All Pharmaceutical Microbiology articles
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NewsStudy confirms effectiveness of medicinal plant against SARS-CoV-2 virus
A study has revealed that galloylquinic acids extracted from the leaves of Copaifera lucens Dwyer, a tree endemic to Brazil primarily found in the Atlantic Forest, have a multi-targeted effect against SARS-CoV-2, the virus that causes COVID-19.
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NewsAncient, insect-targeting bacterial toxin may have implications for human health, agriculture, and drug discovery
Scientists have identified and characterized a new class of Streptomyces-produced toxins that are very distantly related to the deadly toxin that causes diphtheria, a serious and contagious infection, in humans.
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NewsNew cellular target prevents hepatitis E infection
To replicate, a virus must first enter a host cell. In a recent study, the researchers specifically investigated host cell processes required for successful HEV infection. In doing so, they identified the enzyme PIKfyve as a crucial factor for viral entry.
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NewsHow AI can help us count the ‘good’ viruses used in biopharmaceuticals
Researchers have developed a new methodology that uses artificial intelligence (AI) tools to identify and count target viruses more efficiently than previous techniques. The new approach can be used in applications such as pharmaceutical biomanufacturing.
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NewsComputational approach takes the guesswork out of drug development for Chagas disease
Researchers have established a computational protocol that could accelerate the development of more effective treatments for life-threatening parasitic infections such as Chagas disease, by enabling scientists to accurately identify reactions that can result in successful drug candidates without the need for trial and error.
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NewsScientists catch a fungal enzyme open for business
A new study shows that caspofungin, a widely used antifungal drug, works only when its target enzyme is active, pointing the way toward designing better treatments.
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NewsMillions suffering needlessly with curable hepatitis C, new analysis reveals
Millions of Americans are still battling potentially deadly hepatitis C even though they could be cured with antiviral drugs they are not receiving, a new analysis reveals.
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CareersQ&A: Meet Letters in Applied Microbiology junior editor Daniel Jesuwenu Ajose
We caught up with Daniel Jesuwenu Ajose, a Postdoctoral Research Fellow at the School of Biology and Environmental Sciences, University of Mpumalanga in South Africa, who is one of the newest Junior Editors with Letters in Applied Microbiology
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NewsResearchers uncover a ‘treasure trove’ of bioactive molecules in coral reefs
Researchers have found that coral reefs are home to a vast array of previously unknown bioactive metabolites — small biomolecules that have the biotechnological potential to provide the basis for new drugs, and a host of other products.
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NewsHIV treatment reduces accelerated biological ageing by nearly four years, landmark study shows
A major study presented at ESCMID Global 2026 has found that antiretroviral therapy (ART) reduces accelerated biological ageing in people with HIV (PWH) by nearly four years, a finding that could transform how clinicians monitor HIV treatment and long-term health outcomes.
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NewsStandard-dose antibiotic the ‘preferred choice’ of treatment for uncomplicated acute sinusitis
A study of patients with acute sinusitis found no major differences in measured outcomes between adults who received standard amoxicillin and amoxicillin‑clavulanate. Patients treated with amoxicillin‑clavulanate were at slightly higher risk of contracting secondary infections.
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NewsStudy finds blood pressure drug effective for treating antibiotic-resistant bacteria
A new study reports that a drug used to lower blood pressure could also be the basis of a promising new treatment for methicillin-resistant Staphylococcus aureus (MRSA). Candesartan cilexetil not only killed MRSA bacteria at different growth stages, but also reduced the formation of biofilms.
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NewsHong Kong’s waters at risk from over-the-counter drug pollution
A recent study of Hong Kong’s river and estuary systems has uncovered an overlooked major source of water pollution: common over-the-counter (OTC) drugs. Accessible, everyday OTC drugs accounted for up to 85% of pharmaceutical pollution in these waters during the wet season.
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NewsSelf-propulsion or slow diffusion: How bacteria, cells, and colloids respond to stimuli
One enables them to quickly leave an environment; the other helps them move toward where they are needed. In microorganisms, as well as in artificial structures, these are the movements triggered in response to incoming and outgoing signals.
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NewsShorter antibiotic courses show similar outcomes to longer use for some pneumonia patients
A multicenter target trial emulation found that for eligible patients hospitalized with community-acquired pneumonia (CAP), health outcomes were similar whether they received a three- to four-day course of antibiotics or a course lasting five days or more.
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NewsScientists discover the antibacterial potential of ‘hero’ Korean skincare ingredient
Fans of Korean skincare may be familiar with ‘hero ingredient’ Madecassic acid for its skin-soothing properties, but researchers have revealed its greater potential for use in the battle against antibiotic resistance.
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NewsA smarter way to build vaccines: scientists harness AI to target emerging alphaviruses
Scientists have developed a new computational pipeline that could dramatically accelerate the development of vaccines against a group of mosquito-borne viruses known as alphavirus.
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NewsPueraria lobata decoction-derived vesicle-like nanoparticles reveal a novel mechanism for ulcerative colitis treatment
By simulating the traditional decoction process, researchers successfully isolated structurally intact GGD-PDVLNs from dried Pueraria lobata after boiling. These nanoparticles demonstrated remarkable stability in simulated gastric acid and intestinal fluids.
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NewsAstragalus polysaccharide-linked exosomes “wake up” latent HIV-1 by flipping a key cellular switch
“Shock-and-kill” strategies aim to reactivate latent virus so infected cells become visible to immune clearance or additional therapies. In a new study, researchers investigated whether exosomes could mediate HIV latency reversal after exposure to Astragalus polysaccharide (APS).
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NewsPhase I study for human monoclonal antibody for Lyme disease demonstrates safety, tolerability, pharmacokinetics
A Phase I clinical trial of a human monoclonal antibody discovered and developed for the prevention of Lyme disease in the U.S. was well tolerated and showed lasting serum concentrations in participants, according to data.