All Pharmaceutical Microbiology articles
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NewsNew research makes first broad-spectrum antiviral
A new study offers a promising path toward the development of the world’s first broad-spectrum antiviral (BSA), which could be deployed against a wide range of deadly viruses, including future pandemic threats.
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NewsCommon painkillers linked to antibiotic resistance
Ibuprofen and paracetamol are common over-the-counter medications that many of us reach for when we’re sick. But new research shows that these trusted staples are quietly fuelling one of the world’s biggest health threats: antibiotic resistance.
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NewsNew AI tool reveals how drugs kill tuberculosis
A new study offers a powerful AI-assisted method for uncovering exactly how TB drugs kill the bacteria, opening the door to smarter treatment combinations that could work faster.
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NewsArchaea can kill bacteria with new antibacterials
A first look into the molecular defenses of archaea highlights the importance of surveying diverse microbes to discover new types of antimicrobials.
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NewsResearchers use generative AI to design compounds that can kill drug-resistant bacteria
With help from artificial intelligence, researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).
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NewsTwo-dose therapy for S. aureus bloodstream infections on par with standard treatment
A clinical trial has found that the outcome of treating complicated Staphylococcus aureus bloodstream infections with two intravenous (IV) doses of the antibiotic dalbavancin seven days apart is just as good as daily IV doses of conventional antibiotics over four to six weeks.
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NewsScientists find a microbial molecule that restores liver and gut health
Researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure. The treatment may offer a new, non-toxic way to prevent and treat non-alcoholic fatty liver disease (NAFLD).
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NewsLignin is effective against viruses and bacteria
Lignin, a polyphenol, has antimicrobial activity against viruses and bacteria. An by-product from wood industry, lignin has potential as promising green alternative to synthetic antimicrobial agents for coating agents, packaging material, or surface disinfectants.
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NewsSeventy-year-old Parkinson’s drug shows promise against tuberculosis
A medication developed in the 1950s to treat Parkinson’s disease may offer a powerful new tool in the fight against tuberculosis. The study found that benztropine can dramatically reduce levels of TB-causing bacteria by boosting the body’s natural immune response.
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NewsResearchers discover all-new antifungal drug candidate in university greenhouse
A research team at McMaster University has discovered a new drug class that could someday lead to breakthrough treatments for dangerous fungal infections. The new molecules, dubbed coniotins, were isolated from a plant-dwelling fungus called Coniochaeta hoffmannii — the samples of which were collected from the McMaster ...
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NewsAI uncovers new antibiotics in ancient microbes
Researchers used artificial intelligence to identify previously unknown compounds in Archaea that could fuel the development of next-generation antibiotics.
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NewsChemical trick could turn losing malaria drug into a winner
A new generation of malaria drugs failed clinical trials, in part because they were hard to swallow. Chemists have remodeled their structures to make them more soluble, while maintaining their effectiveness against drug-resistant parasites.
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NewsNew hydrogel-based treatment accelerates infected wound healing and balances skin microbiota
A novel ε-poly-L-lysine-loaded sodium-alginate/gelatin hydrogel (PSG15) has shown exceptional promise in accelerating the healing of infected wounds. The injectable hydrogel delivers antibacterial properties while regulating macrophage polarization and stabilizing the skin microbiota.
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NewsMaple compound offers new way to fight tooth decay
A new study highlights the potential of using a natural compound from maple to combat the bacteria responsible for tooth decay: Streptococcus mutans. Epicatechin gallate is a powerful and safe alternative to traditional plaque-fighting agents.
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NewsRevealed: New vaccine target to block malaria transmission
Researchers have visualised a key protein complex in malaria parasites for the first time, uncovering a new target for next-generation vaccines that could help stop the disease from spreading.
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NewsAnti-neuroinflammatory natural products from isopod-related fungus now accessible via chemical synthesis
Herpotrichone is valued for its ability to suppress inflammation in the brain and protect nerve cells, but could only be obtained in minute quantities from fungi that are symbiotic with isopods. Researchers have succeeded in chemically synthesizing this rare natural product.
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NewsNew drug combo outperforms Tamiflu in fighting flu (and chocolate is the key)
Scientists have unveiled a new drug pairing - including a compound found in chocolate - that outperforms Tamiflu, the most widely used anti-influenza medication, against even the deadliest flu strains, including avian and swine flu.
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NewsResearchers debunk long-standing concern about flu treatment in children
Researchers have debunked a long-standing theory about oseltamivir, known as Tamiflu. Oseltamivir treatment during flu episodes was associated with a reduced risk of serious neuropsychiatric events, such as seizures, altered mental status and hallucination.
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NewsWhy killer cells can lapse into ‘exhausted’ CD8+ T cells that no longer can stem disease
In a detailed study of exhausted T cell subsets researchers show that a transcriptional repressor called Gfi1 is a key regulator of the subset formation of exhausted CD8+ T cells and may offer a key to reducing exhaustion.
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NewsResearchers develop bacterial cellulose-based dressing for advanced burn wound care
Scientists have developed an innovative bacterial cellulose (BC)-based hemostatic dressing that enables rapid and sustained bleeding control.