All Bacteriophages articles
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NewsA built-in ‘hairpin’ prevents rogue CRISPR RNAs
A new study reveals that many CRISPR-Cas13 systems utilize an RNA to prevent the formation of extraneous CRISPR RNA. With the first repeat, this protective RNA forms a stable structure resembling a hairpin. It points to a remarkable case of convergent evolution.
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NewsHow cholera bacteria swap defenses against viruses
To survive viral attack, bacteria equip themselves with antiviral immune systems. Vibrio cholerae carries a large genetic element called a sedentary chromosomal integron (SCI). A new study investigates whether the SCI might capture gene cassettes from genetic material entering the cell from the outside.
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NewsVirus-inspired DNA needle could pave the way for better medicines
Researchers have developed a microscopic DNA needle that delivers molecules directly into cells and helps keep them active. It may solve a major problem in modern medicine: many therapies are trapped inside cells and lose their effect.
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NewsOne of cholera’s great enemies is found in the human gut
Cholera-causing bacteria are locked in an evolutionary arms race with a viral nemesis, according to a new genomic study. Researchers found that in the Ganges Delta, cholera bacteria rapidly gain and lose special armour that protects against attacks from the virus, known as bacteriophage ICP1.
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NewsViruses ‘eavesdrop’ on each other – but it can backfire
Viruses can “eavesdrop” on each other using chemical signals – but it can backfire for the eavesdropper, new research shows. Scientists studied chemical communication by phages, viruses that infect bacteria.
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NewsNew antibiotic alternative fights foodborne salmonella
Researchers have discovered a safe and highly effective natural virus that functions like a precision-guided missile, capable of eliminating harmful Salmonella on various foods and packaging materials, showing great potential as a novel guardian for food safety.
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NewsMapping the hidden gene highways of wastewater biofilms
A new study uncovers the hidden microbial connections within wastewater biofilms by combining Hi-C sequencing with multi-omics to directly map which phages and plasmids are associated with which microbial hosts.
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NewsHidden viral networks in soil microplastics may shape the future of sustainable agriculture
A new scientific review highlights the complex interactions between soil microbes and viruses that occur on the surface of microplastic particles. The study reveals that these microscopic relationships may influence soil health, ecosystem recovery, and the long term sustainability of agriculture.
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NewsScientists uncover mechanism used by three bacteria-killing viruses to target transporter
Biochemists have homed in on an underexplored small transporter called MurJ that is a vital part of the pathway bacteria use to build their chain-mail-like cell wall. Using advanced tools, the scientists have determined the common mechanism used by three different bacteria-killing viruses to block MurJ from doing its job.
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NewsNewly discovered virus linked to colorectal cancer
Researchers have discovered a previously undescribed virus in a common gut bacterium, Bacteroides fragilis. The virus appears more frequently in patients with colorectal cancer.
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NewsSilent enemies, smart weapons - switching off phage contamination using nanoparticles
Bacteriophages represent a serious threat to laboratories and industries that rely on bacterial cultures for production. Researchers have demonstrated an innovative solution that enables targeting the surface of bacteriophage through electrostatic interactions.
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NewsNext generation genetics technology developed to counter the rise of antibiotic resistance
The new Pro-Active Genetics (Pro-AG) tool called pPro-MobV is a second-generation technology that uses an approach similar to gene drives to disable drug resistance in populations of bacteria.
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FeaturesUnlocking the secrets of phages: DNA modification discoveries offer new weapons against antimicrobial resistance
Bacteria and their viral predator bacteriophages (phages) have coevolved for billions of years and are engaged in an endless arms race against each other. DNA modifications are among the most widespread defenses to block bacterial RM and CRISPR-Cas systems.
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FeaturesBuilding integrated biobanks to defeat AMR in chronic wounds
Antimicrobial resistance (AMR) has evolved into a complex global health issue which has outstripped the development of new antibiotics and therapeutic strategies. The World Health Organisation (WHO) estimates 1.27 million deaths were attributed to AMR infections in 2019. By 2050, 10 million deaths are predicted at a cost of $100 ...
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NewsUnder The Lens: Callum Cooper explores how bacteriophages could revolutionise medicine - and how we get to that point
In a compelling new video interview from Applied Microbiology International’s ‘Under the Lens’ series, Dr. Callum Cooper shares fascinating insights into one of medicine’s most promising frontiers: phage therapy.
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VideoThe Microbiologist: Under the Lens | Episode 2
In our second episode, Dr Callum Cooper joins Professor Emmanuel Adukwu to talk about all things bacteriophage, from alternatives to antibiotics, social impact, and regulation.
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NewsFive new phages discovered in university’s Botanical Gardens
Five new bacteriophages have recently been discovered in the ponds of Lund University’s Botanical Gardens. Phages thrive wherever bacteria are found, which often means ponds and watercourses that are rich in organic material.
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NewsNew collection of bacteria-eating viruses can tackle hospital superbug
An international team of researchers have comprehensively catalogued a new collection of bacteria-eating viruses called phages sourced, in part, from hospital wastewater. The phages have been shown to be effective against different strains of Klebsiella pneumoniae.
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NewsResearchers expand virus-based treatment options for antibiotic-resistant infections
Phages are extremely specific about which strains of a bacterial species they will attack. This has limited their effectiveness against the most antibiotic-resistant strains. To overcome this problem, the research team “trained” the phages by allowing them to evolve together with the bacteria in a controlled laboratory setting for 30 days.
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OpinionThe politics behind the global divide in bacteriophage therapy
The therapeutic potential of bacteriophages (or ‘phages’) has been widely dismissed for decades in the West, despite being regularly used to treat patients worldwide in the early and mid-20th century. In an age rife with disinformation, can the true potential of clinical phage technology be communicated to a public already uneasy about scientific intervention?