All Pharmaceutical Microbiology articles – Page 5
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NewsRice-grown chaga reveals genes behind valuable triterpenoids
New study links triterpenoid accumulation in Inonotus obliquus with rising expression of key biosynthetic genes, providing a genetic foundation for future work to improve sustainable production of Chaga-derived compounds.
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NewsBreakthrough for aquaculture: Oral vaccine protects fish from fatal nervous necrosis virus
A novel oral vaccine, that can be mixed into fish feed, provides an effective, practical and cost-effective method to protect fish from the highly deadly nervous necrosis virus.
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NewsBack in action: Researchers make drug-resistant bacteria vulnerable again
New findings show that disabling a single bacterial protein can restore vancomycin’s power against resistant bacteria – and point to a new strategy for overcoming antibiotic resistance.
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NewsMount Sinai scientists develop first fully human monoclonal antibody cocktail that protects against Nipah and Hendra viruses
New preclinical study demonstrates that a novel monoclonal antibody cocktail provides complete protection against lethal Nipah and Hendra virus infection.
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NewsProbiotic bacteria Lactobacillus rhamnosus alleviates diabetic nephropathy in rat models
A recent study demonstrates that the probiotic strain Lactobacillus rhamnosus exerts significant renoprotective effects rat models of diabetic nephropathy.
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NewsNew research makes critical discovery for the global fight against antibiotic resistance
A study has found that an unusual pairing of two commonly used antibiotics can kill and stop the spread of resistance in a highly drug-resistant bacterium, Pseudomonas aeruginosa.
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NewsLandmark study reveals ‘megacluster’ of bacterial genes behind arsenal of potent antibiotics
A newly discovered “megacluster” of genes in Streptomyces bacteria produces four new natural product antibiotics that work together to stop rival bacteria.
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NewsVeterinary review warns antibiotic resistance threatens vision in pets
A new review warns sight-threatening antibiotic-resistant eye infections are becoming a significant threat to vision in dogs, cats, and horses with multidrug-resistant bacteria becoming more common in referral veterinary settings.
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NewsProtective human antibodies target West Nile and related viruses
New research defines vulnerable sites on West Nile virus that could inform vaccine development, and highlight antibody candidates with prophylactic and therapeutic potential. They may also guide interventions for a wider group of encephalitic orthoflavivirus infections.
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NewsAlgae microbots take aim at bladder cancer
Tiny algae-based robots guided by magnets could improve bladder cancer treatment by boosting delivery of chemotherapy drugs into tumours. Tracked using real-time imaging, the miniature robots help drugs penetrate deep into tumour tissue while limiting damage to healthy cells.
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NewsAI unlocks the secrets of viruses: Birth of large protein structures for vaccine delivery
An international research team has succeeded in designing large-scale protein structures that faithfully replicate the self-assembly principles found in naturally occurring viruses, using artificial intelligence (AI).
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NewsA new HIV vaccine study reveals new hope—and new challenges—for aging patients
A new clinical trial demonstrates that novel vaccines can significantly boost T cells targeting and could contribute to curative approaches against HIV.
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NewsTherapeutic vaccine shows mixed efficacy in preventing head and neck cancer recurrence
Researchers explore the effectivity of new therapeutic cancer vaccine in preventing the recurence of human papillomavirus triggered cancers.
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OpinionBiopiracy in microbiology: Who owns nature’s resources?
A growing global debate over “biopiracy” is raising urgent questions for microbiologists, researchers, industry and policymakers alike — and Applied Microbiology International is calling on members to help shape the conversation. Biopiracy refers to the unauthorised or unethical use of biological materials — including seeds, plants, ...
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NewsStudy reveals 45 new toxins produced by bacteria associated with foodborne infections
Researchers have discovered 45 new toxins produced by Salmonella bacteria, some of which are associated with foodborne infections. The study shows that these substances primarily act in the competition among microorganisms for space and resources.
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NewsMetformin given during acute COVID-19 infection reduced risk of clinician-diagnosed long Covid by 50%
New findings from the ACTIV-6 randomized clinical trial provide important confirmation of prior clinical trial results that metformin, a widely available and inexpensive medication with an established safety record, reduced the risk of clinician-diagnosed long COVID when started during acute COVID-19 infection.
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NewsGLP-1s may alleviate depression in mice through the microbiome
Some people taking GLP-1 drugs for diabetes and obesity experience mental health benefits. In a mouse model study, researchers report that these improvements appear to result from gut microbiome changes that lead to an abundance of a microbe strain known to have a favorable effect on neurons related to stress.
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NewsResearchers test two treatments to protect against deadly cattle disease
As cases of a deadly cattle disease rise in Arkansas, researchers are testing two treatments they hope will help ranchers protect their herds. The disease is bovine theileriosis and is caused by the parasite Theileria orientalis Ikeda, carried primarily by the invasive Asian longhorned tick.
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NewsPlants could be used to grow medicines in space, study shows
Astronauts on long space missions may one day use plants to produce fresh stocks of medicines on demand. Researchers developed a simple method to grow and repeatedly harvest plant virus-based pharmaceuticals from plants under space-like conditions, without destroying the plants or generating large amounts of waste.
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NewsFlu drugs show promise against cognitive decline
A class of flu drugs may reduce cognitive decline and premature aging in people living with chronic viral infection. Scientists identified a new biological culprit: the degradation of protective sugar molecules in our bodies, known as glycans, that normally help keep inflammation in check.