All Gut Microbiome articles – Page 3
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Thyroid treatment may improve gut health in people with hypothyroidism
People with an underactive thyroid may have an increased risk of developing small intestinal bacterial overgrowth (SIBO), a risk that may be reduced with thyroid hormone treatment, according to a study.
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Chameleon plant polysccharide targets acute pneumonia with H1N1 and MRSA coinfection
A new study discusses how an anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut–lung axis and NLRP3 inflammasome activation.
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Gut microbes key to understanding how exercise boosts cancer immunity
A new study shows how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome. These benefits are driven by a specific compound called formate, which is produced by gut bacteria in exercised mice.
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Scientists investigate gut microbiota in elderly patients with acute hepatitis E infection
A new study of the impact of hepatitis E virus infection on the gut microbiota identifies a bacterial species as a potential biomarker for disease outcomes.
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Flightpath Biosciences licenses microbiome-sparing antibiotic developed at Illinois
Flightpath Biosciences, Inc., has licensed a class of antibiotics developed at the University of Illinois Urbana-Champaign. The original antibiotic agent, lolamicin, effectively treated bacterial infections in animal models of disease without wiping out beneficial gut microbes.
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Estrela brings microbial research to Texas A&M AgriLife Department of Nutrition
Sylvie Estrela, Ph.D., has joined the Texas A&M College of Agriculture and Life Sciences Department of Nutrition as an assistant professor. Estrela’s research focuses on microbial interactions, specifically, the way nutrients can impact bacterial communities.
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Multiresistant intestinal bacteria: Displacement through food competition
Researchers made use of food competition to figure out how potentially dangerous multi-resistant bacteria could be effectively removed from the gut before reaching the bloodstream and causing serious problems.
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The gut’s secret weapon: viruses that heal
A comprehensive new review reveals how gut viruses interact with gut bacteria and host immunity, highlighting their roles in conditions like inflammatory bowel disease, colorectal cancer, and C. difficile infection. The findings offer a compelling case for harnessing the virome in novel therapies to reshape gut ecology and restore health.
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New immunotherapy strategy targets difficult-to-treat brain tumors with gut microbiota
Researchers have demonstrated a new therapeutic strategy that can enhance the efficacy of immunotherapy for brain tumors by utilizing gut microbes and their metabolites. This also opens up possibilities for developing microbiome-based immunotherapy supplements in the future.
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Prebiotics might be a factor in preventing or treating issues caused by low brain GABA
Dietary prebiotics may induce an increase in brain GABA levels through the regulation of gut microbiota, which can be a major point for reducing or even treating these occurrences of certain neurological diseases in individuals.
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Study links influenza A viral infection to microbiome, brain gene expression changes
Infection with influenza A is found to be associated with disruptions in newborn piglets’ nasal and gut microbiomes and with potentially detrimental changes in gene activity in the hippocampus, a brain structure that plays a central role in learning and memory.
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Tracking microbial rhythms reveals new target for treating metabolic diseases
Researchers harness the benefits of time-restricted feeding on the gut microbiome — with the ultimate goal of developing new therapies for obesity, diabetes and related diseases.
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Gut microbiome composition and food insecurity linked to risk of cognitive impairment in adults
A new study has found a compelling link between the composition of the gut microbiome and the risk of cognitive impairment (RCI) in adults, underscoring the complex role that both biology and social determinants—such as food insecurity—play in brain health.
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First systematic review finds gut-brain axis impacts treatment outcomes in bipolar patients
A new review suggests that there is a significant connection between the gut and brain in patients treated for bipolar disorder and that this affects the ways in which a patient responds to treatment.
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Understanding inflammatory bowel disease: An integrative framework of microbiome, metabolome, and immunological biomarkers
A new review underscores the interconnected roles of microbial, metabolic, and immune biomarkers in IBD. While current biomarkers lack universal specificity, integrative approaches and AI-driven analyses offer transformative potential for precision medicine in IBD care.
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Researchers establish link between form and function of gut bacterium
New insights into the functional differences between the various morphotypes of Bacteroides thetaiotaomicron could open up new possibilities for medicine. A better understanding of their diversity could lay the foundation for novel microbiome-based therapies.
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International comparison reveals gender differences in antimicrobial resistance
A recent study analysed the DNA map of more than 14,000 gut metagenomes in a global dataset and found differences in antibiotic resistance between genders. In high-income countries, women had more antibiotic resistance genes than men.
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Immune tolerance to gut microbes is initiated by a key bacterial sensor
A study has found that the body’s immune “tolerance” to gut microbes depends on an ancient bacterial-sensing protein called STING—normally considered a trigger for inflammation.
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Gut microbes may help in recognizing and treating pancreatic cancer
A new international cooperation study indicates that in the future pancreatic cancer may be detected at an early stage with the help of gut microbes. Gut microbes may also offer solutions for therapy development.
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Fusobacterium nucleatum in colorectal cancer: Ally mechanism and targeted therapy strategies
A recent review systematically outlines the pathogenic mechanisms of Fusobacterium nucleatum in colorectal cancer and summarizes both current and emerging strategies for its therapeutic targeting.