More USA & Canada News – Page 2
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NewsCARB-X to support investigation of Exhalon’s breath-based lower respiratory tract infection testing platform
CARB-X has awarded Exhalon US$1M in seed funding to evaluate whether exhaled breath can be used as a non-invasive sample type to aid in the rapid and accurate diagnosis of lower-respiratory tract infections (LRTIs).
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NewsStudy suggests that chlorine treatment may impact the risk of legionnaires’ disease
Preliminary results of a nationwide study suggest that the disinfectant used to treat water before it is distributed through pipes may impact the incidence of Legionnaire’s disease in certain parts of the country.
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NewsHow did Bronze Age plague spread? Ancient sheep might solve the mystery
Researchers have found the first evidence of a Bronze Age plague infection in a non-human host. The scientists discovered Y. pestis DNA in a 4,000-year-old domesticated sheep from Arkaim, a fortified settlement located in the Southern Ural Mountains of present-day Russia.
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NewsTuberculosis: Scientists develop novel drug candidate for combating resistant pathogens
Researchers have developed a promising new substance for targeting bacteria that cause tuberculosis. The team have produced a compound that inhibits the pathogens’ ability to produce energy and causes them to die.
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NewsOld molecules show promise for fighting resistant strains of COVID-19 virus
SARS‑CoV‑2 continues to mutate, with some newer strains becoming less responsive to current antiviral treatments like Paxlovid. Now, researchers have identified several promising molecules that could lead to new medications capable of combating these resistant variants.
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NewsNew study reveals how natural humic substances reshape soil carbon cycling and boost antibiotic resistance
Researchers have uncovered surprising links between natural humification processes in soil, carbon metabolism, and the spread of antibiotic resistance. Subtle shifts in the composition of humic substances can reshape microbial metabolism and alter the abundance of antibiotic resistance genes.
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NewsHow can nursing homes protect more patients from infections?
New US national guidance calls for full-time infection prevention staff; more training, support and vaccination for all staff; and partnerships with hospitals and public health agencies.
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NewsWhat are the new guidelines for infant hepatitis B vaccination?
Public health expert and infectious disease physician Janet A. Jokela comments after the Advisory Committee on Immunization Practices of the CDC voted to discontinue its decades-long recommendation for universal vaccination against hepatitis B beginning at birth.
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NewsMajor breakthrough against diabetes thanks to a microbial molecule that disarms inflammation
Researchers have uncovered a surprising ally in the fight against insulin resistance and type 2 diabetes: a microbial metabolite called trimethylamine. TMA, produced by gut bacteria from dietary choline can block a key immune pathway and improve blood sugar control.
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NewsDose of psilocybin, dash of rabies point to treatment for depression
Researchers used a combination of psilocybin and the rabies virus to map how – and where – the psychedelic compound rewires the connections in the brain. Specifically, they showed psilocybin weakens the cortico-cortical feedback loops that can lock people into negative thinking.
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NewsEngineered virus boosts immune response against glioblastoma in preclinical models
Researchers have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells. A single dose of the modified virus increased T-cell, natural killer cell, and myeloid cell responses in the tumor microenvironment and increased the overall survival in preclinical models.
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NewsDeep sea microbes yield up their engineering secrets
A biomatrix of tiny tubes of protein, known as cannulae, link cells of the thermal vent-dwelling archaeon Pyrodictium abyssi together into a highly stable microbial community. A study reveals new details about the elegant design of the cannulae and their method of construction.
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NewsSocial lives of viruses affect antiviral resistance
Interactions among viruses can help them succeed inside their hosts or impart vulnerabilities that make them easier to treat. Scientists are learning the ways viruses mingle inside the cells they infect, as well as the consequences of their socializing.
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NewsPostharvest apple immunity: a key factor in shelf life and fruit quality
New research sheds light on how the immune system of apple fruits interacts with their microbiomes during storage, playing a crucial role in maintaining fruit health and preventing spoilage.
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NewsChemists synthesize a fungal compound that holds promise for treating brain cancer
For the first time, chemists have synthesized a fungal compound known as verticillin A, which was discovered more than 50 years ago and has shown potential as an anticancer agent.
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News$1.9m grant supports research on chronic wounds
Assistant Professor Carolyn Ibberson at the University of Tennessee, Knoxville, has received a four-year, $1.9 million grant from the National Institutes of Health to support research on infections in chronic wounds.
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NewsResearchers identify bacterial enzyme that can cause fatal heart conditions with pneumonia infections
Researchers have identified a bacterial enzyme that may be the reason some people get heart complications with pneumonia, while others do not. Since enzymes create chemical reactions to help bacteria survive, grow, and sometimes attack tissues, zmpB could become a target for future therapies.
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NewsTo treat long COVID, we must learn from historical chronic illnesses, medical researchers say
Scientists and doctors have highlighted the importance of studying long COVID in the context of other post-acute infection syndromes or chronic illnesses. By analyzing historical accounts of other epidemics, researchers can gain important perspective on the effects of these chronic illnesses.
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NewsResearchers use ‘brain-on-a-chip’ to revolutionize fight against deadly encephalitis viruses
A transparent chip no larger than a stick of gum is helping scientists transform the way researchers study the human brain and develop treatments for some of the world’s deadliest viruses.
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NewsMental health conditions may heighten liver cancer risk in veterans due to increased hepatitis C
Mental health conditions, especially alcohol use disorder and post-traumatic stress disorder (PTSD), significantly increase the likelihood of developing liver cancer among U.S. veterans living with cirrhosis of any cause.