All Pharmaceutical Microbiology articles – Page 2
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NewsGenetic ‘Trojan horse’ selectively kills cancer cells linked to Kaposi’s sarcoma
A highly targeted gene therapy that could revolutionize treatment for cancers linked to a common herpesvirus harnesses an adeno-associated virus (AAV) to deliver a genetic “Trojan horse” into infected cells.
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NewsNew herpes virus–based vaccine could cure cancer in the future without side effects
The Herpes simplex virus is a widespread virus that often causes cold sores, and most people carry it. By removing a virulence gene, i.e. a gene that makes the virus harmful to humans, the herpes virus can be repurposed as a cancer vaccine.
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NewsPeptide study paves path toward new weapon against antibiotic-resistant bacteria
New research into antimicrobial peptides, small chains of amino acids able to damage bacterial cells, shows why some peptides are more effective at doing that and also why some cells are more vulnerable.
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NewsSummer studentship: Eoin probes medicine-microbiome interactions using in vitro gut model
Eoin McKernan reports back on his AMI-sponsored summer studentship which focused on the relationships between the gut microbiome and the metabolism of variable response drugs.
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News‘Alarming’ rise in newborn babies with antibiotic-resistant infections, researchers find
Researchers are calling for an urgent overhaul of diagnostic and treatment guidelines for infections in newborn babies, after a study revealed frontline treatments for sepsis are no longer effective to treat the majority of bacterial infections.
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NewsTwo-drug combination shows promise in helping heal chronic wounds
By adding small doses of a simple molecule called chlorate to standard antibiotics, researchers foundthe combination proved 10,000 times more effective at killing bacterial cells in the lab than single-drug antibiotics.
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NewsOkinawan marine sponges yield promising treatment for leishmaniasis
A family of compounds called onnamides shows remarkable potential against the parasite that causes a neglected tropical disease.
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NewsMagic mushrooms invent active compound twice
A study shows that fungi have developed the ability to produce psilocybin at least twice independently of each other. While Psilocybe species use a known enzyme toolkit for this purpose, fiber cap mushrooms employ a different biochemical arsenal – and yet arrive at the same molecule.
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NewsBird flu outbreak in house cats: high-risk but survival possible
Cats can survive bird flu if they receive early care and antiviral treatment with oseltamivir and need not be euthanized in every case, a new study shows.
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NewsNew phenolic bisabolane sesquiterpenoids discovered from the marine-derived fungus Aspergillus sydowii
Three new phenolic bisabolane sesquiterpenoids (PBS) derivatives (±)-aspersydonol A (1a/1b) and aspersydonol B (2), along with 12 known analogues, have been isolated from the marine-derived fungus Aspergillus sydowii LF51.
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NewsMicrobiotica announces completion of recruitment in its international phase 1b trial of microbiome co-therapy
Microbiotica, a clinical-stage biopharma company developing a pipeline of oral precision microbiome medicines called live biotherapeutic products (LBPs), announces that patient recruitment is complete in its advanced melanoma (MELODY-1) trial.
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NewsMedications leave lasting mark on the gut microbiome, even years after use
Analysing stool samples and prescription records from over 2,500 Estonian Biobank participants, researchers found that the majority of drugs studied were linked to microbiome changes, with a substantial number of them also showing long-term effects detectable years after patients stopped taking them.
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NewsMicrobial allies: Bacteria help fight against cancer
An international team of scientists have discovered that microbes associated with tumours produce a molecule that can control cancer progression and boost the effectiveness of chemotherapy.
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NewsA ‘universal’ therapy against the seasonal flu? Antibody cocktail targets virus weak spot
Researchers report that a cocktail of antibodies protected mice—including those with weakened immune systems—from nearly every strain of influenza tested, including avian and swine variants that pose pandemic threats.
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NewsMushroom chemical teams with phages to deliver a one-two punch to MRSA
A chemical found in mushrooms can be teamed with bacteriophages to deliver a one-two punch to antibiotic-resistant infections, reveals a study presented at MLS Future Forum 2025.
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NewsNew antibiotic to fight superbug C. diff proves effective in clinical trial
As the effectiveness of antibiotics meant to fight the deadly superbug Clostridioides difficile wanes, a research team is seeing positive results of a new antibiotic on the scene – ibezapolstat – which is proving successful in fighting these infectious bacteria in clinical trials.
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NewsA survival kit for smallpox viruses
Scientists have discovered a previously unknown type of assembly chaperone during their analysis of poxviruses, and they have decoded its function in full detail. This is the first known chaperone that is not formed by a protein but by a nucleic acid — specifically RNA.
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NewsHeme-based sulfide sensing in bacteria: a new target for antibiotics
Heme binding to a bacterial transcription factor is critical for hydrogen sulfide (H₂S) signaling, a new study reveals. Heme binding promotes the reaction of H₂S with the transcription factor, leading to structural changes that can regulate stress tolerance in bacteria.
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NewsNew research makes first broad-spectrum antiviral
A new study offers a promising path toward the development of the world’s first broad-spectrum antiviral (BSA), which could be deployed against a wide range of deadly viruses, including future pandemic threats.
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NewsCommon painkillers linked to antibiotic resistance
Ibuprofen and paracetamol are common over-the-counter medications that many of us reach for when we’re sick. But new research shows that these trusted staples are quietly fuelling one of the world’s biggest health threats: antibiotic resistance.