All Oral Microbiome articles
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NewsToothbrush produces electricity to battle plaque-making bacteria
A new toothbrush generates electricity through bristle movement to wage war on plaque-producing pathogens. The invention successfully reduced cavity- and periodontitis-causing bacteria better than regular mechanical brushing in the mouths of 115 volunteers over 3 months.
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NewsSAA1+ epithelial cells emerge as inflammatory ringleaders in periodontitis
Periodontitis is driven not only by bacteria but by how the gingival epithelium responds to them. This study maps that response at spatial and single-cell resolution, showing that a distinct serum amyloid A1 (SAA1)-high inflammatory epithelial subpopulation (SAA1+Epi) sits at the junctional epithelium, where subgingival plaque meets host tissue. ...
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NewsSelective inhibitory effects of docosahexaenoic acid on oral bacteria
Researchers evaluated four polyunsaturated fatty acids against five common oral bacteria, in single-species and mixed-species cultures, and conducted an 8-day randomized, placebo-controlled human mouth-rinse intervention, analyzing saliva by metagenomic sequencing and qPCR.
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NewsCranberry juice may be a boon for oral hygiene
Pure cranberry juice may do more than add a tart kick to the holiday table. In a small human study, it slowed dental plaque growth and reduced acid production, suggesting the fruit’s natural compounds could help protect tooth enamel.
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NewsHantavirus and the mouth: Review maps early oral warning signs, salivary clues, and precautions for dental teams
A review brings together the virology, epidemiology, clinical features, diagnosis, and treatment of human hantavirus infection and examines what each means for the mouth and for dental care.
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NewsPeople with long Covid have drastically different microbiome in their lungs and mouth
A study of more than 700 people has shown that those with long Covid have distinct differences in the mix of bacteria that live in their mouths and lungs, according to a study. The research also shows that these differences in the lung microbiome are linked to respiratory symptoms, as well as the cognitive and digestive problems known to occur in long Covid.
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NewsFusobacterium nucleatum drives immunosuppression and metastasis in TNBC
A new study identifies Fusobacterium nucleatum, a Gram-negative anaerobic bacterium associated with several cancers, as a key driver of tryptophan metabolic reprogramming, immunosuppression and lung metastasis in triple-negative breast cancer.
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NewsMXene-based hydrogel disrupt bacterial biofilms and reprogram immune cell metabolism to reverse bone resorption in periodontitis
Researchers have developed an injectable MXene-based composite hydrogel (GQM) for the treatment of periodontitis. The hydrogel consists of oxidized gellan gum (OG), quaternized chitosan (QCS), and magnesium-tannic acid modified MXene nanosheets (MTA-Mg).
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NewsMouth and gut microbes could help detect gastrointestinal cancers
Researchers report that by analyzing the make-up of oral microbes it may be possible to detect signals associated with stomach and colorectal cancer. These findings could lead to the development of new, less-invasive screening tests for gastrointestinal cancers.
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NewsMXene-based hydrogel disrupts bacterial biofilms and reprograms immune cell metabolism to reverse bone resorption in periodontitis
Periodontitis treatment not only requires effectively disrupting bacterial biofilms but also reshaping the local immune metabolic microenvironment to fundamentally break the vicious cycle of “infection-inflammation-bone resorption.”
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NewsNew therapy eliminates gum disease bacterium while preserving beneficial oral microbes
Researchers have created an innovative treatment for periodontitis that targets and eliminates harmful bacteria while preserving beneficial oral microbes essential for health.
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NewsImbalances in the oral microbiome linked to symptomatic hand osteoarthritis
Specific imbalances and disruptions to the oral microbiome have been linked to symptomatic hand arthritis. Study findings suggest that the microbial environment of the mouth may influence the disease process of hand arthritis.
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NewsThe respiratory microbiota in lung cancer: from dysbiosis and immunomodulatory networks to therapeutic opportunities
A comprehensive review reveals that dysbiosis of the respiratory microbiota drives lung cancer through four integrated pathways: oncogenic signaling, epigenetic/metabolic reprogramming, and chronic immune dysregulation.
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NewsCryo-EM helps identify the mechanisms of dental plaque formation
Researchers used cryo-electron microscopy to provide new insights into how Porphyromonas gingivalis causes plaque formation, revealing the 3D structure of Mfa pili, an arm-like filament which enables the bacteria to stick to host tissues and other microbes.
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NewsFoods containing heat-inactivated bacteria help reduce gum bleeding and improve inflammatory conditions
Continuous consumption of foods containing heat-inactivated Lactiplantibacillus pentosus can help reduce gum bleeding, report researchers. These postbiotic foods can improve inflammatory conditions and enhance gum health in adults with mild gingivitis.
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NewsCohabitating people share about a quarter of their gut and oral microbiota
People who live together share more oral and gut microbes with each other than with other people in their communities, according to a study. Researchers also found a link between more transmissible microbes and health, particularly type 2 diabetes.
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NewsFasting-mimicking diet reduces gum disease inflammation
A new study highlights how lifestyle modifications could be important alongside plaque control in managing gum disease. While fasting has been linked to reduced inflammation around the body, this is the first to establish a relationship with gum disease too.
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NewsWhat dental calculus can tell us about the oral microbiomes of ancient Japan
Microbe DNA from ancient dental calculus offers insights into the past oral microbiomes of the Japanese people, including the phylogeny of the periodontal disease-associated archaeon, Methanobrevibacter oralis.
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NewsDentistry researchers testing oral bacteria transplants to cure bad breath
To rebalance the oral microbiome and cure chronic halitosis, researchers are embarking on a first-of-its-kind experiment. These clinical trials transplant bacteria and other microbes from healthy donors into patients with halitosis. If successful, the healthy microbiota will crowd out the bad and patients’ bad breath will improve.
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NewsThe road to better health requires a map of the microbes in your mouth
Different parts of your mouth have entirely different bacterial communities, reveals a new microbial map. Researchers believe mapping these microbial niches will provide a census of the good bacteria present in the mouth and help to develop targeted therapies, such as probiotics, to maintain oral health and prevent disease.