All Pharmaceutical Microbiology articles – Page 4
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NewsIlluminated changes: Enhancing D-lactic acid output with UV irradiation
Researchers have developed a Komagataella phaffii (K. phaffii) yeast strain that can efficiently produce D-lactic acid, a raw material for pharmaceuticals and bioplastics, from methanol.
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NewsAI could accelerate protein engineering – key for developing new medicines
An AI approach developed by researchers from the University of Sheffield and AstraZeneca could make it easier to design proteins needed for new treatments.
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NewsLaunch of first-in-human clinical trial of next-generation rotavirus vaccine delivered via dissolvable microarray technology
Scientists have announced the first clinical trial of a novel rotavirus vaccine, CC24, delivered via dissolvable microarray technology, is now enrolling participants.
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NewsStudy highlights role of jaundice-associated pigment in protecting against malaria
New research suggests that a pigment that causes yellowing of the skin, or jaundice, may help protect people from the most severe consequences of malaria.
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NewsBroad-spectrum coronavirus drug developed through AI-enabled dynamic modeling
Multidisciplinary AI- and physics-driven modeling of the viral fusion process enables discovery of an orally available drug inhibiting infection with multiple coronaviruses.
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NewsResearchers discover protein necessary for SARS-CoV-2 to evade the body’s defenses
Researchers have identified a protein that plays a key role in helping SARS-CoV-2 hide from the body’s defenses by suppressing the production of viral double-stranded (dsRNA), leading to increased viral replication while limiting the body’s immune response.
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NewsEvolutionary model for antibiotic resistance reveals dose timing critical to care
The study that uses a “fitness seascape” to incorporate a patient’s dosage schedule into models that predict whether an infection will develop antibiotic resistance has found that inconsistent timing and missing early doses can lead to treatment failure.
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NewsGlobal action urgently needed to tackle antimicrobial resistance, experts warn
Scientists have called for urgent changes to the way new antibiotics are developed to address the growing problem of antimicrobial resistance (AMR). They outline the scientific, economic, and regulatory barriers that are slowing progress.
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NewsGreen light activates this antibiotic only where it’s needed
To make a more efficient antibiotic treatment, researchers have modified penicillin so that it’s activated only by green light. In early tests, the approach precisely controlled bacterial growth and improved survival outcomes for infected insects.
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NewsA repurposed FDA-approved drug shows promise in killing antibiotic resistant bacteria
A study of Acinetobacter baumannii employed an entirely new strategy to identify weaknesses specific to resistant bacteria and then target these weaknesses with an alternate drug. They found that fendiline kills the bacterium by targeting the essential lipoprotein trafficking pathway, which is weakened in antibiotic resistant bacteria.
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NewsResearch identifies new trigger accelerating antibiotic resistance
A new study shows that ciprofloxacin, a staple treatment for urinary tract infections, throws Escherichia coli (E. coli) into an energy crisis that saves many cells from death and speeds the evolution of full‑blown resistance.
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NewsNew source of natural antibiotics hidden within our own proteins identified
A team of scientists has identified a new type of antimicrobial peptides (AMPs) found in human proteins that are capable of selectively eliminating multidrug-resistant bacteria, particularly of the gram-negative type, responsible for serious hospital acquired infections.
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NewsComputer-identified antiviral drug candidates confirmed by lab experiments
An interdisciplinary research team has identified two antiviral drug candidates effective against a wide range of viruses. The study demonstrates how combining computer-aided modeling with laboratory validation can speed up the development of new antiviral drugs.
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NewsLight-controlled bacteria can tackle antibiotic resistance or become ‘bacterial robots’
A groundbreaking technique uses light-sensitive materials to control bacteria, allowing them to sense light and convert light energy into electrical signals across their membranes without the need for any genetic modification.
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NewsCannabis extracts show remarkable effectiveness against fungal pathogens
Two cannabis-derived compounds have shown remarkable effectiveness against fungal pathogens in laboratory tests, according to new research.
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NewsReal-time 3D visualization of leech peptide reveals potent antibacterial and antibiofilm activity
Researchers have discovered a novel natural antimicrobial peptide, ‘Hirunipin-2,’ from the salivary glands of the medicinal leech using cutting-edge imaging technology, demonstrating that it has high potential as a new therapeutic effective against superbacteria.
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NewsStudent discovers long-awaited mystery fungus sought by LSD’s inventor
A student has found a long sought-after fungus that produces effects similar to the semisynthetic drug LSD, which is used to treat conditions like depression, post-traumatic stress disorder and addiction.
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NewsLavender and lemongrass oils effective against thrush infections, new research reveals
They may be more familiar as a room scent but a new study being presented at the Letters in Applied Microbiology ECS Research Symposium 2025 reveals that lavender and lemongrass essential oils are effective against thrush, even at low levels.
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NewsSynthetic compound shows promise against multidrug resistance
Researchers have synthesized a new compound called infuzide that shows activity against resistant strains of pathogens. In lab and mouse tests, infuzide reduced bacterial populations, suggesting it might be useful as a new treatment for drug-resistant infections.
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NewsTargeting malaria parasite’s protein control system could be key to innovative treatments
By inducing protein aggregation in Plasmodium falciparum, researchers have observed considerable disorders in protein homeostasis and a significant reduction in parasite growth.