All Pharmaceutical Microbiology articles
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NewsBacterial trial fails to demonstrate early asthma prevention - prompting rethink of 'hygiene hypothesis'
A national clinical trial has found that treating young children with an oral bacterial extract did not reduce the risk of severe wheezing and respiratory illnesses that can precede asthma, potentially prompting researchers to rethink aspects of the hygiene hypothesis.
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NewsCommonly used cancer drugs boost MRSA antibiotics – new research
Scientists tested five anti-cancer drugs and revealed that four of them helped penicillin-type antibiotics to kill MRSA. These drugs interfere with the bacteria’s ability to make DNA, making the bacteria more vulnerable to the antibiotics.
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NewsKazakh researchers ID antiviral and anti-inflammatory compounds in native medicinal plants
Researchers have identified biologically active compounds with antiviral, antimicrobial, and anti-inflammatory effects in several plant species native to Kazakhstan, providing new chemical and experimental data on medicinal flora from Central Asia.
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NewsMosaic nanoparticles deliver broad-spectrum mucosal protection against diverse coronaviruses
Researchers have developed a novel “mosaic” nanoparticle vaccine platform that successfully penetrates the mucus barrier to deliver broad-spectrum mucosal protection against a diverse array of coronaviruses, including highly evasive SARS-like and MERS-like strains.
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NewsStudy sheds light on how bacteria assemble outer membrane proteins
Researchers analyzed the various conformations that a chaperone protein adopts while delivering unfolded outer membrane proteins to the assembly machinery.
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NewsCancer medication helps reduce SIV reservoir, increases hope for HIV cure
Researchers have provided the first proof-of-concept in a nonhuman primate model for eliminating HIV-infected cells with venetoclax, a clinically approved medication for cancer.
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NewsNew design strategy expands nanoparticle vaccine approach to influenza viruses
Research scientists have developed a blueprint for stabilizing key influenza proteins and using them to make next-generation vaccine candidates.
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NewsTraditional Chinese medicine compound shows promise against ischemic stroke by targeting the gut-brain axis
Researchers have uncovered new evidence that a polysaccharide derived from the traditional medicinal herb Astragalus membranaceus (Huangqi) can protect against ischemic stroke by acting through an unexpected route: the gut.
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NewsRECOVER-VITAL clinical trial finds no benefit of extended duration of PAXLOVID for Long COVID
Results from a clinical trial show that the antiviral drug, PAXLOVID, commonly prescribed to treat acute COVID-19, does not have an impact on Long COVID symptoms when compared to placebo.
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NewsReview explores the presence, fate, and effects of pharmaceutical compounds in soil and air
Pharmaceutical contamination in soil and air has become a critical environmental concern due to its widespread sources, complex behavior, and long-lasting ecological impacts.
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NewsResearchers clear major obstacle in genetic engineering of proteins
An unexpected discovery about tRNAs leads to tool that can drive faster, safer production of new medicines.
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NewsT cells are a powerful force against Zika virus
Scientists tested two Zika vaccines in a study that brings them one step closer to a “pan-orthoflavivirus vaccine”, which could teach T cells to fight several viruses at once.
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NewsFor Legionella bacteria, taking over a cell means playing by its rules
New research demonstrates how a protein produced by Legionella mimics the behavior of the host cell’s own proteins.
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NewsTuberculosis transmission may hold the key to prevention
Scientists have discovered the specific mechanisms that enable the bacteria responsible for tuberculosis to not only survive drying but also to generate mutations linked to antibiotic resistance.
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NewsMagnetotactic bacteria show potential for extending healthy lifespan
Recently, new research has demonstrated that the magnetotactic bacterium (MTB) Magnetospirillum magneticum can extended healthy organismal lifespan in a Caenorhabditis elegans model.
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NewsNew study reveals how neutrophils reach infection sites without damaging healthy tissue
Researchers discover how neutrophils, the body’s most abundant type of white blood cells, travel to infection sites without damaging healthy tissue.
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NewsEpidemiologist discusses Pennsylvania’s first measles deaths in 35 years
Epidemiologist Jennifer Horney highlights the importance of vaccinations after the deaths of two Pennsylvania residents – the first measles deaths in the state in 35 years.
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NewsYeast‑derived universal flu vaccine could someday replace yearly injections
Engineered baker’s yeast produces virus-like particles that protect mice against multiple influenza strains.
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NewsIdentification and characterization of anti-chikungunya virus compounds using a biosafe toolkit
A new study characterizes several novel anti-chikungunya virus compounds and highlights the potential of combining screening approaches with mechanistic analyses to explore new antiviral strategies against emerging viral pathogens.
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NewsPotential of antibody therapy in treating tick-borne diseases
A new study identifies multiple targets for antibodies that could open new paths toward treatments for Crimean-Congo hemorrhagic fever.