All Disease Treatment & Prevention articles – Page 2
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Clinical trial finds safe, effective treatment for children with severe post-Covid syndrome
Researchers have discovered that a drug designed to treat Celiac disease supported a more rapid return to normal activities for patients following COVID. A small, randomized clinical trialfound the oral drug larazotide was both safe and effective in treating children with MIS-C.
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‘One and done’: A single shot at birth may shield children from HIV for years, study finds
A new study shows that delivering a single injection of gene therapy at birth may offer years-long protection against HIV, tapping into a critical window in early life that could reshape the fight against pediatric infections in high-risk regions.
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New AI tool accelerates mRNA-based treatments for viruses, cancers, genetic disorders
A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various cell types.
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Can a compound produced by deep-sea bacteria treat cancer?
Investigators purified a long-chain sugar molecule, or exopolysaccharide, from deep-sea bacteria and demonstrated that it triggers pyroptosis—an inflammatory form of programmed cell death—to inhibit tumor growth.
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Study identifies world-first treatments to prevent a life-threatening virus infection
A study found two HIV antivirals already on the market can suppress transmission of HTLV-1 in humanised mice and prevent disease. When used in combination with a compound that induces cell death, infected cells were killed – flagging a potential future curative strategy.
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Study reveals engineered bacterial vesicles to combat antimicrobial resistance
Researchers studying extracellular vesicles (EVs)-membrane-bound nanoparticles released by cells that transport biologically active molecules like proteins or nucleic acids have engineered EVs derived from lactic acid bacteria to carry pathogen-specific endolysins on their surface.
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The gut’s secret weapon: viruses that heal
A comprehensive new review reveals how gut viruses interact with gut bacteria and host immunity, highlighting their roles in conditions like inflammatory bowel disease, colorectal cancer, and C. difficile infection. The findings offer a compelling case for harnessing the virome in novel therapies to reshape gut ecology and restore health.
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When bacteria get hungry, they kill – and eat – their neighbors
Scientists have discovered a gruesome microbial survival strategy: when food is scarce, some bacteria kill and consume their neighbors. The researchers show that under nutrient-limited conditions, bacteria use a specialized weapon — the Type VI Secretion System (T6SS) — to attack, kill, and slowly absorb nutrients from other bacterial cells.
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People with COVID-like symptoms took up to nine months post-infection to regain mental well-being
New research finds that people with COVID-like symptoms returned to optimal physical well-being an average of three months after infection, but took up to nine months to return to top mental well-being.
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Twin study detects gut bacteria that play a role in development of multiple sclerosis
Researchers examined stool samples from 81 pairs of twins, and compared their composition between siblings. They identified 51 taxa—groups of microorganisms—that differed in abundance between twins with and without MS symptoms.
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New source of natural antibiotics hidden within our own proteins identified
A team of scientists has identified a new type of antimicrobial peptides (AMPs) found in human proteins that are capable of selectively eliminating multidrug-resistant bacteria, particularly of the gram-negative type, responsible for serious hospital acquired infections.
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Heatwaves greatly influence parasite burden; likely spread of disease
New research implies that heatwaves have a major influence on the spread of many diseases – and that many existing predictive models have overlooked this complexity. Differences in heatwaves can increase disease burden by up to 13 times in an animal model.
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Researchers engineer a herpes virus to turn on T cells for immunotherapy
Researchers have identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival - a promising tool in the fight against cancer.
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Gut fungi breakthrough: Novel fungus offers hope for metabolic diseases
Scientists have unveiled a gut fungus that could transform treatment for metabolic dysfunction-associated steatohepatitis (MASH). The fungus produces a compound that blocks CerS6, an enzyme responsible for producing ceramides, fat molecules linked to metabolic disorders.
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First all-oral treatment for a rare but deadly strain of sleeping sickness now available
A handful of patients in Ethiopia, Malawi, Tanzania, Zambia, and Zimbabwe, as well as foreign travellers, have now been treated with a medicine that is revolutionizing care for patients with rhodesiense sleeping sickness.
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Targeted nanoparticles show promise for more effective antifungal treatments
Researchers have developed a new nanotechnology-based approach that could improve treatment of fungal infections, particularly those caused by the increasingly drug-resistant Candida species.
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COVID-19 caused by the Omicron variant in lung transplant recipients: a single center case series
A new study investigates the risk factors for developing severe disease in lung transplant patients as a result of the Omicron variant of Covid-19.
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Probiotic supplementation may help reduce chemotherapy side effects in breast cancer
A new study shows that probiotics with seven strains have a potential effect in patients with breast cancer, especially in the improvement of common chemotherapy-related side effects such as fatigue and nausea.
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Researchers reveal how fungi ‘manipulate’ the course of tumors
In pancreatic ductal adenocarcinoma (PDA), the abnormal colonization of fungal communities has become a research hotspot. New research indicates that Malassezia is not only a ’marker’ in the tumor microenvironment but also a potential driver of cancer development.
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Novel point of attack to combat dangerous tropical diseases
Researchers have compiled a high-precision inventory of the membrane proteins of cell organelles of the African sleeping sickness pathogen, offering hope for new treatment approaches for dangerous tropical diseases.