All Gut Microbiome articles
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Maternal antibodies in breast milk regulate early immune responses in mouse gut
In mice, maternal antibodies ingested in breast milk in the first week after birth help to regulate immune responses in the newborn gut, according to a new study.
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Scientists find a microbial molecule that restores liver and gut health
Researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure. The treatment may offer a new, non-toxic way to prevent and treat non-alcoholic fatty liver disease (NAFLD).
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Common food thickeners – long thought to pass right through us – are actually digested
It turns out cellulose-based thickening agents can be digested. Researchers have shown that our gut bacteria can feed on these large molecules – thought to not be possible – thanks to enzymes that normally help us break down dietary fibre.
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Reciprocal links likely between certain groups of gut bacteria and insomnia risk
Certain types of bacteria seem to boost or lower the risk of insomnia while the sleep disorder itself seems to alter the abundance of certain types of bacteria, suggests a Mendelian randomisation study.
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Fighting infections with the power of the microbiome
Scientists have discovered that bacteria of the species Klebsiella oxytoca can displace pathogenic bacteria from the gut and want to develop a living biotherapeutic based on this finding. The DZIF is now providing 2.2 million euros in funding for product development.
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Investigating regional-specific gut microbial distribution: an uncharted territory in disease therapeutics
A new perspective highlights the critical role of region-specific gut microbial distribution across intestinal segments (e.g., duodenum, colon) in regulating host metabolism and immunity, challenging traditional fecal-centric approaches.
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Research probes the gut microbiome and its metabolite short-chain fatty acids in postmenopausal osteoporosis
Postmenopausal osteoporosis (PMOP) is framed as a systemic bone disease driven by estrogen withdrawal, but a new review positions gut dysbiosis and its fermentation products—short-chain fatty acids (SCFAs)—as equally influential regulators of skeletal fate.
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Disarming a hidden killer: Predicting – and preventing – C. diff before it strikes
Researchers have developed a powerful, personalized modeling framework to predict whether Clostridioides difficile is likely to colonize an individual’s gut, and to test whether specific probiotic therapies might prevent and/or reverse that colonization.
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The microbiome of the indri, a critically endangered lemur, has been described
An international study has ascertained the composition of the intestinal microbiome of the indri, a critically endangered lemur in Madagascar. It has found up to 47 unknown species of bacteria, and revealed the indri’s microbiome is transmitted within their social group.
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Unlocking the hidden patterns of the gut microbiome with association rule mining
A new study introduces Association Rule Mining (ARM) as a powerful tool to uncover higher-order microbial interactions. The data mining technique allows researchers to identify frequent microbial patterns and their potential health implications.
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Brewed chicken protein made by precision fermentation tested in pet food
In a groundbreaking new project, scientists used precision fermentation to produce brewed chicken protein and evaluated it for use in pet food. Dogs that consumed the protein in their kibble during a six-month study had beneficial digestive effects, they found.
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Q&A: Why do symptoms linger in some people after an infection?
A new review highlights that long COVID and ME/CFS share many of the same biological problems such as inflammation in the brain, issues with how cells produce energy, and problems with the immune system.
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Helping me, inhibiting you: Analysis of interactions between intestinal microbiota
Researchers have analyzed the interactions between two bacteria that make up intestinal microbiota. While Faecalibacterium prausnitzii inhibits the growth of Fusobacterium varium, F. varium promotes the growth of F. prausnitzii.
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Microbiome breakthrough: Gut bacterium may hold key to future treatments for widespread chronic diseases
Scientists have identified a common specific gut bacterial strain that may open the door to a new class of therapeutics. This bacterium produces two proteins that influence the body’s hormonal balance and affect weight, bone density, and blood sugar levels.
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Gut microbiome transplants show promise for boosting cancer immunotherapy
A comprehensive new review examines the effects of transferring healthy gut bacteria to cancer patients receiving immune checkpoint inhibitors (ICIs).
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Gut microbes: How many molecules influence our body?
Researchers have precisely quantified how many molecules are produced by gut bacteria and arrive in the body every day, enabling them to calculate how many gut bacteria are used up and regenerated each day.
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How the common fungus Candida albicans colonizes the gut
Researchers have discovered unexpected factors that help the fungus Candida albicans settle and persist in the gut. The findings expand our knowledge of the fungus-gut interactions and offer potential solutions to reduce colonization.
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Trapping gut bacteria’s hidden fuel improves blood sugar and liver health, study shows
Scientists have discovered a surprising new way to improve blood sugar levels and reduce liver damage: by trapping a little-known fuel made by gut bacteria before they wreak havoc on the body. It could open the door to new therapies to treat metabolic diseases.
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New research uncovers gut microbe-derived metabolites as potential therapy for obesity-related metabolic disorders
New research reveals that certain gut microbial byproducts may hold promise as a novel therapy for obesity-associated metabolic complications by restoring critical hormone-producing cells in the intestine.
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New study finds distinct city-specific gut microbiota linked to diet
A new study shows that the human gut microbiota can pinpoint whether an adult lives in Wuhan or Shiyan, two cities 500 km apart in China’s Hubei Province, with 94 % accuracy. This microbial signature is strongly linked to each city’s characteristic diet.