All Gut Microbiome articles – Page 5
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NewsCheese bacteria could offer health benefits
Scientists identified the microbial and biochemical profiles of three artisan cheeses made locally in Oxfordshire across their maturation process, and found that the bacteria responsible for a cheese’s character could also benefit the people who eat it.
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NewsNew study links gut bacteria to immunotherapy success in melanoma patients
Researchers have identified specific gut bacteria linked to better responses to cancer immunotherapy in patients with advanced melanoma. Patients who responded well to treatment were more likely to have a specific type of gut bacteria called Faecalibacterium.
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NewsMicrobiome insights may help predict immunotherapy benefit in kidney cancer
City of Hope researchers report that gut microbiome composition may influence how patients respond to immunotherapy combinations in metastatic renal cell carcinoma, pointing to a potential biomarker that could help guide treatment selection in the future. The microbiome is a rising focus at City of Hope, highlighted ...
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NewsModern medicine makes gut microbial diversity plummet
Even minimal exposure to modern medicine can rapidly change the human microbiome. Researchers reveal that the gut microbes of remote Amazonian Indigenous communities began shifting toward patterns more commonly seen in urban, industrialized populations after only a few medical visits.
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NewsLargest-ever Canadian clinical trial tests ‘poop pills’ to improve immunotherapy for lung cancer
For nearly half of people diagnosed with lung cancer, immunotherapy can slow the disease but not stop it. A clinical trial will pair immunotherapy with fecal microbiota transplantation (FMT) with the goal of safely increasing treatment effectiveness. If successful, it could provide new treatment options for people with lung cancer.
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NewsHost-based antifouling gold nanotube sensor for the selective detection of mechanically sensitive serotonin release in intestinal mucosa
A new study report a stretchable electrochemical sensing platform with high deformation insensitivity and strong antibiofouling capability. The platform enables in situ capture of dynamic small-molecule chemical signals in the gut, and revealed a new mechanism underlying enhanced intestinal mechanosensation under microbe-related stimulation.
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NewsA common disinfectant could affect how well your liver works
Common household cleaners and pharmaceutical products contain benzalkonium chlorides (BACs), a type of disinfectant. A new study shows that exposure to these compounds caused changes in gut microbiome composition in mice, as well as the genes that encode for liver enzymes that metabolize drugs.
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NewsStudy reveals “bet-hedging” strategy that helps gut bacteria survive and recover
Researchers have discovered that many gut bacteria use a flexible survival strategy to withstand disruptions such as antibiotics and diet changes. Microbes can switch between functional states, rather than relying solely on genetic mutations, to try to survive shifting conditions.
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NewsParaprobiotic counteracts damage to male fertility from BPA in plastic
BPA has been shown to impair sperm function, in part through increased generation of reactive oxygen species. Researchers investigated whether a paraprobiotic material derived from the lactic acid bacterium Enterococcus faecalis (known as FK‑23) protects against the sperm toxicity caused by BPA.
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NewsResearchers link human molecular, microbial diversity with geography, ethnicity
Researchers at the Stanford School of Medicine have found that ethnicity and geography may influence human molecular makeup — from metabolism and immunity to gut microbiota and biological aging. The findings, which published in Cell on May 14, illuminate the complex interplay between genetics and the environment, ...
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NewsProbiotic Lactobacillus rhamnosus CMU-pb-7 shows promise in alleviating diabetic nephropathy via antioxidative pathway
Rats with diabetic nephropathy treated with the probiotic strain Lactobacillus rhamnosus CMU-pb-7 showed marked improvements in general condition and serum biochemical profiles, including significant reductions in cholesterol, triglycerides, blood urea nitrogen, and serum creatinine.
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NewsBody weight affects your gut microbiota
A new study demonstrates that there is a correlation between gut microbiota and body weight. Researchers also observed that having a high BMI is detrimental to gut microbiota.
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NewsFrom Helicobacter pylori to the AMR crisis: our interview with JAM Microbiology in Health and Disease Lead Editor Liang Wang
We get to know Professor Liang Wang, who has just been appointed as new Lead Editor in Microbiology in Health and Disease at the Journal of Applied Microbiology.
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NewsFrom ocean to gut: The bacteria that shape both human health and marine carbon cycling
A group of researchers has discovered that Akkermansia bacteria are not unique to our guts, but can also be found in the ocean. In both habitats they use similar skills to ensure their survival and success. They seem to carry an old and widespread survival toolkit.
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NewsIntestinal stem cells can fight back against salmonella scientists discover
Researchers have shown that intestinal stem cells can directly sense intracellular Salmonella enterica bacteria and activate an inflammasome-dependent response. Following infection, the stem cells differentiate into antimicrobial Paneth cells, which secrete molecules that help limit bacterial persistence in the intestinal crypt.
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NewsGut microbiota plays a role in metabolic health after bariatric surgery
Changes in gut microbiota after bariatric surgery are strongly linked to altered metabolic health and sustained improvement in type 2 diabetes. A study shows changes in gut bacterial composition and function are associated with metabolic improvements, including insulin release and blood sugar control.
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NewsMouse study suggests high-fat diets during pregnancy worsen severe GI illness in preterm babies
A new mouse study suggests a link between a high-fat prenatal diet and induction of potentially deadly symptoms of necrotizing enterocolitis (NEC) in premature babies.
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NewsScientists discover how gut bacteria toxin invades colon cells to trigger cancer
A common gut bacterium, Bacteroides fragilis, drives colon tumor formation, potentially leading to colorectal cancer, by secreting a toxin that damages the lining of the colon. Researchers have now shown that the B. fragilis toxin BFT must first bind host receptor claudin-4 before it can cause damage.
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NewsThe Nexus of Food Systems, Ecosystems and Human Health: Sign up for our fascinating free webinar!
What if health is not produced by humans alone, but co-created with the ecosystems, organisms, and food systems we depend on? A fascinating free webinar will explore how microbes connect people to food systems and the ecosystems that undergird food production.
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NewsHead impacts associated with altered gut microbiome in football players
Non-concussive head impacts—hits to the head that don’t cause clinically detectable symptoms—are correlated with subsequent changes to the gut microbiome in a small sample of US collegiate football players, according to a new study.