All Structural Biology articles
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New study reveals how Sudan virus binds to human cells
The interaction between human NPC1 receptor and Sudan virus, closely related to Ebola virus, has been structurally characterised, and gives insight to the pathogenesis of other related filoviruses.
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Study uncovers how dengue virus hijacks human plasmin for infection
Scientists characterized and revealed the correct structural bindings between dengue virus and human plasmin from mosquito blood meal to allow better understanding in dengue virus pathogenesis.
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Structural insights reveal potential drug target in trypanosome parasites
A research group has recently characterised the structural differences between human and trypanosomal nuclear cap-binding complex, a key player in cellular RNA metabolism, for future drug development of trypanosomal diseases.
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Scientists uncover structure of critical component in deadly Nipah virus
Through the structural and functional study of the deadly Nipah virus, a research team has identified a crucial viral component, viral polymerase complex, within its multiplication machinery, with which a part of the enzyme could potentially serve as a therapeutic target.
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What enables herpes simplex virus to become impervious to drugs?
Research pinpoints the key to the cold sore virus’s ability to evade treatment, offering broader clues on antiviral drug resistance.
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3D shapes of viral proteins point to previously unknown roles
Scientists uncover an ancient immune-evading strategy shared by animal viruses and viruses that infect bacteria; findings may help in the development of new antiviral therapies.
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Gram-negative bacteria build outer membrane into body armour-like structure
A new study has shed light on how Gram-negative bacteria like E. coli construct their outer membrane to resemble body armour, which has far-reaching implications for the development of antibiotics.
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Deep learning tool identifies bacteria in micrographs
Deep learning software Omnipose is helping to solve the challenge of identifying varied and miniscule bacteria in microscopy images and can now identify several other types of tiny objects in micrographs.