All Gut Microbiome articles – Page 2
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News
New insights into how pathogens build protein machinery for survival in the gut
New research reveals how pathogenic bacteria construct tiny protein-based compartments, known as Eut microcompartments, which enable them to digest ethanolamine - a nutrient commonly found in the gut.
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News
Summer studentship: Eoin probes medicine-microbiome interactions using in vitro gut model
Eoin McKernan reports back on his AMI-sponsored summer studentship which focused on the relationships between the gut microbiome and the metabolism of variable response drugs.
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Opinion
Key lessons from the saMBA studies on human gut microbiome diversity
A recent study published in Nature Communications introduced the South American MicroBiome Archive (saMBA). The study offers several critical insights that deserve careful consideration.
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News
How the gut microbiome helps Japanese macaques eat with the seasons
A study shows that both the composition and fermentative ability of the Japanese macaque gut microbiome shift flexibly across seasons, while the latter in particular increased during the harsh winter when macaques relied on leaves.
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News
Vast gut microbiome diversity and antibiotic resistome across 14 mammal species on the Tibetan Plateau
A new study provides the most comprehensive genomic catalogue to date of mammalian gut microbiomes from the Tibetan Plateau.
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News
Christensenella tenuis inhibits gut-derived endotoxins to alleviate metabolic disorders
The gut probiotic Christensenella tenuis significantly alleviates endotoxemia and metabolic disorders by modulating gut bile acids (BAs) metabolism and suppressing lipopolysaccharide (LPS) translocation across the gut barrier, a new study finds.
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News
Sugary drinks influence the psyche via the intestine
A new study provides strong evidence that sugary drinks affect not only metabolic but also mental health – especially in women. This effect is probably mediated by the sensitive microbiome of the intestine.
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News
Milk matters: How donor human milk storage affects preemie gut health
A study reveals that shorter storage durations of donor human milk are linked to reduced gastrointestinal complicatoins in premature infants, including necrotizing enterocolitis. These findings suggest that minimizing milk storage time may help to preserve protective properties crucial for preterm gut health.
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News
Key to the riddle of sleep may be linked to bacteria
New research suggests a new paradigm in understanding sleep, demonstrating that a substance in the mesh-like walls of bacteria, known as peptidoglycan, is naturally present in the brains of mice and closely aligned with the sleep cycle.
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News
Fatty acids feed cancer-promoting bacteria: How chronic cellular stress alters the gut microbiome
Researchers have identified a cellular mechanism that alters the gut microbiome in a way that promotes cancer. An analysis of patient data shows that the findings also apply to humans.
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News
Gut bacteria linked to how our genes switch on and off, research finds
The trillions of microbes that live in the human gut may play a bigger role in health than previously thought, according to a review highlighting how the gut microbiome can affect epigenetics, the process that turns genes on or off without changing the DNA itself.
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News
Gut punch: $2 million to decode bacteria’s role in fighting disease
A $2 million grant to UC Riverside will explore how gut bacteria shape human health. The NIH award will support Ansel Hsiao’s lab in its quest to answer questions about how gut microbes communicate with each other and with their human hosts to influence health.
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News
Engineered gut bacteria improves survival outcomes in colorectal cancer tumors
A genetically modified Salmonella typhimurium strain can colonise tumours and release a therapeutic protein, LIGHT, to induce the formation of mature tertiary lymphoid structures (mTLSs) in laboratory models.
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News
Study links chronic sickle cell pain to gut microbial imbalance
Researchers have found a clear connection between chronic sickle cell disease pain and the bacteria present in the gastrointestinal tract. The team alleviated chronic pain by transplanting bacteria from the feces of healthy mice into the digestive tract of sickle cell animals.
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News
Oral bacteria linked to Parkinson’s via the gut-brain axis
Researchers have identified the mechanism by which metabolites produced by oral bacteria in the gut may trigger the development of Parkinson’s disease.
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News
Yeast in gut microbiome can worsen salmonella infection
Researchers have discovered that a yeast commonly found in our gut can make infection with salmonella worse. Salmonella binds to Candida albicans and triggers a chain reaction that allows the bacteria to better invade cells lining the intestines.
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News
Molecular roadmap links stomach infection to cancer risk
A new study has identified protein signatures that trace the trajectory from Helicobacter pylori infection to the progression of gastric lesions and eventual cancer. Researchers pinpointed 28 proteins that change consistently during this process.
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News
Beer and wine: the latest microbe-related discoveries
To produce haziness, researchers added yeast extracts to two brands of clear lager - and reported what happened. Another team carried out lab tests investigating how sulfites added to wine and an ethanol-containing liquid affect gut bacteria.
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News
Food additives in pregnancy: effects on offspring microbiota increase susceptibility to inflammatory diseases
A study conducted in mice reveals that maternal consumption of dietary emulsifiers can have a negative impact on the gut microbiota of their offspring and may increase their risk of developing chronic inflammatory gut disorders and obesity in adulthood.
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News
Research breakthrough offers hope for new colorectal cancer treatments
Researchers have identified the key mechanism by which Fusobacterium nucleatum binds to the human cell receptors CEACAM1 and CEACAM5, which are frequently overexpressed on many types of cancer cells.