All Antimicrobial Resistance articles – Page 4
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Human clinical study launched using phage lysin to eliminate staph in the nasal microbiome
A “first-in-human” study with the novel drug candidate HY-133 began on 10 July with the recruitment of clinically healthy volunteers who tested positive for Staphylococcus aureus colonisation of the nose.
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AI opens door to safe, effective new antibiotics to combat resistant bacteria
A large language model—an AI tool like the one that powers ChatGPT—has been used to engineer a version of a bacteria-killing drug that was previously toxic in humans.
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Derivative of the long pepper battles bacterial biofilms
Scientists investigating the long pepper - known in traditional medicine for its treatment of a variety of illnesses - have created a derivative that disrupts bacterial chemical communication.
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Dual action antibiotic could make bacterial resistance nearly impossible
A new antibiotic that works by disrupting two different cellular targets would make it 100 million times more difficult for bacteria to evolve resistance, according to new research
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New agent effective against drug-resistant malaria parasites
Scientists have developed a promising new antimalarial agent, DIF-1(+3), which is a derivative of Dictyostelium differentiation-inducing factor-1 (DIF-1).
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New UK research networks will tackle antimicrobial resistance
Eight new UK networks, combining different research specialisms, will work together to tackle one of humanity’s biggest threats, antimicrobial resistance (AMR).
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AMAST Network launches to battle AMR in the agrifood system
AMAST – the AMR in Agrifood Systems Transdisciplinary Network, has been created to harness perspectives from across agrifood stakeholders and prepare new ways to tackle these challenges.
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Peptide cocktails could be key to fighting antibiotic resistance
A new study highlights the potential of random antimicrobial peptide mixtures to significantly reduce the risk of resistance evolution compared to single peptides, emphasizing the need for innovative solutions to outpace bacterial resistance and safeguard health.
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Scientists identify possible new transmission factor in hospital-acquired Klebsiella infections
The dangerous multidrug resistant (MDR) pathogen, Klebsiella, thrives under nutrient-deprived polymicrobial community conditions found in hospital environments, a new study reveals.
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Surgical Infection Society issues new guidelines on the management of intra-abdominal infection
The Surgical Infection Society (SIS) has presented new evidence-based guidelines for the management of intra-abdominal infection (IAI) in the peer-reviewed journal Surgical Infections. “These guidelines are critical in the ongoing work by the Surgical Infection Society to decrease the number of deaths from the most common ...
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Rising antimicrobial resistance in some Salmonella serovars isolated from retail chicken meat
Salmonella infections are a major public health issue in the United States, causing over 1.3 million illnesses annually. These infections are a leading cause of foodborne illness, often traced back to raw or undercooked poultry meat and eggs. Source: National Institute of Allergy and Infectious Diseases Scanning electron ...
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New ECDC Director Pamela Rendi-Wagner emphasises importance of restoring public trust in science after pandemic
Incoming ECDC Director Dr Pamela Rendi Wagner has outlined her vision for the agency, highlighting the challenges to public health after the COVID-19 pandemic, including war in Europe, climate change, and increasing social inequalities.
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Urgent action needed to combat rising antimalarial resistance in Africa
Urgent action is needed to prevent a surge in malaria-related sickness and death in eastern Africa, scientists say.
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Harnessing big data helps scientists hone in on new antimicrobials
Scientists have detailed a new method of identifying antimicrobial enzymes from large datasets of bacterial proteins, which could provide a solution to antibiotic resistance.
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Scientists pioneer comprehensive derivative synthesis method for developing new antimicrobial drugs
A method to screen a wide variety of drug candidates without laborious purification steps could advance the fight against drug-resistant bacteria.
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E. coli variant may cause antimicrobial resistance in dogs and humans
Researchers studying antimicrobial-resistant E. coli – the leading cause of human death due to antimicrobial resistance worldwide – have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.
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Discharge of untreated hospital effluent is a key driver of multidrug resistance, study finds
A new study has highlighted the discharge of untreated hospital effluent to the environment as a major driver of multidrug resistance among the microbial community.
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AI able to identify drug-resistant typhoid-like infection from microscopy images in matter of hours
Artificial intelligence (AI) could be used to identify drug resistant infections, significantly reducing the time taken for a correct diagnosis, researchers have shown. An algorithm can be trained to identify drug-resistant bacteria correctly from microscopy images alone.
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Scientists discover how to improve vaccine responses to potentially deadly bacterium
Researchers have shown in an animal model that targeting a key suppressive immune molecule (IL-10) during the delivery of a vaccine improves the ability of the vaccine to protect against infection.
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Western superbugs do not dominate in Pakistan, study reveals
Certain antibiotic-resistant strains of bacteria endemic to the UK, Norway and the USA have not taken hold in Pakistan despite the widespread use of antibiotics in this region.