All Gut Microbiome articles – Page 6
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News
Taking the sting out of ulcerative colitis
Researchers reveal that the intestinal flora works in combination with the mutated OTUD3 gene and STING signaling to aggravate ulcerative colitis.
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Controlled human gut colonization by an engineered microbial therapeutic
Engineered gut bacteria designed to treat kidney stones successfully colonized the gut microbiome and reduced oxalate levels in animal models and early clinical trials in humans, researchers report.
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Bacterial genomes hold clues for creating personalized probiotics
A new study demonstrates the ability to predict the nutritional adaptations of Bifidobacterium strains by analyzing the distribution of hundreds of metabolic genes in thousands of Bifidobacterium genomes.
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Disease-causing bacteria can deal with stink as long as they get a meal
Bacteria that cause intestinal infections typically avoid a stinky chemical — one that can kill them at high enough concentrations — inside human intestines, but they may actually swim toward it when a hearty meal is the reward.
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A gut microbiota metabolite linked to atherosclerosis could revolutionize diagnosis and treatment
A new study has identified a gut microbiota–derived metabolite, imidazole propionate (ImP), that appears in the blood during the early stages of active atherosclerosis, showing promise as a new diagnostic tool and opening the door to personalized treatment strategies.
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Antibiotic resistance predicts higher mortality risk in 17-year follow-up
A population-based study finds that in addition to antibiotic use, diet, sex, living environment, income level and certain gut bacteria are associated with a higher burden of resistance.
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Nighttime pistachio snacking may reshape gut microbiome in prediabetic adults
A new study has determined that nighttime pistachio consumption affects gut bacteria in adults with prediabetes. The potential therapeutic implications of the findings may prove significant for people who are working to improve their metabolic health.
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Early antibiotics alter immune function in infants- but a gut-derived molecule could help restore it
A new study has found that early-life exposure to antibiotics can impair an infant’s developing immune system, and that a naturally occurring metabolite may hold the key to reversing that damage.
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Acupuncture eases opioid therapy, rebalancing gut microbiota, study shows
Acupuncture significantly lowers methadone doses for people undergoing treatment for opioid use disorder, while restoring antiviral immune responses and rebalancing gut microbiota and metabolism, according to a new study.
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Long Reads
Tiny helpers: how our gut bacteria could protect us from forever chemicals
We are constantly exposed to things in our environment from the medicines we take and contaminants in the food we eat, to particles in the air we breathe. Figuring out which chemicals are harmful and how they affect us, is essential to make our surroundings safer.
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Gut morphology, not just diet or phylogeny, shapes mammalian gut microbiomes
Diet and evolutionary history have long been viewed as the main drivers of the mammalian gut microbiome. However, a new study offers the first systematic evidence that gut morphology significantly influences both the structure and function of gut microbial communities.
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Tokyo to host global summit showcasing leadership in microbiome medicine & fermentation science
Japan is reinforcing its position as a global powerhouse in microbiota research and fermentation science, as the country prepares to host the First Conjoint Meeting - International Society of Microbiota (ISM) - RIKEN, on Targeting Microbiota this October in Tokyo.
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Thyroid treatment may improve gut health in people with hypothyroidism
People with an underactive thyroid may have an increased risk of developing small intestinal bacterial overgrowth (SIBO), a risk that may be reduced with thyroid hormone treatment, according to a study.
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Chameleon plant polysccharide targets acute pneumonia with H1N1 and MRSA coinfection
A new study discusses how an anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut–lung axis and NLRP3 inflammasome activation.
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Gut microbes key to understanding how exercise boosts cancer immunity
A new study shows how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome. These benefits are driven by a specific compound called formate, which is produced by gut bacteria in exercised mice.
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Scientists investigate gut microbiota in elderly patients with acute hepatitis E infection
A new study of the impact of hepatitis E virus infection on the gut microbiota identifies a bacterial species as a potential biomarker for disease outcomes.
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Flightpath Biosciences licenses microbiome-sparing antibiotic developed at Illinois
Flightpath Biosciences, Inc., has licensed a class of antibiotics developed at the University of Illinois Urbana-Champaign. The original antibiotic agent, lolamicin, effectively treated bacterial infections in animal models of disease without wiping out beneficial gut microbes.
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Estrela brings microbial research to Texas A&M AgriLife Department of Nutrition
Sylvie Estrela, Ph.D., has joined the Texas A&M College of Agriculture and Life Sciences Department of Nutrition as an assistant professor. Estrela’s research focuses on microbial interactions, specifically, the way nutrients can impact bacterial communities.
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Multiresistant intestinal bacteria: Displacement through food competition
Researchers made use of food competition to figure out how potentially dangerous multi-resistant bacteria could be effectively removed from the gut before reaching the bloodstream and causing serious problems.
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The gut’s secret weapon: viruses that heal
A comprehensive new review reveals how gut viruses interact with gut bacteria and host immunity, highlighting their roles in conditions like inflammatory bowel disease, colorectal cancer, and C. difficile infection. The findings offer a compelling case for harnessing the virome in novel therapies to reshape gut ecology and restore health.