All Disease Treatment & Prevention articles – Page 2
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Global study reveals stark differences between females and males in major causes of disease burden
Globally, there are substantial differences between females and males (aged 10 and older) when it comes to health, with limited progress in bridging these health gaps over the past 30 years, according to a new study.
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Phytopathology Research Forum highlights advances in plant pathology research in China
The event aims to facilitate discussions about cutting-edge developments in plant pathology research, phytopathology research innovations, and domestic and foreign academic exchanges.
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New study on immune cells interaction unlocks novel treatment targets for Chikungunya virus
Insights from this study open doors for the development of new drugs targeting immune cells to combat CHIKV and similar viruses.
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Experimental NIH malaria monoclonal antibody protective in Malian children
One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country’s six-month malaria season, according to the results of a mid-stage clinical trial.
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Study finds artificial intelligence can develop treatments to prevent superbugs
Researchers developed an AI model that can determine the best combination and timeline to use when prescribing drugs to treat a bacterial infection, based solely on how quickly the bacteria grow given certain perturbations.
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Engineers muffle invading pathogens with a ‘molecular mask’
Researchers are developing a hydrogel therapy that acts as a first line of defense against viruses and other biological threats. The peptides that make up this gel prevent viruses such as SARS-CoV-2 from attaching to and entering cells.
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Optimal timing maximises Paxlovid benefits for treating COVID-19
Study suggests using the anti-COVID-19 treatment Paxlovid three to five days after symptoms emerge in patients and expanding global access to the drug may help reduce the severity and transmission of the SARS-CoV-2 virus.
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Impact of COVID-19-related nonpharmaceutical interventions on diarrheal diseases and zoonotic salmonella
The results showed that while the detection rate of most foodborne pathogens declined in China during the pandemic there was an abnormal increase in the detection rate of non-typhoidal Salmonella.
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Antibiotics aren’t effective for most lower tract respiratory infections
Use of antibiotics provided no measurable impact on the severity or duration of coughs even if a bacterial infection was present, finds a large, prospective study of people who sought treatment for lower-respiratory tract infections.
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Biofilms play key role in reducing sensitivity to ionic silver in wound pathogens.
Bacterial pathogens in wounds that have been treated with ionic silver can adapt and become less sensitive - thanks to biofilm formation.
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Mechanism of action of the hepatitis B and D virus cell entry inhibitor bulevirtide deciphered
An international research team has succeeded in deciphering the molecular structure of bulevirtide in complex with the HBV/HDV receptor NTCP at the molecular level.
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Significant decline of neutralising antibodies to monkeypox virus during the first month after vaccination
New research shows that even in men who receive two doses of mpox vaccine intradermally, their level of antibodies to the virus falls to low or zero within the first few months if they have not received a previous smallpox vaccine.
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Scientists have a new tool in the race to improve the diagnosis and prognosis of sepsis
Scientists identify unique molecular signatures of sepsis and use AI to improve diagnosis and identify patients most likely to develop severe symptoms and suffer poor outcomes.
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A combination of approved drugs enhances the delivery of anti-bacterial medications to treat tuberculosis
Scientists repurposed approved drugs that they originally tested to normalize blood vessels surrounding tumors to improve drug delivery to cancer cells.
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Scientists develop an innovative compound effective against malaria and leishmaniasis
Initially designed for malaria, this drug shows high efficacy against leishmaniasis, representing a unique and promising breakthrough for the treatment of both infections.
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Implantable device delivers HIV antiviral with more potency than oral drugs
A study shows that a nanofluidic implant delivered an HIV drug that achieved more potency than other forms of drug administration (oral) and other HIV drugs.
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New understanding of the gut immune system may hold promise for Crohn’s disease patients
A team of scientists have uncovered an overlooked mechanism in the gut immune system of patients suffering from severe cases of Crohn’s disease. The discovery may help define how to treat patients with severe Crohn’s disease.
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Study reveas how virus hijacks insect sperm to control disease vectors and pests
A new study reveals how viral proteins from symbiotic bacteria cause sterility in insects.
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Nanoparticles containing lupeol treat visceral leishmaniasis with scant side effects
In animal tests conducted at São Paulo State University (UNESP), the strategy reduced spleen and liver parasite numbers by 99.9%.
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Scientists reveal what makes ‘bad’ bacteria life-threatening
Researchers have discovered that a mutation allows some E. coli bacteria to cause severe disease in people while other bacteria are harmless, a finding that could help to combat antibiotic resistance.