All Pharmaceutical Microbiology articles
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NewsMedications leave lasting mark on the gut microbiome, even years after use
Analysing stool samples and prescription records from over 2,500 Estonian Biobank participants, researchers found that the majority of drugs studied were linked to microbiome changes, with a substantial number of them also showing long-term effects detectable years after patients stopped taking them.
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NewsMicrobial allies: Bacteria help fight against cancer
An international team of scientists have discovered that microbes associated with tumours produce a molecule that can control cancer progression and boost the effectiveness of chemotherapy.
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NewsA ‘universal’ therapy against the seasonal flu? Antibody cocktail targets virus weak spot
Researchers report that a cocktail of antibodies protected mice—including those with weakened immune systems—from nearly every strain of influenza tested, including avian and swine variants that pose pandemic threats.
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NewsMushroom chemical teams with phages to deliver a one-two punch to MRSA
A chemical found in mushrooms can be teamed with bacteriophages to deliver a one-two punch to antibiotic-resistant infections, reveals a study presented at MLS Future Forum 2025.
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NewsNew antibiotic to fight superbug C. diff proves effective in clinical trial
As the effectiveness of antibiotics meant to fight the deadly superbug Clostridioides difficile wanes, a research team is seeing positive results of a new antibiotic on the scene – ibezapolstat – which is proving successful in fighting these infectious bacteria in clinical trials.
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NewsA survival kit for smallpox viruses
Scientists have discovered a previously unknown type of assembly chaperone during their analysis of poxviruses, and they have decoded its function in full detail. This is the first known chaperone that is not formed by a protein but by a nucleic acid — specifically RNA.
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NewsHeme-based sulfide sensing in bacteria: a new target for antibiotics
Heme binding to a bacterial transcription factor is critical for hydrogen sulfide (H₂S) signaling, a new study reveals. Heme binding promotes the reaction of H₂S with the transcription factor, leading to structural changes that can regulate stress tolerance in bacteria.
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NewsNew research makes first broad-spectrum antiviral
A new study offers a promising path toward the development of the world’s first broad-spectrum antiviral (BSA), which could be deployed against a wide range of deadly viruses, including future pandemic threats.
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NewsCommon painkillers linked to antibiotic resistance
Ibuprofen and paracetamol are common over-the-counter medications that many of us reach for when we’re sick. But new research shows that these trusted staples are quietly fuelling one of the world’s biggest health threats: antibiotic resistance.
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NewsNew AI tool reveals how drugs kill tuberculosis
A new study offers a powerful AI-assisted method for uncovering exactly how TB drugs kill the bacteria, opening the door to smarter treatment combinations that could work faster.
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NewsArchaea can kill bacteria with new antibacterials
A first look into the molecular defenses of archaea highlights the importance of surveying diverse microbes to discover new types of antimicrobials.
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NewsResearchers use generative AI to design compounds that can kill drug-resistant bacteria
With help from artificial intelligence, researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).
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NewsTwo-dose therapy for S. aureus bloodstream infections on par with standard treatment
A clinical trial has found that the outcome of treating complicated Staphylococcus aureus bloodstream infections with two intravenous (IV) doses of the antibiotic dalbavancin seven days apart is just as good as daily IV doses of conventional antibiotics over four to six weeks.
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NewsScientists find a microbial molecule that restores liver and gut health
Researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure. The treatment may offer a new, non-toxic way to prevent and treat non-alcoholic fatty liver disease (NAFLD).
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NewsLignin is effective against viruses and bacteria
Lignin, a polyphenol, has antimicrobial activity against viruses and bacteria. An by-product from wood industry, lignin has potential as promising green alternative to synthetic antimicrobial agents for coating agents, packaging material, or surface disinfectants.
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NewsSeventy-year-old Parkinson’s drug shows promise against tuberculosis
A medication developed in the 1950s to treat Parkinson’s disease may offer a powerful new tool in the fight against tuberculosis. The study found that benztropine can dramatically reduce levels of TB-causing bacteria by boosting the body’s natural immune response.
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NewsResearchers discover all-new antifungal drug candidate in university greenhouse
A research team at McMaster University has discovered a new drug class that could someday lead to breakthrough treatments for dangerous fungal infections. The new molecules, dubbed coniotins, were isolated from a plant-dwelling fungus called Coniochaeta hoffmannii — the samples of which were collected from the McMaster ...
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NewsAI uncovers new antibiotics in ancient microbes
Researchers used artificial intelligence to identify previously unknown compounds in Archaea that could fuel the development of next-generation antibiotics.
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NewsChemical trick could turn losing malaria drug into a winner
A new generation of malaria drugs failed clinical trials, in part because they were hard to swallow. Chemists have remodeled their structures to make them more soluble, while maintaining their effectiveness against drug-resistant parasites.
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NewsNew hydrogel-based treatment accelerates infected wound healing and balances skin microbiota
A novel ε-poly-L-lysine-loaded sodium-alginate/gelatin hydrogel (PSG15) has shown exceptional promise in accelerating the healing of infected wounds. The injectable hydrogel delivers antibacterial properties while regulating macrophage polarization and stabilizing the skin microbiota.