All Pharmaceutical Microbiology articles – Page 7
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News
Researchers create new treatment and vaccine for flu and various coronaviruses
A team of researchers has discovered two new ways of preventing and treating respiratory viruses using nasal sprays.
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Researchers engineer ‘cat parasite’ Toxoplasma gondii to release therapeutic proteins in the human brain
In a breakthrough study by an international team of scientists, the ‘cat parasite’ Toxoplasma gondii was engineered to deliver drugs to the human brain.
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New study highlights scale and impact of long COVID
A wide range of biological mechanisms are involved in long Covid, including persistence of the original virus in the body, disruption of the normal immune response, and microscopic blood clotting, even in some people who had only mild initial infections.
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Super cally molecules take down tuberculosis
Researchers have identified and synthesised a group of molecules that can act against the cause of tuberculosis in a new way. The callyaerins act against TB by employing a fundamentally different mechanism compared to antibiotic agents used to date.
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‘Russian doll’ packaging could boost drug delivery
Researchers have developed a new technology that lets them create compartments within compartments on the nanoscale, which can mean timing drug release for maximum effect at the site where it’s most needed.
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Chinese medicinal fungus shows promise in treating idiopathic pulmonary fibrosis
A recent study from China has reported that Cordyceps sinensis (CS), a traditional Chinese medicinal fungus, can ameliorate idiopathic pulmonary fibrosis (IPF) in mice by inhibiting mitochondrion-mediated oxidative stress.
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Exploratory analysis associates HIV drug abacavir with elevated cardiovascular disease risk in large global trial
Current or previous use of the antiretroviral drug (ARV) abacavir was associated with an elevated risk of major adverse cardiovascular events (MACE) in people with HIV, according to an exploratory analysis from a large international clinical trial primarily funded by the National Institutes of Health (NIH). There ...
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Dual action antibiotic could make bacterial resistance nearly impossible
A new antibiotic that works by disrupting two different cellular targets would make it 100 million times more difficult for bacteria to evolve resistance, according to new research
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New agent effective against drug-resistant malaria parasites
Scientists have developed a promising new antimalarial agent, DIF-1(+3), which is a derivative of Dictyostelium differentiation-inducing factor-1 (DIF-1).
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Isolated viral load test may generate false positive results for people using long-acting PrEP
A single laboratory-based HIV viral load test used by U.S. clinicians who provide people with long-acting, injectable cabotegravir (CAB-LA) HIV pre-exposure prophylaxis (PrEP) did not reliably detect HIV in a multi-country study.
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Peptide cocktails could be key to fighting antibiotic resistance
A new study highlights the potential of random antimicrobial peptide mixtures to significantly reduce the risk of resistance evolution compared to single peptides, emphasizing the need for innovative solutions to outpace bacterial resistance and safeguard health.
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Expiring medications could pose challenge on long space missions
Medications commonly used by astronauts aboard the International Space Station might be ineffective or harmful on a multi-year mission to Mars, a new study suggests.
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New drug target identified for diseases associated with leukemia-causing virus
Researchers have found a new target for treating diseases associated with human T-cell leukemia virus type 1 (HTLV-1). Blocking kinases, which regulate cellular functions, leads to cell death caused by the degradation of the protein Tax.
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Scientists pinpoint new drug target for RSV
Scientists have discovered how the dangerous Respiratory Syncytial Virus (RSV) defuses our immune response and, in doing so, they have pinpointed an exciting new target for drug developers.
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Llama nanobodies deliver breakthrough in building HIV immunity
Scientists have developed a new antibody therapy that can neutralize a wide variety of HIV-1 strains. They found success in an unlikely source — llamas.
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FedEx opens first European Life Science Center in Veldhoven
Federal Express Corporation, the world’s largest express transportation company, has opened its first European Life Science Center in Veldhoven, the Netherlands. The specialised cooling facility opens global access for the healthcare industry.
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Harnessing big data helps scientists hone in on new antimicrobials
Scientists have detailed a new method of identifying antimicrobial enzymes from large datasets of bacterial proteins, which could provide a solution to antibiotic resistance.
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Careers
Drug discovery and a valuable chance to network: Ugochukwu Anieto on a fascinating experience at ASM 2024
Professor Ugochukwu Anieto of Texas A&M University reveals how AMI’s Scientific Event Travel Grant helped him to gather some fascinating insights on antimicrobial compounds at the recent ASM conference.
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Scientists pioneer comprehensive derivative synthesis method for developing new antimicrobial drugs
A method to screen a wide variety of drug candidates without laborious purification steps could advance the fight against drug-resistant bacteria.
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Scientists isolate amylase enzyme produced by indigenous bacteria from sugar factory waste
Experts in wastewater processing and treatment have isolated amylase-producing bacteria from the liquid waste of sugar local factories and optimized the production of the amylase enzyme.