All Antimicrobial Resistance articles – Page 2
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Model can calculate the often hidden costs of fungicide resistance
An international research team has developed a mathematical model that can be used to calculate the economic and often hidden costs of fungicide resistance. They used a model that can be used to calculate the spread of fungal diseases in several fields.
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In hard-to-treat form of tuberculosis, shorter, gentler therapy shows unequal benefit
A first-ever clinical trial exclusively conducted among people with a hard-to-treat form of tuberculosis known as pre-extensively drug-resistant TB shows many patients benefit from shorter, simpler regimens.
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Hidden bacterial redundancy could be antibiotic game-changer
Staphylococcus aureus possesses a surprising level of metabolic redundancy, allowing it to survive even when key enzymes are knocked out, a new study finds. However, when two specific enzymes are removed, staph doesn’t infect its host as readily.
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Penicillin allergy testing needed to fight antibiotic resistance
Removing incorrect penicillin allergy labels on GP records could combat antibiotic resistance and save lives, an NIHR-funded clinical trial has found.
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How superfungus Candida auris rebuilds its cell walls to withstand antifungal treatment
A groundbreaking study has revealed how the multidrug-resistant superfungus Candida auris uniquely reconstructs its cell wall to survive antifungal treatments.
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Antibiotic resistance predicts higher mortality risk in 17-year follow-up
A population-based study finds that in addition to antibiotic use, diet, sex, living environment, income level and certain gut bacteria are associated with a higher burden of resistance.
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Scientists uncover quality and antibiotic resistance risks in livestock probiotics in China
Researchers analyzed 95 non-duplicate commercial probiotic products for livestock from across China, revealing significant issues in labeling accuracy, strain composition, and the presence of antibiotic resistance genes (ARGs).
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Clove oil offers promise as antimicrobial alternative that could target healthcare-associated infections in low-income countries
A research study presented at MLS Future Forum 2025 has revealed that clove essential oil could offer potential as a sustainable alternative to conventional antimicrobials. While clove oil showed antibacterial and antifungal effects, turpentine oil had little antimicrobial activity.
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Researchers develop mRNA-based vaccine against a deadly plague-causing bacterium
Researchers have used the platform developed for COVID-19 vaccines to create the world’s first mRNA-based vaccine against the deadly, antibiotic-resistant bacterium behind pneumonic plague.
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Substances isolated from marine sponges show potential for treating malária
In pre-clinical tests, compounds called batzelladins were found to be effective even against strains of Plasmodium that are resistant to conventional antimalarial drugs.
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Chameleon plant polysccharide targets acute pneumonia with H1N1 and MRSA coinfection
A new study discusses how an anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut–lung axis and NLRP3 inflammasome activation.
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Thirty years of research shows increased resistance in fungi
Fungi are increasingly resistant to antifungals, and the variation in resistance has significantly increased, reveals an analysis of more than 12,000 lung samples collected over thirty years in Dutch hospitals.
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New breakthrough uncovers how to kill ‘zombie’ TB cells resistant to antibiotics
Researchers exposed a library of over 500,000 genetically modified tuberculosis bacteria to two commonly used antibiotics. By analysing the survivors, they pinpointed genes whose disruption significantly reduced the number of surviving persisters.
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Multiresistant intestinal bacteria: Displacement through food competition
Researchers made use of food competition to figure out how potentially dangerous multi-resistant bacteria could be effectively removed from the gut before reaching the bloodstream and causing serious problems.
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Scientists target ‘molecular machine’ in the war against antimicrobial resistance
The ‘molecular machine’ flagellum is essential for bacteria to cause infection, allowing bacteria to ‘swim’ around the bloodstream until finding something to infect. But it could also be a target for antibiotics.
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Antibiotics are failing in many countries in Africa, new study reveals
The largest retrospective study on resistance to antibiotics in Africa highlights the need for major investments to enhance laboratory capabilities and healthcare access.
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Prescribing fewer antibiotics might not be enough to combat threat of superbugs, says new research
Antimicrobial resistance is still spreading in the environment despite a reduction in the amounts of antibiotic drugs prescribed, according to a new study. Multiple approaches will be required to tackle the increasing threat of antimicrobial resistance to public health.
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International comparison reveals gender differences in antimicrobial resistance
A recent study analysed the DNA map of more than 14,000 gut metagenomes in a global dataset and found differences in antibiotic resistance between genders. In high-income countries, women had more antibiotic resistance genes than men.
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Excessive use of disinfectants in intensive care patients may increase the risk of antibiotic-resistant infections
An international study has, for the first time, revealed a strong and direct link between the rise of antibiotic-resistant bacteria and universal disinfection procedures applied to patients in intensive care units.
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Evolutionary model for antibiotic resistance reveals dose timing critical to care
The study that uses a “fitness seascape” to incorporate a patient’s dosage schedule into models that predict whether an infection will develop antibiotic resistance has found that inconsistent timing and missing early doses can lead to treatment failure.