All Pharmaceutical Microbiology articles – Page 10
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NewsInsights into release of fungal toxin promise progress in treating infections
The toxin Candidalysin of the yeast Candida albicans is incorporated into an unusual protein structure during an infection, and researchers have now succeeded in deciphering the function of this unusual arrangement.
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NewsRevolutionary chronic wound treatment could help millions
A team of scientists has developed an effective treatment for preventing infection in chronic wounds involving the plasma (electrical gas) activation of hydrogel dressings to produce a unique mix of different chemical oxidants.
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NewsSteroid drugs used for HRT can combat E. coli and MRSA
New research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.
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NewsNew dual therapeutic strategy shows promise against multidrug-resistant salmonella
A new collaborative study discloses the discovery and application of a new therapeutic strategy to target the multidrug-resistant bacterium Salmonella enterica in vivo, with promising results. The results were published in Scientific Reports. Source: CDC/ Antibiotic Resistance Coordination and Strategy Unit Medical illustration of drug-resistant, nontyphoidal Salmonella sp. ...
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NewsResearchers open new leads in anti-HIV drug development, using a compound found in nature
Researchers have successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
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NewsLong-acting HIV treatment benefits adults with barriers to daily pill taking and adolescents with suppressed HIV
Long-acting, injectable antiretroviral therapy (ART) suppressed HIV replication better than oral ART in people who had previously experienced challenges taking daily oral regimens and was found safe in adolescents with HIV viral suppression.
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NewsFirst atom-level structure of packaged viral genome reveals new properties, dynamics
A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and drug targets, researchers report.
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NewsDrug-resistant tuberculosis responds rapidly to bedaquiline-based second-line therapy
Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens.
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NewsSpace-grown antiviral drug successfully brought back to earth in private Varda Space capsule
Space-grown crystals of an antiviral drug have been brought to earth following the successful recovery of the capsule from Varda Space Industries’ W-1 mission.
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NewsResearchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
A new class of antibiotics not only shows promise against a broad array of bacterial infections but can also evade the dreaded resistance that has been rendering our current generation of first-line antibiotics ineffective.
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NewsLong-acting HIV treatment demonstrates efficacy in people with challenges taking daily medicine as prescribed
Long-acting antiretroviral therapy (ART) with cabotegravir and rilpivirine was superior in suppressing HIV replication compared to daily oral ART in people who had been unable to maintain viral suppression through an oral daily regimen, according to interim data from a randomized trial. Source: NIAID Colorized transmission electron micrograph ...
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NewsLow-cost microbe can speed biological discovery
Researchers have created a new version of a microbe to compete economically with E. coli – a bacteria commonly used as a research tool due to its ability to synthesize proteins – to conduct low-cost and scalable synthetic biological experiments.
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News£1.8m grant to engineer microbial cell factories
A team of academics from Aston University and the University of Warwick has secured a £1.8m grant to engineer microbial cell factories to produce membrane proteins which will support future drug screening and sustainable chemical production.
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NewsNew molecular toolkit boosts useful molecule production from yeast communities
A new molcular toolkit consists of 15 different yeast strains that over-produce key cellular building blocks – amino acids and nucleotides – but lack the ability to make other building blocks.
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NewsFlu virus variants resistant to new antiviral drug candidate lose pathogenicity, study finds
Influenza A viruses with induced resistance to a new candidate antiviral drug were found to be impaired in cell culture and weakened in animals, a new study has found.
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NewsAiCuris and DZIF sign Collaboration and License Option Agreement
AiCuris Anti-infective Cures AG and the German Center for Infection Research (DZIF) have announced the signing of a collaboration and license option agreement.
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NewsMutating hepatitis viruses make drug treatment more difficult
Sofosbuvir and Ribavirin combination therapy efficiently decreased viral RNA in blood and stool in patients with chronic HEV infection, but variants that are associated with antiviral resistance emerged during treatment.
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NewsFungus yields different pathway to the same pharmaceutically important substance
Researchers analyze a fungal biosynthetic pathway and discover a capable enzyme.
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NewsScientists identify natural PLA2 inhibitor from marine fungus Aspergillus sp. c1
The identified marine fungus metabolite HN-001 ameliorates lipotoxicity by suppressing IRE-1α/XBP-1s axis and JNK pathway for MAFLD treatment with PLA2 as an upstream target.
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NewsCollaborative infectious disease research takes aim at bystander cells
Researchers examining disease infection in bystander cells were granted nearly $500,000 from the Chan Zuckerberg Initiative to advance their work.
