All Antimicrobial Resistance articles – Page 14
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NewsEfficacy of topical Nigella sativa L. with vinegar in the treatment of acne vulgaris
A team of researchers in India assessed the efficacy and safety of a topical formulation combining Kalonji and Sirka for the treatment of mild to moderate acne vulgaris. The formulation was compared with a 5% benzoyl peroxide.
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NewsDeadly bacteria developed the ability to produce antimicrobials and wiped-out competitors
A drug-resistant type of bacteria that has adapted to health care settings evolved in the past several years to weaponize an antimicrobial genetic tool, eliminating its cousins and replacing them as the dominant strain.
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NewsTeam finds regional, age-related trends in exposure to drug-resistant pathogen
A study from 10 US states found drug-resistant Campylobacter jejuni infections were highest in the 20-39 age group and that quinolone-resistant C. jejuni infections increased from 22.6% of those tested in 2013 to 33.54% in 2019. It identified regional differences in C. jejuni resistance to quinolones and six other classes of antibiotics.
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NewsFDA-approved dialysis drug may help fight against antimicrobial resistance
In account of the imminent threat of antimicrobial resistance (AMR), a study revealed that the FDA-approved sevelamer, which is used to treat chronic kidney disease undergoing dialysis, is successful in the removal of other off-target antibiotics (vancomycin and daptomycin) from the gut.
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NewsProfessor Sabiha Essack wins Christiana Figueres Policy to Practice Award
Professor Sabiha Essack, the South African Research Chair in Antibiotic Resistance and One Health, Professor in Pharmaceutical Sciences at the University of KwaZulu-Natal, has been awarded the Christiana Figueres Policy to Practice Award.
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NewsScientists discover protein key to bacteria’s survival in extreme environments
A new discovery sheds light on how certain bacteria – including strains that cause food poisoning and anthrax – form spores for survival.
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NewsRice research team creates universal RNA barcoding system for tracking gene transfer in bacteria
An interdisciplinary group of researchers at Rice University has developed an innovative RNA “barcoding” method to track gene transfer in microbial communities, providing new insights into how genes move across species.
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NewsResearch uncovers new strategy to reduce tissue damage from flesh-eating bacteria
A new study reveals a novel approach to mitigating tissue damage caused by Streptococcus pyogenes, the flesh-eating bacterium responsible for severe infections such as necrotizing fasciitis.
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NewsAdd some spice: Curcumin helps treat Mycobacterium abscessus
Researchers have found that adding curcumin boosts the efficacy of bedaquiline, an antimycobacterial used to treat tuberculosis, in combating M. abscessus infections. Curcumin is the compound that gives turmeric its characteristic bright orange color.
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NewsHelicobacter pylori treatment practices in the Asia-Pacific region
Researchers conducted an online survey of clinicians in the Asia-Pacific region to investigate treatment policies for H. pylori and confirmed that there is a growing consensus of the importance of primary and secondary prevention against H. pylori.
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NewsGenetic resistance factors and antimicrobial resistance phenotypes in methicillin-resistant Staphylococcus aureus isolates of animals and humans
A new study identified three functional protein families in MRSA, through sequencing, that confer extensive antibiotic resistance independent of the known antibiotic resistance determinants, mecA and mecC.
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NewsPromising new research shows potential to cure recurrent urinary tract infectionsed
Researchers examine the effectiveness of nanogel as a drug delivery system to direct antibiotics into targeted infected cells to improve UTI treatment.
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NewsPurified immunoglobulin F(ab′) 2 prevents lethal staphylococcal enterotoxin B intoxication in mice and rhesus monkeys
Purified F(ab′)2 fragments are an effective antidote to lethal SEB doses in mice and rhesus monkeys, and therefore might be a favorable candidate for treating patients with severe SEB intoxication, a new study suggests.
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NewsAntimicrobial resistance in soil bacteria without the use of antibiotics
Overuse of antibiotics is currently the primary reason for the rise of antimicrobial resistance (AMR), but researchers have shown that AMR can be found in soil bacterial communities due to microbial interactions too, driven by a species of predatory bacteria.
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NewssiRNA-AGO2 complex inhibits bacterial gene translation: a novel therapeutic strategy for superbug infection
Scientists have demonstrated that exosomes can serve as delivery vehicles to introduce AGO2-loaded siRNA into the cytoplasm of bacteria, and in turn down-regulated gene expression of the mRNA that shares sequence complementarity to the siRNA.
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NewsNovel insights into Candida glabrata in pregnant women’s reproductive tracts in Hainan
A study of Candida glabrata in pregnant women with vaginal discomfort at Haikou Maternal and Child Health Hospital found that 64.5% of the 594 yeast isolates (383 isolates) showed resistance (R) or intermediate (I) phenotypes to at least one of four commonly used antifungals.
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NewsBacterial ‘jumping genes’ can target and control chromosome ends
Researchers have discovered a new mechanism that transposons, or “jumping genes” use to survive and propagate in bacteria with linear DNA, with applications in biotechnology and drug development.
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NewsA 'Trojan Horse' approach to develop new antimalarial drugs
Researchers have discovered a key process whereby malarial parasites take up a human blood cell enzyme, which could provide a new approach for antimalarial treatment.
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NewsCentauri Therapeutics selects first clinical candidate for immunotherapeutic treatment of Gram-negative bacterial infections
Centauri Therapeutics Limited has announced the selection of its first clinical candidate in the ABX-01 programme. The compound is designed to target serious Gram-negative bacterial infections in the lung.
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NewsStudy uncovers the core principles of low-resistance antibiotics
Researchers have demonstrated that a dual-target approach, combining membrane disruption with an additional critical cellular pathway, significantly prevents the development of resistance in bacteria.