggered bacterial stress responses without killing the microbes.
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NewsEurope advances genomic surveillance of CCRE with landmark multi-country study
New survey results provide the most comprehensive genomic picture to date of carbapenem- and/or colistin-resistant Enterobacterales (CCRE) across hospitals in Europe.
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NewsFrom Helicobacter pylori to the AMR crisis: our interview with JAM Microbiology in Health and Disease Lead Editor Liang Wang
We get to know Professor Liang Wang, who has just been appointed as new Lead Editor in Microbiology in Health and Disease at the Journal of Applied Microbiology.
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NewsResearchers track the mutations that allow HIV-1 to escape broadly neutralizing antibodies
Scientists have established the most comprehensive view to date of how HIV-1 can escape broadly neutralizing antibodies. They have discovered viral mutations that make HIV-1 strains resistant to two bNAbs, 3BNC117 and 10-1074.
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NewsNew study shows cranberry juice may boost UTI antibiotics
Researchers recently exposed lab-grown strains of pathogenic Escherichia coli to cranberry juice. Preliminary findings suggest that compounds in the juice re-sensitize resistant strains to antibiotic treatment.
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NewsResearchers advance phage therapy in fight against antimicrobial resistance
Scientists have uncovered how Mycobacterium abscessus can evade bacteriophage therapy, and demonstrated a combination strategy to overcome this resistance, offering a pathway towards more effective and durable treatments.
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NewsAI speeds chemists’ search for better disinfectants
Scientists published their computational-experimental framework for developing quaternary ammonium compounds, or QACs, to kill bacteria. The method yielded 11 new QACs that show activity against antimicrobial-resistant bacteria.
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NewsResearchers identify natural compound that disarms drug-resistant bacteria
Scientists studying MRSA discovered that geranylgeranoic acid (GGA) – a naturally occurring fatty acid found in plants like ginger and turmeric – interferes with the bacteria’s virulence, its ability to infect, spread, defend itself, and cause disease.
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NewsWhy antibiotics may soon fail to curb the plague bacterium - and where we can find new strategies
A new review shows that while most infections caused by the Yersinia plague bacterium can currently be treated with antibiotics, concerns about rising antimicrobial resistance mean that we need to come up with new ways to disarm the bacteria instead of killing them.
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NewsComparing veterinary antimicrobial stewardship: Why Brazil needs stronger monitoring systems
A new comparative analysis reveals critical gaps in antimicrobial monitoring frameworks across three major economies, with significant implications for global public health and food security.
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NewsA universal toolkit for editing bacterial DNA
A major collaboration involving nine labs has transferred a particularly useful DNA editing system from E. coli into 14 new species of bacteria, spanning three major branches of the bacterial family tree.
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NewsGene-sharing myth challenged as bacteria shown to police DNA exchange
A new study reveals that bacteria can actively limit the spread of antibiotic resistance genes, using a newly characterized mechanism that blocks DNA transfer between cells. It focuses on how bacteria exchange genetic material through tiny intercellular bridges known as nanotubes.
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NewsCinnamic acid blocks plasmid conjugation to slow antibiotic resistance spread
A new study reveals that cinnamic acid, a widely used food additive found in cinnamon, can effectively inhibit plasmid‑mediated conjugation, a major route for the global spread of antibiotic resistance genes (ARGs).
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NewsResearchers disable antimicrobial resistance in cystic fibrosis-associated bacteria
A newly discovered mechanism renders antibiotic-resistant bacteria vulnerable by disabling both their individual resistance and a process known as cross-protection, the ability of resistant bacteria to shield nearby, otherwise sensitive strains.
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CareersQ&A: Meet Letters in Applied Microbiology Junior Editor Daniel Jesuwenu Ajose
We caught up with Daniel Jesuwenu Ajose, a Postdoctoral Research Fellow at the School of Biology and Environmental Sciences, University of Mpumalanga in South Africa, who is one of the newest Junior Editors with Letters in Applied Microbiology.