All Pharmaceutical Microbiology articles – Page 4
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A repurposed FDA-approved drug shows promise in killing antibiotic resistant bacteria
A study of Acinetobacter baumannii employed an entirely new strategy to identify weaknesses specific to resistant bacteria and then target these weaknesses with an alternate drug. They found that fendiline kills the bacterium by targeting the essential lipoprotein trafficking pathway, which is weakened in antibiotic resistant bacteria.
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Research identifies new trigger accelerating antibiotic resistance
A new study shows that ciprofloxacin, a staple treatment for urinary tract infections, throws Escherichia coli (E. coli) into an energy crisis that saves many cells from death and speeds the evolution of full‑blown resistance.
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New source of natural antibiotics hidden within our own proteins identified
A team of scientists has identified a new type of antimicrobial peptides (AMPs) found in human proteins that are capable of selectively eliminating multidrug-resistant bacteria, particularly of the gram-negative type, responsible for serious hospital acquired infections.
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Computer-identified antiviral drug candidates confirmed by lab experiments
An interdisciplinary research team has identified two antiviral drug candidates effective against a wide range of viruses. The study demonstrates how combining computer-aided modeling with laboratory validation can speed up the development of new antiviral drugs.
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Light-controlled bacteria can tackle antibiotic resistance or become ‘bacterial robots’
A groundbreaking technique uses light-sensitive materials to control bacteria, allowing them to sense light and convert light energy into electrical signals across their membranes without the need for any genetic modification.
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Cannabis extracts show remarkable effectiveness against fungal pathogens
Two cannabis-derived compounds have shown remarkable effectiveness against fungal pathogens in laboratory tests, according to new research.
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Real-time 3D visualization of leech peptide reveals potent antibacterial and antibiofilm activity
Researchers have discovered a novel natural antimicrobial peptide, ‘Hirunipin-2,’ from the salivary glands of the medicinal leech using cutting-edge imaging technology, demonstrating that it has high potential as a new therapeutic effective against superbacteria.
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Student discovers long-awaited mystery fungus sought by LSD’s inventor
A student has found a long sought-after fungus that produces effects similar to the semisynthetic drug LSD, which is used to treat conditions like depression, post-traumatic stress disorder and addiction.
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Lavender and lemongrass oils effective against thrush infections, new research reveals
They may be more familiar as a room scent but a new study being presented at the Letters in Applied Microbiology ECS Research Symposium 2025 reveals that lavender and lemongrass essential oils are effective against thrush, even at low levels.
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Synthetic compound shows promise against multidrug resistance
Researchers have synthesized a new compound called infuzide that shows activity against resistant strains of pathogens. In lab and mouse tests, infuzide reduced bacterial populations, suggesting it might be useful as a new treatment for drug-resistant infections.
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Targeting malaria parasite’s protein control system could be key to innovative treatments
By inducing protein aggregation in Plasmodium falciparum, researchers have observed considerable disorders in protein homeostasis and a significant reduction in parasite growth.
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Yeast produces human DNase1 for the first time
The protein DNase1 is used to treat cystic fibrosis but it takes considerable effort and cost to produce it in immortalized hamster cells. Researchers have now produced it in yeast cells for the first time.
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Mirror molecules deliver a one-two punch to superbugs to fight infections
Researchers have created mirror-image molecules that both kill pathogens outright and rally the immune system—an advance aimed at the growing crisis of antimicrobial resistance.
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KIST develops multifunctional peptide that fights viruses and promotes wound healing
Researchers announced that they have developed a therapeutic substance with both antiviral and tissue regenerative properties, based on a peptide derived from natural sources.
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Uncovering the shield: gene duplication behind antifungal resistance in Madurella fahalii
Researchers used advanced genetic and biomolecular chemistry tools to uncover why itraconazole treatment fails against Madurella fahalii but not other Madurella species.
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Can gut microbes save patients from chemotherapy side effects?
Intestinal microbes that survive chemo can rid the gut of excess chemo drugs and produce a vitamin that helps to stem nausea, a new study reveals.
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Biosynthetic pathway discoveries mean we can halve the price of costly cancer drug
Researchers have identified the enzymes responsible for the two critical final steps in the biosynthetic pathway that makes the chemotherapy drug Taxol active as a drug, potentially opening it up to biotech based production.
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Researchers reveal how microbes can swim without a brain
Many microorganisms can move in a goal oriented way in liquids, despite the lack of a complex nervous system. New research explains the behaviour of microorganisms, and could also enable nanobots to move in a targeted manner.
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Common drugs can help viruses spread
JAK inhibitors are often prescribed for autoimmune diseases and inflammatory conditions such as rheumatoid arthritis, but scientists have found they also weaken the body’s natural defences against viruses.
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Combining laboratory techniques yields wealth of information about deadly brain tumors
In a new study, researchers injected into the tumor a virus aimed at killing glioblastoma cells. Surgeons took tumor tissue samples and ran them through multiple advanced laboratory techniques to demonstrate that even small tissue samples can yield additional insights.