All Pharmaceutical Microbiology articles
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NewsUnique bond identified as key to viral infection speed
Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, but new research reveals a deliberate imbalance in their shape that helps them infect their hosts.
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NewsOpioid use linked to higher risk of C. difficile infection
New research from the University of Georgia suggests that opioid use could make patients more vulnerable to infections. The meta-analysis examined four studies of almost 120,000 patients. The researchers found that about 31% of patients who were prescribed and taking opioids caught C. diff, compared to 17% of patients who weren’t using them.
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NewsCloves and miswak: Antimicrobial effects of Syzygium aromaticum and Salvadora persica against common pathogens in vitro
Clove essential oil (CEO) derived from Syzygium aromaticum and miswak (Salvadora persica) contains bioactive compounds with antimicrobial properties. This study aimed to evaluate the in vitro antimicrobial efficacy of CEO, miswak, and their combination against key peri-implantitis pathogens.
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NewsNew method to accelerate vaccine and drug development for norovirus
Researchers have developed a simple and efficient system for understanding the functions of specific norovirus genes, providing new avenues for developing antivirals and vaccines.
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NewsTuberculosis: Scientists develop novel drug candidate for combating resistant pathogens
Researchers have developed a promising new substance for targeting bacteria that cause tuberculosis. The team have produced a compound that inhibits the pathogens’ ability to produce energy and causes them to die.
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NewsOld molecules show promise for fighting resistant strains of COVID-19 virus
SARS‑CoV‑2 continues to mutate, with some newer strains becoming less responsive to current antiviral treatments like Paxlovid. Now, researchers have identified several promising molecules that could lead to new medications capable of combating these resistant variants.
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NewsNature’s 10: Ten people who shaped science in 2025
Microbiologists and scientists tackling infectious diseases are among Nature’s annual list of ten people at the heart of some of the biggest science stories of 2025.
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NewsEngineered virus boosts immune response against glioblastoma in preclinical models
Researchers have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells. A single dose of the modified virus increased T-cell, natural killer cell, and myeloid cell responses in the tumor microenvironment and increased the overall survival in preclinical models.
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NewsSocial lives of viruses affect antiviral resistance
Interactions among viruses can help them succeed inside their hosts or impart vulnerabilities that make them easier to treat. Scientists are learning the ways viruses mingle inside the cells they infect, as well as the consequences of their socializing.
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NewsPlant phenolic acids supercharge old antibiotics against multidrug resistant E. coli
Plant derived phenolic acids can dramatically enhance the activity of existing antibiotics against multidrug resistant E. coli, offering a promising new tool in the global fight against antimicrobial resistance.
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NewsStudy shows robust immune responses to H5N8 avian influenza vaccine
A new study shows that the MF59-adjuvanted A(H5N8) vaccine induced strong immune responses, including both functional antibodies and memory T-cell responses, against the vaccine virus, as well as against H5 viruses that have caused recent outbreaks in Europe and the United States.
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NewsChemists synthesize a fungal compound that holds promise for treating brain cancer
For the first time, chemists have synthesized a fungal compound known as verticillin A, which was discovered more than 50 years ago and has shown potential as an anticancer agent.
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NewsLight-sensitive microbial protein may herald new cancer therapies
Researchers used a mouse cancer model to show that tumors expressing Archaerhodopsin 3 shrink after exposure to green light.
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NewsCommon water pill may help HIV medicines work faster and reduce inflammation, early study suggests
Adding a readily available diuretic to standard HIV therapy appears to reduce circulating virus by four-fold, a new study shows. Researchers treated HIV-infected mice with human immune cells with first‑line antiretroviral therapy plus a long‑acting form of spironolactone.
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NewsResearchers rescue antibiotics from resistance using phototherapy
Researchers have used phototherapy to inhibit a protein in E. coli bacteria that makes them resistant to antibiotics. This new method, if proven safe and effective in living organisms, holds promise for rescuing the effectiveness of antibiotics that bacteria have become resistant to.
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NewsA viral fitness-constraint strategy exploits the structural and functional limitations of viral evolution
Researchers have revealed two innovative strategies for the development of durable and broadly neutralizing antibodies against SARS-CoV-2. Their study proposes the immune trajectory strategy and the viral fitness-constraint strategy.
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NewsCorticosteroid use does not appear to increase infectious complications in non-COVID-19 pneumonia
A systematic review and meta-analysis found that adjunct corticosteroids probably reduce short-term mortality in cases of severe pneumonia and acute respiratory distress syndrome and may reduce secondary shock in severe pneumonia.
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NewsUnder The Lens: Callum Cooper explores how bacteriophages could revolutionise medicine - and how we get to that point
In a compelling new video interview from Applied Microbiology International’s ‘Under the Lens’ series, Dr. Callum Cooper shares fascinating insights into one of medicine’s most promising frontiers: phage therapy.
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NewsNew guideline on pre-exposure and postexposure HIV prevention
Multiple pre-exposure (PrEP) and postexposure (PEP) treatments are now available to prevent HIV infection. An updated Canadian guideline contains 31 recommendations and 10 good practice statements to help clinicians and other health care professionals offer these options to patients.
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NewsGlobal Virus Network issues warning on the Marburg virus outbreak in Ethiopia
The Global Virus Network (GVN) has issued a statement on the newly confirmed outbreak of Marburg virus disease (MVD) in southern Ethiopia. This represents the country’s first documented outbreak of Marburg virus and raises urgent public health, research, and surveillance imperatives.