All Disease Treatment & Prevention articles – Page 3
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Scientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
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Researchers unlock new potential porcine virus treatment
Researchers have identified a novel small molecule for the development of preventative treatment for porcine reproductive and respiratory syndrome virus (PRRSV).
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Mpox: a better understanding of tecovirimat resistance
Through biochemical and structural studies, researchers managed to find out how the mutation of an enzyme could affect the interactions between it and the antiviral drug against mpox virus, tecovirimat, hence leading to a better understanding in developing new therapeutic approach against all mpox strains.
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Microbiome as a potential key to better treatment: Clinical study on new therapy for Crohn’s disease
A joint research project has found that a combination of dietary therapy and fecal microbiome transfer (FMT) greatly alleviate intestinal inflammation in mice. A clinical trial on this new therapeutic approach is under way to potentially treat Crohn’s disease.
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A realistic ‘micro-gut’ model reflects the relationship between gut microbes and human diseases
An innovative and more physiologically relevant 3D micro-gut model, known as Gut-Microbiome on a chip (GMoC), provides an in-depth understanding of the complex interactions between the microbial community within the gut microbiome and their impacts on human gut health.
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Why some kids get sicker: The hidden power of nose bacteria
A scoping review unravels how bacterial colonization in the respiratory tract impacts both the severity of respiratory syncytial virus (RSV) infections and long-term respiratory health in children.
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AI accelerates the search for new tuberculosis drug targets
A novel biotechnology was developed to utilize artificial intelligence (AI) as a high-throughput way to identify more effective antimicrobial candidates to treat the multi-drug resistant Mycobacterium tuberculosis and understand their underlying modes of action.
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First success in overcoming gene therapy challenges deploys nanomachines loaded with wine ingredients
Scientists have demonstrated the ability to overcome significant challenges in gene therapy using adeno-associated virus vectors (AAV) by employing a novel smart nanomachine equipped with AAV.
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New phage platform pinpoints viruses that can deliver a knockout blow for killer bacteria
An international group of microbial experts has launched a powerful and flexible free online genomic toolkit for more rapid development of phage therapy. They say it is capable of assessing if a phage is suitable for a targeted therapy in under 10 minutes.
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NIH-funded clinical trial will evaluate new dengue therapeutic
A clinical trial is testing an experimental treatment designed to help people suffering the effects of dengue. An investigational therapeutic will be administered to adult volunteers who have been exposed to a weakened strain that causes a mild form of the disease.
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Antibody treatment prevents severe bird flu in monkeys
A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, a new study reports.
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Study finds three new safe, effective ways to treat drug-resistant tuberculosis
An international clinical trial has found three new safe and effective drug regimens for tuberculosis that is resistant to rifampin, the most effective of the first-line antibiotics used to treat TB.
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Could faecal microbiota transplantation help patients heal after stem cell transplantation?
A study, from a part of an ongoing clinical trial, has reported the safety of oral faecal microbiota transplantation (FMT) to help patients recover from the loss of gut microbiome after allogeneic stem cell transplantation for blood cancers.
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New study highlights role of lean red meat in gut and heart health as part of a balanced healthy diet
A research has suggested that a balanced and healthy dietary pattern that includes lean red meat has a beneficial role in gut microbiota changes and cardiovascular health.
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Structural insights reveal potential drug target in trypanosome parasites
A research group has recently characterised the structural differences between human and trypanosomal nuclear cap-binding complex, a key player in cellular RNA metabolism, for future drug development of trypanosomal diseases.
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Shorter, smarter, safer: Short-course antibiotics can revolutionize healthcare
Researchers suggest that short-course antibiotic treatment could be the next game-changing strategy to treat ventilator-associated pneumonia (VAP) in various economic settings. It provides a cost-effective and practical approach that benefits both patients and the healthcare systems.
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New paper creates roadmap for the next generation of bioelectronic medicine
A new paper offers a roadmap to the future of bioelectronic medicine — which makes use of electrical signals instead of drugs to diagnose and treat disease.
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Dihydroartemisinin inhibits T cell activation in people living with HIV with incomplete immune reconstitution in vitro
A new study provides insights into the biological mechanisms underlying incomplete immune reconstitution in people with HIV and supports dihydroartemisinin’s potential as a therapeutic agent.
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Scientists uncover structure of critical component in deadly Nipah virus
Through the structural and functional study of the deadly Nipah virus, a research team has identified a crucial viral component, viral polymerase complex, within its multiplication machinery, with which a part of the enzyme could potentially serve as a therapeutic target.
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Research using non-toxic bacteria to fight high-mortality cancers prepares for clinical trials
A promising research study in treating high mortality late-stage cancers with a non-toxic bacterial therapy - BacID - has proven to be safe and more targeted. The newly developed treatment would undergo clinical trials with cancer patients in 2027.