All Gut Microbiome articles – Page 4
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Are probiotics worth the cost to prevent infection after a colon removal surgery?
A study found that taking an 8-strain probiotic daily may reduce the risk of pouchitis, a common inflammatory condition that occurs after colon removal surgery for ulcerative colitis, but the treatment may not be worth the cost depending on a patient’s likelihood of flare-ups.
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New papers reveal how gut-brain interactions shape eating behaviors
Researchers found that stress from life circumstances can disrupt the brain-gut-microbiome balance. This disruption may alter mood, decision-making, and hunger signals — increasing the likelihood of craving and consuming high-calorie foods.
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Researchers uncover relationship between gut fungi, human genetic variation and disease risk
A study uncovers evidence of the first ternary relationships between human genetic variation, variation in gut mycobiome, and risk of developing chronic disease.
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Study finds significant health benefits from gut microbes transfer
A cohort of overweight teens who received fecal transfer eight years ago were found to have reduced risk for a series of metabolic changes which can lead to heart disease, stroke and diabetes, compared with the participants who received the placebo.
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GI tumor microbes may predict prognosis and inform treatment
Intratumor microbes can play a role in disease progression and response to treatment. Researchers have identified core tumor microbiota associated with disease progression and risk, developing a microbiota-based risk score that can predict response to therapy.
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Researchers uncover sensory abilities of bacteria in the gut
An international team has shown that commensal bacteria can perceive and respond to diverse chemical stimuli in their environment. They focused on Clostridia, motile bacteria that play an important role in gut health.
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Alcohol opens the floodgates for bad bacteria
Scientists have found that chronic alcohol use impairs the production of a key cellular signaling protein that helps keep gut bacteria within the gut. Without this guardrail in place, bacteria from the gut can more easily migrate to the liver, exacerbating liver damage caused by alcohol.
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Mouth to gut bacteria migration explains why smoking is good for inflamed bowels
Researchers have discovered why smoking tobacco helps people suffering from ulcerative colitis. The study shows that smoking produces metabolites that encourage bacteria from the mouth to grow in the large intestines where they trigger an immune response.
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Yogurt and hot spring bathing show a promising combination for gut health
Researchers have demonstrated that yogurt intake increases the diversity of gut microbiota and alters its composition. Furthermore, bathing in chloride hot springs after yogurt intake was found to improve defecation status more than yogurt alone.
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Gut bacteria can reveal colorectal cancer
Researchers identified all human gut bacteria to a level of detail that uncovers the physiological importance of the different microbial subgroups. This inventory was then used to detect the presence of colorectal cancer according to the bacteria present in simple stool samples.
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Colibactin-producing E. coli linked to higher colorectal cancer risk in FAP patients
Researchers have found that patients carrying colibactin-producing Escherichia coli in their colon polyps were more than three times as likely to have a history of colorectal cancer compared to those without the bacterium.
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Kidney fibrosis linked to molecule made by gut bacteria
A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis — a serious complication of diabetes and a leading cause of kidney failure.
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Maternal antibodies in breast milk regulate early immune responses in mouse gut
In mice, maternal antibodies ingested in breast milk in the first week after birth help to regulate immune responses in the newborn gut, according to a new study.
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Scientists find a microbial molecule that restores liver and gut health
Researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure. The treatment may offer a new, non-toxic way to prevent and treat non-alcoholic fatty liver disease (NAFLD).
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Common food thickeners – long thought to pass right through us – are actually digested
It turns out cellulose-based thickening agents can be digested. Researchers have shown that our gut bacteria can feed on these large molecules – thought to not be possible – thanks to enzymes that normally help us break down dietary fibre.
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Reciprocal links likely between certain groups of gut bacteria and insomnia risk
Certain types of bacteria seem to boost or lower the risk of insomnia while the sleep disorder itself seems to alter the abundance of certain types of bacteria, suggests a Mendelian randomisation study.
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Fighting infections with the power of the microbiome
Scientists have discovered that bacteria of the species Klebsiella oxytoca can displace pathogenic bacteria from the gut and want to develop a living biotherapeutic based on this finding. The DZIF is now providing 2.2 million euros in funding for product development.
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Investigating regional-specific gut microbial distribution: an uncharted territory in disease therapeutics
A new perspective highlights the critical role of region-specific gut microbial distribution across intestinal segments (e.g., duodenum, colon) in regulating host metabolism and immunity, challenging traditional fecal-centric approaches.
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Research probes the gut microbiome and its metabolite short-chain fatty acids in postmenopausal osteoporosis
Postmenopausal osteoporosis (PMOP) is framed as a systemic bone disease driven by estrogen withdrawal, but a new review positions gut dysbiosis and its fermentation products—short-chain fatty acids (SCFAs)—as equally influential regulators of skeletal fate.
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Disarming a hidden killer: Predicting – and preventing – C. diff before it strikes
Researchers have developed a powerful, personalized modeling framework to predict whether Clostridioides difficile is likely to colonize an individual’s gut, and to test whether specific probiotic therapies might prevent and/or reverse that colonization.