All Pharmaceutical Microbiology articles – Page 3
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NewsResearchers discover new way to customize living materials for tissue engineering, drug delivery and 3D printing
Researchers have revealed novel sequence-structure-property relationships for customizing engineered living materials (ELMs), enabling more precise control over their structure and how they respond to deformation forces like stretching or compression.
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NewsFirst success in overcoming gene therapy challenges deploys nanomachines loaded with wine ingredients
Scientists have demonstrated the ability to overcome significant challenges in gene therapy using adeno-associated virus vectors (AAV) by employing a novel smart nanomachine equipped with AAV.
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NewsNasal COVID-19 vaccine to enter US clinical trials
A nasal vaccine for COVID-19 is poised to enter a phase 1 clinical trial in the U.S. after an investigational new drug application from Ocugen, Inc. was approved by the Food and Drug Administration (FDA).
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NewsNIH-funded clinical trial will evaluate new dengue therapeutic
A clinical trial is testing an experimental treatment designed to help people suffering the effects of dengue. An investigational therapeutic will be administered to adult volunteers who have been exposed to a weakened strain that causes a mild form of the disease.
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NewsGene found in rough Salmonella Infantis variant offers drug target for variety of pathogens
A new study identifies a gene in a rough Salmonella Infantis variant that could offer a target for developing effective vaccines and therapeutic strategies, not only for Salmonella but other Enterobacteriaceae as well.
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NewsStudy yields new insights into the immunomodulatory properties of russula polysaccharides
A new study investigates the structural characteristics and immunomodulatory activities of polysaccharides extracted from Russula vinosa Lindblad using KOH, highlighting the potential of these polysaccharides for applications in pharmaceuticals and functional foods.
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NewsV-161: A breakthrough in the fight against antibiotic-resistant VRE infections
Researchers from Japan have identified V-161, a compound that inhibits Enterococcus hirae V-ATPase activity, disrupting Na+ transport and effectively inhibiting VRE growth.
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NewsScientists synthesize a promising mushroom-derived compound
Researchers have successfully developed the first method to synthesize inaoside A, a compound derived from the edible mushroom Laetiporus cremeiporus.
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NewsStudy of hemp microbiomes may lead to more sustainable farming methods
A new study of hemp microbes may help scientists create special mixtures of helpful microbes to make hemp plants produce more CBD or have better-quality fibers.
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NewsNew insights offer hope for developing antiviral therapeutics targeting mpox
New research provides novel perspectives on the biological function of G4s in the lifecycle of MPXV and offer potential avenues for developing antiviral therapeutics targeting mpox prevention and treatment.
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NewsScientists explain how a compound from sea sponge exerts its biological effects
Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor effects and also found to have anti-malarial effects. Now researchers have a better idea of how it works.
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NewsSmall antibody offers broad protection against influenza
Researchers have discovered an antibody-like molecule that can protect mice from various influenza viruses. The findings could pave the way for new treatments and the development of broader influenza vaccines.
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NewsCARB-X funds Peptilogics to develop a novel, broad-spectrum therapeutic to treat fracture-related infections
CARB-X will award Peptilogics US$3.3 million to develop and execute a workplan for its slow-release formulation of a novel, broad-spectrum therapeutic, zaloganan-CR, an engineered peptide intended for use in preventing infection after high-energy-traumatic bone injuries.
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NewsScientists advance nanobody technology to combat deadly Ebola virus
Researchers have developed the first nanobody-based inhibitors targeting the Ebola virus. Their small size allows them to access areas of the virus and human tissues that larger antibodies cannot.
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NewsCompound derived from Brazilian plant acts against parasite that causes visceral leishmaniasis
A compound derived from Nectandra leucantha, a tree native to southern Brazil (local names canela-seca or canela-branca), has the potential to be used to treat visceral leishmaniasis, a neglected tropical disease.
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NewsOvercoming resistance: McMaster researchers find new utility for old antibiotics
In a recent study, researchers found that zinc plays a vital role in how some of the world’s most dangerous bacteria resist antibiotics.
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NewsAs prevention strategy for sexually transmitted infections rolls out, experts highlight both promise and knowledge gaps
Real-world evidence demonstrates that the postexposure strategy of doxy PEP is reducing the rate of syphilis and chlamydia, but has had little to no effect on gonorrhea and needs close monitoring for signals of antibiotic resistance.
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NewsResearchers discovered replication hubs for human norovirus
Researchers have reported the discovery of replication hubs for human norovirus, which could lead to designing antiviral drugs to prevent, control or treat these infections.
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NewsTinkering with the ‘clockwork’ mechanisms of life
Scientists have successfully recreated and validated two distinct mechanisms that can program both the activation and deactivation rates of nanomachines in living organisms across multiple timescales.
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NewsNature’s instructions: How fungi make a key medicinal molecule
Scientists outline how they deciphered nature’s own instructions — namely, the genes of the mold Penicillium citrinum — to discover a previously unreported enzyme that catalyzes the creation of cyclopentachromone-containing compounds.