All Disease Treatment & Prevention articles
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NewsScientists engineer antibody against flu with sticky staying power
Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The new molecule combines the specificity of a mature flu fighter with the broad binding capacity of a more general immune system defender. Source: NIAID Colorized transmission ...
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NewsMonoclonal antibody nirsevimab provides strong protection against severe RSV in infants
Nirsevimab, a monoclonal antibody, is highly effective in real-world conditions at preventing severe respiratory syncytial virus (RSV) infections in infants, suggests a meta-analysis.
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NewssiRNA plus nanovaccine yields stable functional cure for chronic hepatitis B
Researchers have developed an innovative therapy for chronic hepatitis B, synergistically combining their proprietary ferritin nanoparticle-preS1 (Ferritin-NP-preS1) therapeutic vaccine with a preclinically validated HBV-specific siRNA.
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NewsChiral phytovirucide targets viral Nia protein to inhibit proliferation
A new study focuses on the search for small molecules to target the Nia protein of Potato virus Y (PVY), one of the most economically destructive viruses affecting Solanaceous crops such as potatoes, peppers, and tomatoes.
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NewsGlobal study finds single-dose baloxavir reduces household influenza transmission
A landmark study reveals that a single oral dose of baloxavir marboxil (baloxavir) significantly reduces the transmission of influenza within households, marking a major advancement in influenza management.
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NewsTransatlantic collaboration to develop therapeutic for Crimean-Congo Hemorrhagic Fever
A new transatlantic collaboration will look to develop an affordable and accessible monoclonal antibody therapeutic for Crimean-Congo Hemorrhagic Fever Virus (CCHFV), which could treat and protect thousands of people globally.
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NewsThe very first structural images of a tuberculosis-fighting virus
Scientists have used advanced imaging techniques to provide a detailed look at how a tiny virus, known as a phage, invades Mycobacteria. The research could pave the way toward phage-based treatments for antibiotic-resistant mycobacteria.
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NewsA cocktail of drugs may work against a whole family of viruses
Enteroviruses cause everything from polio to meningitis. An effective treatment could help reduce the risk of this global health problem.
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NewsBacterium promotes liver regeneration by increasing β-hydroxybutyric acid (BHB) production and BHB-driven STAT3 signals
Parabacteroides distasonis promotes liver regeneration by increasing BHB production and BHB-driven STAT3 signals, providing an argument for using P. distasonis or BHB as a potential strategy for promoting hepatic regeneration after PHx or transplantation.
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NewsStudy of oral azvudine versus nirmatrelvir/ritonavir in elderly hospitalized COVID-19 patients
A study used five analytical methods to show that oral azvudine has a therapeutic effect in elderly COVID-19 patients aged over 60 years.
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NewsGut microbes could one day be deployed to tackle sleepless nights: review
Personalized pre/probiotic treatments could someday be used to support healthy sleep through stressful exam periods and menopause, a new review suggests.
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NewsNew research boosts future whooping cough vaccines
By blocking the pertussis toxin epitopes with new found antibodies, researchers improved the pertussis vaccines to provide stronger, long-lasting immunity for infected and high-risk infants.
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NewsNew COVID-19 drug shows greater promise against resistant viral strains
A new standalone oral drug candidate has proven to be effective against Paxlovid-resistant COVID-19 strain in animal models. It works with low doses and cause no drug interaction-induced side effects.
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NewsSome gut bacteria could make certain drugs less effective
Researchers discovered that gut bacteria can metabolize oral administered drugs that target G protein-coupled receptor (GPCR) and potentially other chemicals and food compounds, leading to impacts on the effectiveness of medication to patients.
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NewsmRNA-based COVID-19 vaccines train the ‘long-term memory’ of the innate immune system
A study showed that vaccination of multiple mRNA-based COVID-19 vaccines could induce persistent epigenetic changes in innate immune cells, leading to long-term immune responses for SARS-CoV-2 and other pathogens.
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NewsSimulation model shows potential affordability of preventative HIV therapy for infants
A type of cost-effective HIV neutralizing antibodies was evaluated to prevent the viral infection in infants during breastfeeding in high HIV prevalance countries. This treatment option is comparatively cheaper and has high clinical impacts in high HIV burden settings to achieve global elimination.
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NewsUpdated guidelines for pediatric Mycoplasma pneumoniae infection
In light of the rise in antibiotic resistance, new guidelines are released with detailed recommendations of diagnosis and treatment strategies for pediatric Mycoplasma pneumoniae pneumonia (MPP), along with the means to manage severe complications.
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NewsResearchers discover Achilles heel of Lyme disease pathogen
Researchers discovered and investigated an unique enzyme used in the pathway specific to Borrelia burgdorferi, the parasite that causes Lyme disease. The enzyme serves as the ideal genus-specific target for therapeutic intervention.
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NewsFDA-approved dialysis drug may help fight against antimicrobial resistance
In account of the imminent threat of antimicrobial resistance (AMR), a study revealed that the FDA-approved sevelamer, which is used to treat chronic kidney disease undergoing dialysis, is successful in the removal of other off-target antibiotics (vancomycin and daptomycin) from the gut.
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NewsResearch uncovers new strategy to reduce tissue damage from flesh-eating bacteria
A new study reveals a novel approach to mitigating tissue damage caused by Streptococcus pyogenes, the flesh-eating bacterium responsible for severe infections such as necrotizing fasciitis.