All Pharmaceutical Microbiology articles – Page 7
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NewsSuperbugs in our food: a new hope for tackling drug resistance
Researchers highlight the potential of quorum sensing inhibitors (QSIs) as a novel approach to tackle Pseudomonas aeruginosa. The study explores the mechanisms of action of various QSIs and potential applications in food safety and healthcare.
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NewsStudy reveals how bacteria in microbiome medicine trigger tumor-killing cells
Microbiotica has presented new data on the mechanism of action of MB097, a clinical-stage drug candidate being developed as a co-therapy in combination with KEYTRUDA® (pembrolizumab) in patients with advanced melanoma.
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NewsScientists invent new drug candidates to treat antibiotic-resistant bacteria
Researchers designed a new family of antibiotics that’s a variation of an existing drug called vancomycin, which is used as a last resort for extremely ill patients. The new version of vancomycin targets, bonds to and renders inactive two different parts of a molecule on the surfaces of pathogenic bacteria.
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NewsPromising new class of antimalarial drugs discovered
A new study identifies an inhibitor of gene regulation that specifically kills the malaria pathogen. The chromatin remodeler PfSnf2L is a key regulator of genes that play an important role in various stages of the pathogen’s development.
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NewsScottish bio-tech company secures £3.4m investment
Scottish biotech engineering company uFraction8 has secured £3.4m in new investment following the completion of a funding round led by Foresight Group.
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NewsScientists uncover how bacterial resistance to synergistic drug treatments is arising
Scientists investigating the potential of combined and more powerful drug treatments have found that antimicrobial resistance to these is arising via the vitamin B2 synthesis pathway.
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NewsNew therapy may effectively control HIV in Uganda
Clinical trials showed an effective antiviral drug, known as lenacapavir, against HIV in Uganda, and has also been tested for drug resistance in different subtype strains.
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NewsGround-breaking technique deploys bacterium to deliver drugs directly to the brain
A landmark study using the nasal bacteria technique promises new treatments for neurological disorders by bypassing the blood-brain barrier.
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NewsNew modeling approach could help design antivirals for shape-shifting viruses
New research utilizes an innovative computational modeling approach to capture the complex and diverse shapes that viral proteins can adopt.
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NewsResearchers engineer biological reaction crucibles to rapidly produce proteins
Biomedical engineers have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.
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NewsFrom Spanish flu to today: how immune cells keep up with a changing virus
In a breakthrough for influenza research, scientists have discovered immune cells that can recognise influenza (flu) viruses even as they mutate, raising hopes for a longer-lasting vaccine and a universal protection against future flu pandemics.
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NewsBreakthroughs in TB vaccine and drug development pave way for global health advancements
An international team of researchers unveils groundbreaking progress in TB vaccine development and therapeutic innovations, offering hope to curb the disease’s devastating impact.
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NewsNew study uncovers key differences in allosteric regulation of cAMP receptor proteins in bacteria
A new study provides key insights into how bacterial cAMP receptor proteins (CRPs) respond differently to the ubiquitous signaling molecule, cyclic AMP (cAMP), challenging the assumption that structural similarity predicts functional behavior in allosteric proteins.
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NewsResearchers discover new way to customize living materials for tissue engineering, drug delivery and 3D printing
Researchers have revealed novel sequence-structure-property relationships for customizing engineered living materials (ELMs), enabling more precise control over their structure and how they respond to deformation forces like stretching or compression.
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NewsFirst success in overcoming gene therapy challenges deploys nanomachines loaded with wine ingredients
Scientists have demonstrated the ability to overcome significant challenges in gene therapy using adeno-associated virus vectors (AAV) by employing a novel smart nanomachine equipped with AAV.
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NewsNasal COVID-19 vaccine to enter US clinical trials
A nasal vaccine for COVID-19 is poised to enter a phase 1 clinical trial in the U.S. after an investigational new drug application from Ocugen, Inc. was approved by the Food and Drug Administration (FDA).
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NewsNIH-funded clinical trial will evaluate new dengue therapeutic
A clinical trial is testing an experimental treatment designed to help people suffering the effects of dengue. An investigational therapeutic will be administered to adult volunteers who have been exposed to a weakened strain that causes a mild form of the disease.
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NewsGene found in rough Salmonella Infantis variant offers drug target for variety of pathogens
A new study identifies a gene in a rough Salmonella Infantis variant that could offer a target for developing effective vaccines and therapeutic strategies, not only for Salmonella but other Enterobacteriaceae as well.
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NewsStudy yields new insights into the immunomodulatory properties of russula polysaccharides
A new study investigates the structural characteristics and immunomodulatory activities of polysaccharides extracted from Russula vinosa Lindblad using KOH, highlighting the potential of these polysaccharides for applications in pharmaceuticals and functional foods.
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NewsV-161: A breakthrough in the fight against antibiotic-resistant VRE infections
Researchers from Japan have identified V-161, a compound that inhibits Enterococcus hirae V-ATPase activity, disrupting Na+ transport and effectively inhibiting VRE growth.