All Disease Treatment & Prevention articles
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When bacteria get hungry, they kill – and eat – their neighbors
Scientists have discovered a gruesome microbial survival strategy: when food is scarce, some bacteria kill and consume their neighbors. The researchers show that under nutrient-limited conditions, bacteria use a specialized weapon — the Type VI Secretion System (T6SS) — to attack, kill, and slowly absorb nutrients from other bacterial cells.
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People with COVID-like symptoms took up to nine months post-infection to regain mental well-being
New research finds that people with COVID-like symptoms returned to optimal physical well-being an average of three months after infection, but took up to nine months to return to top mental well-being.
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Twin study detects gut bacteria that play a role in development of multiple sclerosis
Researchers examined stool samples from 81 pairs of twins, and compared their composition between siblings. They identified 51 taxa—groups of microorganisms—that differed in abundance between twins with and without MS symptoms.
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New source of natural antibiotics hidden within our own proteins identified
A team of scientists has identified a new type of antimicrobial peptides (AMPs) found in human proteins that are capable of selectively eliminating multidrug-resistant bacteria, particularly of the gram-negative type, responsible for serious hospital acquired infections.
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Heatwaves greatly influence parasite burden; likely spread of disease
New research implies that heatwaves have a major influence on the spread of many diseases – and that many existing predictive models have overlooked this complexity. Differences in heatwaves can increase disease burden by up to 13 times in an animal model.
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Researchers engineer a herpes virus to turn on T cells for immunotherapy
Researchers have identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival - a promising tool in the fight against cancer.
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Gut fungi breakthrough: Novel fungus offers hope for metabolic diseases
Scientists have unveiled a gut fungus that could transform treatment for metabolic dysfunction-associated steatohepatitis (MASH). The fungus produces a compound that blocks CerS6, an enzyme responsible for producing ceramides, fat molecules linked to metabolic disorders.
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First all-oral treatment for a rare but deadly strain of sleeping sickness now available
A handful of patients in Ethiopia, Malawi, Tanzania, Zambia, and Zimbabwe, as well as foreign travellers, have now been treated with a medicine that is revolutionizing care for patients with rhodesiense sleeping sickness.
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Targeted nanoparticles show promise for more effective antifungal treatments
Researchers have developed a new nanotechnology-based approach that could improve treatment of fungal infections, particularly those caused by the increasingly drug-resistant Candida species.
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COVID-19 caused by the Omicron variant in lung transplant recipients: a single center case series
A new study investigates the risk factors for developing severe disease in lung transplant patients as a result of the Omicron variant of Covid-19.
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Probiotic supplementation may help reduce chemotherapy side effects in breast cancer
A new study shows that probiotics with seven strains have a potential effect in patients with breast cancer, especially in the improvement of common chemotherapy-related side effects such as fatigue and nausea.
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Researchers reveal how fungi ‘manipulate’ the course of tumors
In pancreatic ductal adenocarcinoma (PDA), the abnormal colonization of fungal communities has become a research hotspot. New research indicates that Malassezia is not only a ’marker’ in the tumor microenvironment but also a potential driver of cancer development.
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Novel point of attack to combat dangerous tropical diseases
Researchers have compiled a high-precision inventory of the membrane proteins of cell organelles of the African sleeping sickness pathogen, offering hope for new treatment approaches for dangerous tropical diseases.
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Scientists engineer antibody against flu with sticky staying power
Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The new molecule combines the specificity of a mature flu fighter with the broad binding capacity of a more general immune system defender. Source: NIAID Colorized transmission ...
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Monoclonal antibody nirsevimab provides strong protection against severe RSV in infants
Nirsevimab, a monoclonal antibody, is highly effective in real-world conditions at preventing severe respiratory syncytial virus (RSV) infections in infants, suggests a meta-analysis.
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siRNA plus nanovaccine yields stable functional cure for chronic hepatitis B
Researchers have developed an innovative therapy for chronic hepatitis B, synergistically combining their proprietary ferritin nanoparticle-preS1 (Ferritin-NP-preS1) therapeutic vaccine with a preclinically validated HBV-specific siRNA.
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Chiral phytovirucide targets viral Nia protein to inhibit proliferation
A new study focuses on the search for small molecules to target the Nia protein of Potato virus Y (PVY), one of the most economically destructive viruses affecting Solanaceous crops such as potatoes, peppers, and tomatoes.
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Global study finds single-dose baloxavir reduces household influenza transmission
A landmark study reveals that a single oral dose of baloxavir marboxil (baloxavir) significantly reduces the transmission of influenza within households, marking a major advancement in influenza management.
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Transatlantic collaboration to develop therapeutic for Crimean-Congo Hemorrhagic Fever
A new transatlantic collaboration will look to develop an affordable and accessible monoclonal antibody therapeutic for Crimean-Congo Hemorrhagic Fever Virus (CCHFV), which could treat and protect thousands of people globally.
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The very first structural images of a tuberculosis-fighting virus
Scientists have used advanced imaging techniques to provide a detailed look at how a tiny virus, known as a phage, invades Mycobacteria. The research could pave the way toward phage-based treatments for antibiotic-resistant mycobacteria.