All Disease Treatment & Prevention articles – Page 2
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NewsStudy writes the catalog of plasma membrane repair proteins
A new study identifies 80 proteins involved in plasma membrane repair in budding yeast, laying the foundation for membrane repair studies and future therapeutic applications.
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NewsResearchers make probiotic safer for immunocompromised patients
Researchers have modified a probiotic yeast to make it safer for use by immunocompromised people, older adults and infants. Testing in an animal model found the modified yeast is less likely to cause infection than unmodified strains of the same organism.
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NewsGut microbes rewrite the rules of cancer immunotherapy
A review synthesizes growing evidence showing that commensal microbes enhance anti-tumor immunity by producing immune-active metabolites, remodeling the tumor microenvironment, and activating key immune cells such as dendritic cells and cytotoxic T cells.
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News How viruses mess with our brains
What impact does a viral infection have on our memory, attention, and concentration? A new review has identified several biological markers associated with cognitive decline in the context of infection. It also provides a solid foundation for future research.
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NewsNew compound stops common complications after intestinal surgery
Researchers have synthesized and tested a new compound in mice that shows promise in protecting the liver from damage and improving nutrient absorption after small bowel resection. They also found that the drug works only on the gastrointestinal tract.
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NewsScientists engineer ‘living eye drop’ to support corneal healing
A proof-of-concept study demonstrates that the harmless eye-dwelling microbe Corynebacterium mastitidis can be genetically modified to secrete an anti-inflammatory therapeutic that promotes healing following corneal injury in a mouse model.
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NewsHow microbes protect the lungs against allergies
A study has revealed that microbes protect the lungs from subsequently developing allergies and asthma. This long-term protection is “memorized” not by immune system cells but by fibroblasts, structural cells in the lungs.
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NewsStudy reveals how gut bacteria and diet can reprogram fat to burn more energy
A new study shows that a low‑protein diet activates a precise set of gut microbes that send chemical signals throughout the body, prompting fat tissue to burn energy instead of storing it. The findings uncover a previously unknown biological pathway linking diet, the gut microbiome and metabolic health.
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NewsFrom gut to lung: A microbial signal that strengthens early immune defense
Researchers report that a gut microbiota–derived metabolite can directly shape immune responses in bacterial pneumonia. Using a Klebsiella pneumoniae infection model, the team demonstrated that butyric acid restores the function of CX3CR1-positive natural killer cells.
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NewsHow periodontitis-linked bacteria accelerate osteoporosis-like bone loss through the gut
Researchers reveal that salivary bacteria from gum disease alter gut metabolism, driving osteoclast activity and systemic bone loss. They analyzed salivary microbiota from individuals with advanced periodontitis and compared them with samples from periodontally healthy donors.
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NewsGut microbiome connected with heart disease precursor
Before the onset of cardiovascular disease symptoms, people often develop dyslipidemia, or abnormal levels of lipids in the blood. Microbiologists have identified microbial taxa more likely to be found in people with dyslipidemia than in people with healthy levels of cholesterol and triglycerides.
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NewsTargeting the gut–lung microbiome to reduce infections in severe pancreatitis
Researchers report new clinical evidence that a fungal probiotic may reduce hospital-acquired infections in patients with severe acute pancreatitis. Patients receiving Saccharomyces boulardii alongside standard enteral nutrition experienced significantly fewer infections than those receiving nutrition alone.
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NewsBacteria found in mouth and gut may help protect against severe peanut allergic reactions
One of the big mysteries in food allergy is why two people with similar levels of peanut specific antibodies can react so differently. A new study shows for the first time how gut bacteria break down parts of an allergenic food and influence how a person reacts to peanuts.
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NewsChemically ‘stapled’ peptides used to target difficult-to-treat cancers
Researchers have developed a new technology that uses bacteria to build, chemically stabilise, and test millions of potential drug molecules inside living cells. The bacteria produce vast libraries of peptide molecules, and chemically stabilise them into defined shapes while they are being tested inside the cell.
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NewsFecal transplants from older mice significantly improve ovarian function and fertility in younger mice
A new study details how fecal transplants from older female mice significantly improve ovarian function and fertility in young mice. The surprising results reveal a direct link between the microbiome of the gut and ovarian health and function.
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NewsCell-free DNA offers early warning for bloodstream infections in kids with leukemia
Researchers show that microbial cell-free DNA sequencing can predict bloodstream infections in children with leukemia days before the symptoms appear. Plasma microbial cell-free DNA sequencing (mcfDNA-Seq) offer a potential approach to protecting vulnerable patients by allowing treatment to start before the patient gets sick.
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NewsNew study demonstrates universal newborn cCMV screening leads to earlier detection and increased identification of mild hearing loss
A new retrospective cohort study examining the impact of Minnesota’s first-in-the-nation mandated universal newborn screening for congenital cytomegalovirus (cCMV) shows that universal screening significantly decreased the age at first audiology visit and increased identification of mild hearing loss in infants.
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NewsAkkermansia muciniphila PROBIO therapy promotes arginine biosynthesis and reverses reproductive impairments in polycystic ovary syndrome rats
A research study investigated the therapeutic potential of Akkermansia muciniphila PROBIO (AP) in a dehydroepiandrosterone-induced PCOS rat model, revealing significant improvements in reproductive and metabolic parameters through modulation of gut microbiota and enhancement of arginine biosynthesis.
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NewsEnhanced inner ear tropism of Adeno-Associated Virus (AAV) vectors via peptide display on AAV1 capsid
Researchers improving efficiacy of AAV)-mediated gene therapy for the inner ear screened and inserted short peptide motifs onto the surface of the AAV1 capsid. These engineered vectors achieved markedly higher transduction rates in inner ear hair cells and supporting cells.
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NewsBiomarkers indicating higher liver cancer risk in chronic hepatitis B patients identified
Researchers have identified Hepatitis B RNA serum levels as a biomarker that more accurately stratifies risk of liver cancer in individuals who have been functionally cured of chronic hepatitis B.