All Pharmaceutical Microbiology articles
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NewsAntiviral drug linked to SARS-CoV-2 mutations
Researchers have uncovered a link between an antiviral drug for COVID-19 infections called molnupiravir and a pattern of mutations in the SARS-CoV-2 virus.
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News Fast-track strain engineering for speedy biomanufacturing
The time and money required to engineer microbes to produce vital medicines and chemicals can be dramatically reduced with a new model-based method.
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NewsBlood cancer drug shows promise in killing ‘silent’ HIV cells
An existing blood cancer drug has shown promise in killing ‘silent’ HIV cells and delaying reinfections – a significant pre-clinical discovery that could lead to a future cure for the disease.
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NewsNewly engineered versions of bacterial enzyme reveal how antibiotics could be more potent
Researchers have generated the full inventory of mutations in the bacterial species Escherichia coli where the antibiotic rifampicin attaches to and disables an essential bacterial enzyme known as RNA polymerase (RNAP).
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NewsResearch uncovers possible monoclonal antibody treatment for Lassa fever
New research potentially points to an effective treatment for Lassa fever, a dangerous, often fatal disease common to much of West Africa but considered a major threat to global health.
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NewsCargo system inhibits E.coli biofilms with a fraction of the antibiotic dose
Scientists have designed a bacteria-targeted cargo system that is capable of inhibiting a quinolone resistant Escherichia coli biofilm using much lower levels of antibiotic. The researchers, from Koç University School of Medicine in collaboration with College of Science, Department of Chemistry, encapsulated the antibiotic ciprofloxacin into superparamagnetic iron oxide nanoparticles ...
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NewsResearchers decode new antibiotic clovibactin
Researchers have discovered and deciphered the mode of action of a new antibiotic, clovibactin, which is derived from a soil bacterium.
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NewsTests of new antifungal therapy for fungal meningitis are successful
Researchers have successfully tested a new oral formulation of the antifungal medication amphotericin among people who had HIV and cryptococcal meningitis - a common fungal infection around the brain.
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CareersI was transformed into a cartoon scientist honey bee!
Professor Les Baillie of Cardiff University has had a few unique experiences as a microbiologist, but becoming one of the stars of Betsy and Bertie Save The Bees is one that earned particular kudos from his granddaughter.
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NewsMolnupiravir dose of human effect size-equivalent blocks Covid transmission in ferrets
Two oral drugs provide equivalent therapeutic benefit in preventing severe COVID-19 in animal models, but only molnupiravir efficiently blocked SARS-CoV-2 transmission when administered at a human effect size-equivalent dose.
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NewsMonoclonal antibody shows promise for treating chronic hepatitis B and D infections
In a preclinical study, the potential of an engineered investigational human monoclonal antibody for the treatment of chronic hepatitis B and hepatitis D has been demonstrated.
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NewsChanges in gut microbiome alters rewarding effects of cocaine and cravings
Scientists have provided the first evidence that changes in the gut microbiome have significant effects on cocaine use and cravings after withdrawal.
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NewsNew HIV drug formulation could improve treatment outcomes for children worldwide
Researchers have confirmed the dosing, safety and effectiveness of a drug formulation designed for treating children with human immunodeficiency virus (HIV).
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News Researchers discover method to overcome antimicrobial resistance
Scientists have found a new class of molecules that inhibit the efflux pump of a bacterial cell.
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NewsScientists develop new solid-state storage method for biological materials
Scientists have developed a novel method for storing biological materials such as RNA and proteins in a solid-state, physically resembling a pill or a tablet, which dissolves in water for on-demand use.
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NewsResearchers uncover novel bacterial communication system to combat AMR
Using a sophisticated mass spectrometry technology developed at SMART and MIT, researchers have discovered that the enzyme RlmN is a stress sensor for reactive oxygen species (ROS) – highly reactive molecules which can cause damage to bacteria. Source: SMART AMR (L to R) SMART researchers Dr Cui Liang, ...
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NewsBioengineered yeast devouring agricultural waste could close carbon circle
Researchers report making modified yeast that can feed on a wider range of materials, many of which can be derived from agricultural by-products that we don’t use known as waste biomass.
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NewsPicolinic acid reveals its broad-spectrum antiviral abilities
Picolinic acid, a natural compound produced by mammalian cells, can block several disease-causing viruses such as SARS-CoV-2 and influenza A viruses, according to a new study.
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NewsFuture medicines could feature ingredients targeting bacterial motility and chemotaxis
Future medicines will probably be made up of a cocktail of compounds that inhibit different bacterial targets, including some that act against their motility and chemotaxis mechanisms, a new review suggests.
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NewsCyanotriazole compounds can rapidly cure trypanosome infections in mice
Scientists have identified a class of cyanotriazoles (CTs), which exhibit potent trypanocidal activity and lead to rapid clearance of parasites both in vitro and in mouse models of Chagas disease and human African trypanosomiasis.
