All Pharmaceutical Microbiology articles – Page 10
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News
Symbiosis between bacteria and toxic bird yields discovery of new antimicrobials
A research team has identified two new classes of active substances with antimicrobial properties from bacteria that live in symbiosis with a toxic bird.
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Study identifies potential targets for treatment of visceral leishmaniasis
Discovery of a novel class of proteins that help regulate the parasite’s essential cellular functions could lead to the development of more effective drugs against the disease. More than 3,500 new cases are notified each year in Brazil.
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Selfishness mechanism points way to optimizing inhibitors that fight antibiotic resistance
Resistance can be fought by targeting bacteria that are ’selfish’ with their antibiotic resistance tools, according to a new study.
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Zika virus offeres potential as treatment for brain cancer: review
Fourteen studies showed that Zika virus reduced cell viability, inhibited the growth and proliferation of glioma stem cells (GSCs), and decreased Bcl2 expression in central nervous system tumors, potentially enhancing chemotherapy and radiotherapy effects.
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Scientists discover series of SARS-CoV-2 mpro inhibitors for potential COVID-19 treatments
New research has identified a novel series of SARS-CoV-2 Mpro inhibitors that may lead to potential new COVID-19 treatments that, according to preclinical testing, effectively inhibits COVID-19 and synergizes with existing anti-COVID therapies.
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Trials show common cold medication significantly improved symptoms in less than two days
Applied Biological Laboratories will present results of a clinical trial which showed Biovanta significantly improved common cold symptoms including sore throat, cough, runny nose, congestion, chills, and sneezing in less than two days.
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Rates of a tick-borne parasitic disease are on the rise
Cases of babesiosis increased 9% per year, on average, between 2015 and 2022 and nearly half were co-infected with another tick-borne illness such as Lyme disease, according to a new study.
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Study identifies potential novel drug to treat tuberculosis
A new study demonstrates that a novel semi-synthetic compound can be derived from natural compounds to produce potent activity against Mycobacterium tuberculosis, including multi-drug resistant strains.
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Plant compound used in traditional medicine may help fight tuberculosis
A compound found in African wormwood — a plant used medicinally for thousands of years to treat many types of illness — could be effective against tuberculosis, according to a new study.
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New images of RSV may expose stubborn virus’s weak points
Using cryo-electron tomography, researchers have revealed details of molecules and structures essential to RSV’s form and function.
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High-throughput modular click chemistry synthesis of catechol derivatives to target Covid protease
Researchers performed high-throughput synthesis of catechol derivatives from the bioactive catechol-terminal alkyne scaffold A4, by using modular click chemistry, in a bid to target the Covid virus’s 3C-like protease (3CLpro).
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Scientists design new drug to fight malaria
Scientists have designed a new drug against malaria and identified its mechanism of action. MED6-189 is effective against drug-sensitive and drug-resistant P. falciparum strains in vitro as well as in a humanized mouse model.
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Careers
Farm gates and facial fungi: Tanu charts her journey towards commercialisation
AMI Global Ambassador for New Zealand Tanushree Gupta is bringing an antifungal product to market that will make a huge difference to the hundreds of farms affected by facial eczema - so here’s how it’s going.
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Study probes industrial scale lactoferrin production with synthetic biological systems
A new study explores the innovative technologies developed to increase lactoferrin production in order to meet market demand in food, pharma, and cosmetics.
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Study IDs novel small-molecule inhibitors of SARS-CoV-2 with chemical genetics
A new article discusses the identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics.
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Eradivir closes $10.25M Series A funding round for next stage of influenza therapeutic trials
Eradivir, a preclinical biotech company that develops antiviral therapeutics, has completed a $10.25 million Series A funding round which will be used to conduct a Phase 2a challenge study of its EV25 influenza treatment.
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Ten different pharmaceuticals detected in corals in the Gulf of Eilat
A new study has detected traces of 10 common medications in coral samples collected from both shallow and deep sites in the Gulf of Eilat. Sulfamethoxazole, an antibiotic used for respiratory and urinary tract infections, was found in as many as 93% of the sampled corals.
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Researchers identify new tools for anti-Acinetobacter drug development and AMR preparedness
Researchers have engineered a library of strains that can be used to develop new antibacterial compounds to help address antimicrobial resistance (AMR) in Acinetobacter baumannii bacteria.
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An antidiabetic helps the immune system recognize reservoirs of HIV
Metformin, a drug used to treat type 2 diabetes, could help deplete the viral reservoir and eliminate it entirely in people living with HIV who receive antiretroviral therapy, a new study reveals.
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Conscience announces top performers in open science challenge to design promising pan-coronavirus drugs
The nonprofit drug discovery biotech Conscience has released seven newly discovered promising early-stage molecules that could lead to a new treatment effective against all coronaviruses, not just SARS-CoV-2.