All Pharmaceutical Microbiology articles – Page 5
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NewsScientists to eliminate bottlenecks to breakthroughs with a new synthetic biology robotics system
Researchers in UC Santa Barbara’s newly designated Biological Engineering (BioE) Department have received a significant boost from the U.S. Army, which awarded a $9.85 million grant to design and purchase state-of-the-art equipment.
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NewsPotential therapeutic target found to combat TB, a disrupted NAD(H) homeostasis
A study shows how Mycobacterium tuberculosis perturbs homeostasis of the high-energy molecule NADH and reprograms glycolysis in myeloid cells - highlighting glycolysis as a potential therapeutic target.
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NewsSilver nanoparticles guarantee antimicrobial safe-tea
Researchers at the Institute of Physical Chemistry of the Polish Academy of Sciences (IPC PAS) have demonstrated green tea-silver nanoparticles as a powerful tool against pathogens such as bacteria and yeast.
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NewsCancer therapy shows promise against tuberculosis
A promising new cancer therapy also appears extremely potent against one of the world’s most devastating infectious diseases: tuberculosis (TB).
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NewsIridescentBio bringing virtual high-throughput assays to antibody R&D
IridescentBio is a new techbio start-up that’s bringing creative chemistry, physics know-how and methods to the Biopharma R&D world. The team of four are building computational models in the cloud to provide forecasting superpowers for lab-based research and development of antibody therapeutics. IridescentBio’s modelling framework is already ...
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NewsNovel C. diff structures are required for infection and offer new therapeutic targets
Iron storage ‘spheres’ inside the bacterium C. diff — the leading cause of hospital-acquired infections — could offer new targets for antibacterial drugs to combat the pathogen.
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NewsTiny hinges bend the infection-spreading spikes of a coronavirus
Disabling those hinges could be a good strategy for designing vaccines and treatments against a broad range of coronavirus infections, including COVID-19.
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NewsBook scopes out marine natural compounds in search for anti-infective medicines
The latest volume of the Bentham Science book series, Frontiers in Antimicrobial Agents, scopes out the potential of marine natural compounds in the search for anti-infective medicines.
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NewsOne in five patients experience rebound COVID after taking Paxlovid, new study finds
While Paxlovid remains a ‘life-saving drug,’ researchers found that patients experiencing virologic rebound after treatment may remain contagious.
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NewsAntiviral treatment largely underused in children with influenza
Despite US national medical guidelines supporting the use of antiviral medications in young children diagnosed with influenza, a new study reports an underuse of the treatment.
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NewsYeast cells can produce drugs for treatment of psychotic disorders
An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.
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NewsStatins team up with azoles to battle fungal infections
Researchers evaluated the antifungal efficacy of the pitavastatin-azole combination in silkworm models, suggesting its potential as an effective clinical treatment.
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News Crowd-sourced potent SARS-CoV-2 antiviral lead compound announced by COVID Moonshot Consortium
More than 200 scientists and students, triggered by a Twitter appeal, have identified and developed novel compounds with excellent antiviral activity against a key enzyme of the SARS-COV-2 virus, the main protease (Mpro).
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NewsResearchers discover new method to inhibit cholera infection
A new study investigates a novel strategy for inhibiting the spread and infection of Vibrio cholerae, the bacteria responsible for the disease cholera.
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NewsUK lagging on availability of treatment for rare diseases, industry group warns
A group of companies developing innovative new medicines for rare diseases is calling for the UK to lead greater collaboration between stakeholders, and uptake of best practice to improve access to new treatments for patients.
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NewsDrugs targeting iron regulation could be the answer to antifungal resistance
Drugs targeting iron uptake mechanisms could prove vital in the fight against human fungal pathogens, a new review suggests.
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NewsBroad-spectrum antiviral candidate targets dengue and SARS-CoV-2
A broad-spectrum antiviral drug candidate, 2-thiouridine, that targets positive-strand RNA viruses has been identified and characterized.
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NewsTechnique restores the function of a human cell surface protein in yeast cells
Scientists report a technique that could promote the use of yeast as a convenient platform to study human proteins and develop new drugs.
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NewsGut microbiota-derived 7-DHC tackles circadian rhythm disorders and IBD
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract categorized into ulcerative colitis and Crohn’s disease. Currently, aminosalicylates, glucocorticoids, immunomodulating drugs, and biological agents are common strategies for the treatment of IBD. The efficacy of these therapies is limited, however, and they are ...
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News‘Subway map’ of Lyme disease pathways IDs potential treatment targets
Researchers have developed a genome-scale metabolic model of key metabolic activities of the bacterium that causes Lyme disease, successfully identifying two compounds that selectively target routes only used by Lyme disease to infect a host.
