All USA & Canada articles – Page 26
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NewsPopular GLP-1 drug may slow down biological aging in people with HIV
A new study provides the first randomized, placebo-controlled clinical evidence that semaglutide, a widely used GLP-1 drug, slows down the accumulation of biological aging markers in the DNA of adults with HIV.
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NewsStudy identifies serious infection risks linked to targeted cancer therapies
A major real-world study has found serious blood-related side effects associated with antibody-drug conjugates, an increasingly important class of targeted cancer therapies. Some ADCs were associated with substantial rates of severe neutropenia – dangerously low levels of infection-fighting white blood cells – and related complications.
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NewsPhase 1 clinical trial set to begin on first leishmaniasis vaccine
A phase 1 clinical trial testing the safety of a leishmaniasis vaccine is set to begin in the coming months. The live vaccine, found to be safe in animals, is expected to be tested in humans later this year.
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NewsResearchers evaluate NASA medication storage protocols
Researchers evaluated NASA’s medication handling practices, which currently call for removing medications from their original packaging and storing them in resealable plastic bags. The investigation found that active pharmaceutical ingredients degrade at a higher rate when stored in bags.
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NewsNew study uncovers why the Arctic’s rivers are rusting
Scientists have identified the two biggest reasons that once-pristine rivers across the Arctic are growing cloudy with toxic orange iron particles that smother insects and suffocate fish. As the climate warms, a layer of Arctic soil that had been frozen for millennia has begun to thaw.
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News‘Accidental’ discovery lays foundation for novel flu treatment strategies
Scientists investigating how influenza viruses replicate within cells “accidentally” discovered that different flu viruses use distinct strategies to infiltrate cells in the first place. They also found that it is possible to target specific molecules to prevent the viruses from entering new cells, thereby stopping their replication.
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NewsEngineered gut bacteria therapy emerges as scalable potential alternative to fecal microbiota transplants following clinical trial
Researchers have developed a new manufacturing platform for producing targeted mixtures of beneficial gut bacteria, an approach that could help expand access to microbiome-based therapies for patients with recurrent Clostridioides difficile (C. difficile) infection.
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NewsReal-time brain monitor detects infections earlier
A research team has created a new monitoring system to save lives and significantly reduce health-care costs in brain-injury cases through the early detection of infections in intensive care units. NeuroSense connects to drainage lines to detect biomarkers of infection.
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NewsScientists map the ocean’s invisible workforce
A new study identifies a small set of “metabolic niches” — or functional roles — that help explain how marine microbes grow, compete for resources and recycle carbon around the globe. The microbes are incredibly diverse, but their behavior can be grouped into a manageable number of strategies.
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NewsWhat is the link between HIV and chronic pain?
A mouse study reveals a mechanism linking HIV to chronic pain. Targeting each of the molecular players in this mechanism alleviates pain and may hold treatment promise for HIV-associated pain, though more work is needed.
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NewsOne simple trick makes zebrafish a better model for microbiome research
A new advance in animal husbandry involving a popular aquarium fish should speed the pace of discovery in laboratory studies of host-microbe interactions, researchers report.
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NewsBehind the diagnosis: How laboratory testing guided a complex histoplasmosis case
A diagnosis of histoplasmosis forced a teenager with juvenile arthritis onto an uncertain path, one defined by months of treatment, recovery, and a long-term course of antifungal therapy expected to last up to three years. Histoplasma capsulatum, a dimorphic fungus that causes histoplasmosis, found its way into her lungs.
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NewsPrecigen presents new long-term durability data for PAPZIMEOS, recently granted seven-year market exclusivity
Precigen, Inc. has announced updated long-term follow-up data from the pivotal study of PAPZIMEOS™ (zopapogene imadenovec-drba) for the treatment of adults with recurrent respiratory papillomatosis (RRP).
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NewsNew analysis confirms benefits of childhood flu vaccines
Pediatric flu vaccines significantly reduce the number of childhood cases of influenza, new research confirms. The findings show that for every 100 children vaccinated, between nine and 14 fewer children catch the flu.
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NewsNew study suggests fish gut microbe helps regulate ocean health
New research reveals a potential link between the gut microbes of a fish and global ocean processes, offering new insight into how marine ecosystems help regulate ocean chemistry and the marine carbon cycle.
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NewsResearch shows plants such as canola, tomatoes and rice reduce iron uptake when stressed by drought
New research has found that plants, ranging from canola to rice to tomatoes, actively shut down their own ability to take up iron when they experience drought. The study questions whether plants send out a ‘cry for help’ when they are stressed by drought to recruit beneficial soil microbes in their roots.
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NewsResearchers discover tick protein that may block disease transmission
Researchers have found that ticks produce an exosomal glycine-rich protein that plays a vital role in helping ticks feed and transmit viruses. When they used genetic tools to silence the gene responsible for this protein, ticks lacking the protein struggled to feed effectively and showed reduced body weight after feeding.
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NewsProtective soybean seed fungicide treatment may not increase profitability
Researchers analyzed how seed treatments affect yield and profitability in soybean farms in the Midwest and found that yield gains were modest and often did not offset the added cost of the treatment. Additionally, financial benefit was likely only when seed treatment costs were low and soybean prices were high.
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NewsHealth researchers call for support to develop pandemic prevention
The Vanderbilt Center for Antibody Therapeutics has received large-scale government grants and contracts to fund the discovery of human antiviral antibodies. The problem is the next step — finding corporate partners to develop the antibodies through human testing.
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NewsSoil scientist awarded $1.6 million NSF grant to study ‘living skin’ of arid ecosystems
A soil scientist has received a $1.6 million, five-year grant from the U.S. National Science Foundation (NSF) to fund her team’s study of how increasing temperature fluctuations impact the biocrust microbiome — the complex, thin-layer microbe community that stabilizes soil, fixes nitrogen and drives nutrient cycling in drylands.