All Disease Treatment & Prevention articles
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What exactly is Long COVID? It depends who you ask
New research finds that the definition of Long COVID varies so widely across published studies that the percentage of people identified as having the condition can differ dramatically, making it harder to treat patients and advance research.
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Investigating regional-specific gut microbial distribution: an uncharted territory in disease therapeutics
A new perspective highlights the critical role of region-specific gut microbial distribution across intestinal segments (e.g., duodenum, colon) in regulating host metabolism and immunity, challenging traditional fecal-centric approaches.
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New drug combo outperforms Tamiflu in fighting flu (and chocolate is the key)
Scientists have unveiled a new drug pairing - including a compound found in chocolate - that outperforms Tamiflu, the most widely used anti-influenza medication, against even the deadliest flu strains, including avian and swine flu.
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Gene therapy may block HIV transmission during breastfeeding, study shows
Delivering broadly neutralizing antibodies against HIV-1 to newborns via gene therapy provided them with multi-year protection from HIV/AIDS infection, according to an animal study.
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Study highlights the severity of acute necrotizing encephalopathy in kids with the flu
For a small subset of children, influenza can trigger a rare but serious complication called influenza-associated acute necrotizing encephalopathy (ANE). Now, findings of a multicenter study suggest that ANE is often fatal in these children — despite intensive treatment.
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Gut microbiome transplants show promise for boosting cancer immunotherapy
A comprehensive new review examines the effects of transferring healthy gut bacteria to cancer patients receiving immune checkpoint inhibitors (ICIs).
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Clinical trial finds safe, effective treatment for children with severe post-Covid syndrome
Researchers have discovered that a drug designed to treat Celiac disease supported a more rapid return to normal activities for patients following COVID. A small, randomized clinical trialfound the oral drug larazotide was both safe and effective in treating children with MIS-C.
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‘One and done’: A single shot at birth may shield children from HIV for years, study finds
A new study shows that delivering a single injection of gene therapy at birth may offer years-long protection against HIV, tapping into a critical window in early life that could reshape the fight against pediatric infections in high-risk regions.
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New AI tool accelerates mRNA-based treatments for viruses, cancers, genetic disorders
A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various cell types.
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Can a compound produced by deep-sea bacteria treat cancer?
Investigators purified a long-chain sugar molecule, or exopolysaccharide, from deep-sea bacteria and demonstrated that it triggers pyroptosis—an inflammatory form of programmed cell death—to inhibit tumor growth.
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Study identifies world-first treatments to prevent a life-threatening virus infection
A study found two HIV antivirals already on the market can suppress transmission of HTLV-1 in humanised mice and prevent disease. When used in combination with a compound that induces cell death, infected cells were killed – flagging a potential future curative strategy.
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Study reveals engineered bacterial vesicles to combat antimicrobial resistance
Researchers studying extracellular vesicles (EVs)-membrane-bound nanoparticles released by cells that transport biologically active molecules like proteins or nucleic acids have engineered EVs derived from lactic acid bacteria to carry pathogen-specific endolysins on their surface.
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The gut’s secret weapon: viruses that heal
A comprehensive new review reveals how gut viruses interact with gut bacteria and host immunity, highlighting their roles in conditions like inflammatory bowel disease, colorectal cancer, and C. difficile infection. The findings offer a compelling case for harnessing the virome in novel therapies to reshape gut ecology and restore health.
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When bacteria get hungry, they kill – and eat – their neighbors
Scientists have discovered a gruesome microbial survival strategy: when food is scarce, some bacteria kill and consume their neighbors. The researchers show that under nutrient-limited conditions, bacteria use a specialized weapon — the Type VI Secretion System (T6SS) — to attack, kill, and slowly absorb nutrients from other bacterial cells.
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People with COVID-like symptoms took up to nine months post-infection to regain mental well-being
New research finds that people with COVID-like symptoms returned to optimal physical well-being an average of three months after infection, but took up to nine months to return to top mental well-being.
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Twin study detects gut bacteria that play a role in development of multiple sclerosis
Researchers examined stool samples from 81 pairs of twins, and compared their composition between siblings. They identified 51 taxa—groups of microorganisms—that differed in abundance between twins with and without MS symptoms.
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New source of natural antibiotics hidden within our own proteins identified
A team of scientists has identified a new type of antimicrobial peptides (AMPs) found in human proteins that are capable of selectively eliminating multidrug-resistant bacteria, particularly of the gram-negative type, responsible for serious hospital acquired infections.
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Heatwaves greatly influence parasite burden; likely spread of disease
New research implies that heatwaves have a major influence on the spread of many diseases – and that many existing predictive models have overlooked this complexity. Differences in heatwaves can increase disease burden by up to 13 times in an animal model.
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Researchers engineer a herpes virus to turn on T cells for immunotherapy
Researchers have identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival - a promising tool in the fight against cancer.
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Gut fungi breakthrough: Novel fungus offers hope for metabolic diseases
Scientists have unveiled a gut fungus that could transform treatment for metabolic dysfunction-associated steatohepatitis (MASH). The fungus produces a compound that blocks CerS6, an enzyme responsible for producing ceramides, fat molecules linked to metabolic disorders.