All Computational Biology articles
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Careers The First Microbiome Symposium of Puerto Rico and the Caribbean – new success for the COBRE Center for Microbiome Sciences
The inaugural Microbiome Symposium of Puerto Rico and the Caribbean marked a major milestone for microbiome science in the region and reinforced Puerto Rico’s growing leadership in interdisciplinary biomedical research, says chair Filipa Godoy-Vitorino of the University of Puerto Rico.
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NewsTiny ocean life helps scientists estimate whale prevalence off the California coast
Using an innovative alternative method, researchers examined microbial “ecological habitats” as highly accurate predictors of how many filter-feeding whales were occupying the California coast between 2014 and 2020 from San Diego to Morro Bay.
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NewsAI and supercomputer simulations reveal how a bacterial energy-converting enzyme pumps sodium ions
The Na+-NQR enzyme is vital for energy production in pathogenic bacteria, making it a highly promising target for new antibiotics. Researchers combined modified artificial intelligence techniques with extensive supercomputer simulations to visualize the hidden, dynamic movements of this enzyme during sodium transport.
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OpinionFertile ground: The rise of soil viral ecology
Soil viral ecology has been one of the most neglected areas of microbiology, but technological advances are opening up fertile new frontiers, says AMI Healthy Land Advisory Group member and CNRS researcher Christina Hazard.
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NewsComputational approach takes the guesswork out of drug development for Chagas disease
Researchers have established a computational protocol that could accelerate the development of more effective treatments for life-threatening parasitic infections such as Chagas disease, by enabling scientists to accurately identify reactions that can result in successful drug candidates without the need for trial and error.
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NewsScientists discover the antibacterial potential of ‘hero’ Korean skincare ingredient
Fans of Korean skincare may be familiar with ‘hero ingredient’ Madecassic acid for its skin-soothing properties, but researchers have revealed its greater potential for use in the battle against antibiotic resistance.
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NewsA smarter way to build vaccines: scientists harness AI to target emerging alphaviruses
Scientists have developed a new computational pipeline that could dramatically accelerate the development of vaccines against a group of mosquito-borne viruses known as alphavirus.
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NewsGetting a glimpse of viral dances in the dark in the Sargasso Sea
In a new study of viral abundance over a short time frame in the Sargasso Sea, researchers found that almost all viruses with cyclical changes in abundance were most active at night – a somewhat surprising find.
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NewsA new ecological model highlights how fluctuating environments push microbes to work together
A new study explores why interdependence can be a winning move for microbial communities. It demonstrated that a mathematical model of how bacteria produce and share resources accurately predicted the outcome of experiments with living E. coli strains.
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NewsEMBL pays tribute to Peer Bork (1963—2026)
The European Molecular Biology Laboratory has paid tribute to its Interim Director General, Professor Peer Bork who passed away in January. The institution reflects on the extraordinary impact Peer had on the world of science.
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NewsGrowing together, bacterium after bacterium
Social interaction among babies in their first year of life influences and enriches the diversity of their gut microbial strains, based on the findings of a study on microbiome transmission.
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NewsProfessor named EMBO Young Investigator for work on the infant microbiome
Prof. Moran Yassour has been selected as one of the 2025 EMBO Young Investigators. She receives this prestigious recognition for her innovative research on the developing infant microbiome and its impact on pediatric health.
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NewsAI can speed antibody design to thwart novel viruses: study
Artificial intelligence (AI) and “protein language” models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according to a multi-institutional study
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NewsHow algae help corals bounce back after bleaching
A $1.1 million project will uncover how reefs regain life-giving algae after suffering from heat stress. The three-year project will use advanced imaging and living experimental systems to learn what’s happening on a cellular level when algae return to bleached reefs.
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NewsStudy models how human behavior, lockdowns and restrictions shaped COVID’s spread
Researchers employed computer modeling and large datasets to better understand how COVID-19 was transmitted in one community in South Africa during the course of the worldwide pandemic.
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NewsHow viruses build perfectly symmetrical protective shells
Researchers used a new simulation framework to capture key biological factors like protein diffusion, genome flexibility, and shape-shifting behavior to model how viral proteins self-assemble into symmetric shells.
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NewsStudy evaluates airborne transmission risk of mpox compared to COVID-19 and smallpox
Scientists have found that the inhaled infectious dose of mpox is at least 100 times lower than that of SARS-CoV-2 and smallpox, making efficient respiratory aerosol transmission highly unlikely in its current form - but future viral evolution could alter this dynamic.
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NewsScientists ID natural products targeting SARS-CoV-2 - including caffeine
Researchers used computational methods to identify potential inhibitors of SARS-CoV-2 spike proteins, revealing promising natural compounds for guiding antiviral drug development, including caffeine.
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NewsSimulation model shows potential affordability of preventative HIV therapy for infants
A type of cost-effective HIV neutralizing antibodies was evaluated to prevent the viral infection in infants during breastfeeding in high HIV prevalance countries. This treatment option is comparatively cheaper and has high clinical impacts in high HIV burden settings to achieve global elimination.
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NewsMovie reveals DNA unzipping mechanism with implications for viral and cancer treatments
A detailed unwinding mechanism of the double-stranded DNA has been uncovered for the first time using cutting-edge technology, revealing how cells begin the crucial process of copying their genetic material.