All Disease Treatment & Prevention articles – Page 4
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NewsInfant gut bacteria may be the key to preventing asthma and allergies
A study shows that children are less likely to develop allergies and asthma if, as infants, they are colonized with certain bifidobacteria that produce a substance in the gut - a so-called metabolite - that dampens immune responses to allergens.
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NewsGut bacteria molecule boosts lung cancer treatment response
Researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.
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NewsNew study explores therapeutic potential of CRISPRCas3 genome-editing system
Scientists working on the genetic disease transthyretin amyloidosis evaluated the efficacy of the CRISPR–Cas3 system in safely achieving a permanent reduction of transthyretin (TTR) production through genome editing of the TTR gene.
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NewsWhen a virus releases the immune brake: New evidence on the onset of multiple sclerosis
A study investigating the links between Epstein-Barr virus and multiple sclerosis shows that EBV can interfere with the control of B cells. One viral protein mimics a crucial “approval” signal that B cells usually require from other immune cells. Self-reactive B cells can then survive even when they should be shut down.
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NewsNew mechanism links Epstein-Barr virus to MS
Scientists investigating the links between the Epstein-Barr virus and multiple sclerosis show that when the immune system fights EBV, certain T cells – which normally attack the virus – can also react to a protein in the brain called Anoctamin-2 (ANO2), a phenomenon called molecular mimicry.
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NewsGenetic risk factor and viral infection jointly contribute to MS
One of the leading triggers for multiple sclerosis (MS) is an infection with the Epstein-Barr virus. However, certain gene variants also play an important role. Researchers have shown that it is the molecular interaction between environmental and genetic risk factors that ultimately triggers the disease.
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NewsProbiotic living microneedles designed by interbacterial competition for accelerated infected wound healing
Probiotic therapy offers a promising strategy for chronic infected wound management. Inspired by bacterial competitive interactions, researchers developed a multifunctional microneedle (MN) platform to overcome the limitations of weak competitiveness and poor penetration across biofilm barriers.
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NewsNew test could help pinpoint IBD diagnosis, study finds
A test that rapidly detects signs of inflammatory bowel disease (IBD) in stool samples could improve future diagnosis and monitoring of the condition, a study suggests. The luminescent reporter lights up when it detects a molecule linked to gut inflammation.
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NewsNew hypothesis links HPV E6 and SARS‑CoV‑2 spike proteins to reduced p53 activity
Scientists have proposed a hypothesis suggesting that virally encoded proteins such as HPV-E6 or SARS-COV-2 Spike may cooperate in suppressing host defenses including tumor suppressor mechanisms involving p53.
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NewsInjectable hydrogel-mediated co-delivery of oncolytic adenovirus and melphalan for retinoblastoma control and vision preservation
The collagen-based hydrogel enabled controlled oncolytic adenovirus and melphalan release and sustained retention. This approach eradicated retinoblastoma tumors and restored normal ocular structure and visual function following intravitreal administration.
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NewsGut bacteria protect mice with influenza A from bacterial pneumonia, study finds
Select gut bacteria protect mice against post-influenza virus secondary bacterial pneumonia, according to a study which sought to define whether intestinal bacteria influenced some individuals’ vulnerability to secondary bacterial infections following primary respiratory viral infection.
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NewsA simple blood test can predict Crohn’s disease years before symptoms appear
Researchers have shown a blood test can predict Crohn’s disease years before symptoms appear, opening the doors to early diagnosis and potentially prevention. The test measures a person’s immune response to flagellin, a protein found on gut bacteria.
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NewsChanges in genetic structure of yeast lead to disease-causing genomic instabilities
Researchers studying a yeast model have discovered that the loss of heterochromatin can kickstart genetic changes, potentially resulting in the development of diseases like cancer.
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NewsClinical trial in Ethiopia targets the trachoma scourge
A new study documents the outcomes of an evaluation of fluorometholone as adjunctive medical therapy for trachomatous trichiasis surgery, part of an initiative to better prevent blindness and improve quality of life for those affected.
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NewsWhat causes some people’s gut microbes to produce high alcohol levels?
A study of people with a rare condition known as auto-brewery syndrome has found a link between gut microbes and symptoms of intoxication, pointing to new treatment strategies.
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NewsPlastic particles can increase intestinal inflammation
Researchers investigating a possible link between the rising number of people with chronic inflammatory bowel disease and the increasing exposure to micro- and nanoplastics show that plastic particles influence the immune cells and the intestinal microbiome and can thus increase inflammation.
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NewsGut bacteria changes at the earliest stages of inflammatory bowel disease
People newly diagnosed with the most common IBD subtypes, Crohn’s disease and ulcerative colitis, lose beneficial anaerobic bacteria that help with digestion of complex carbohydrates. Patients instead experience a rise in oxygen-tolerant bacteria from the mouth that travel in the gut.
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NewsOral bacterium tied to disability severity in multiple sclerosis
A research team has conducted a study with findings that suggest a potential association between the relative abundance of Fusobacterium nucleatum (F. nucleatum), a bacterium found in the mouth, and disease severity in multiple sclerosis (MS) patients.
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NewsResearch reveals how ancient viral DNA shapes early embryonic development
New research focuses on a viral transposable element called MERVL. This element becomes highly active for a short window of time when a mouse embryo reaches the 2-cell stage – the point at which a fertilised egg has divided into two cells and switches on its own genome for the first time.
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NewsResearch links tumor bacteria to immunotherapy resistance in head and neck cancer
Two new studies reveal that elevated levels of bacteria in the tumor microenvironment suppress immune response, driving resistance to immunotherapy in patients with head and neck squamous cell carcinoma.