All USA & Canada articles – Page 31
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Research suggests common viral infection worsens deadly condition among premature babies
Researchers say they found that infection with a common virus that can be transmitted from mother to fetus before birth significantly worsens an often-fatal complication of premature birth called necrotizing enterocolitis (NEC) in experiments with mice.
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Scientists invent new drug candidates to treat antibiotic-resistant bacteria
Researchers designed a new family of antibiotics that’s a variation of an existing drug called vancomycin, which is used as a last resort for extremely ill patients. The new version of vancomycin targets, bonds to and renders inactive two different parts of a molecule on the surfaces of pathogenic bacteria.
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Stealth virus: Zika virus builds tunnels to covertly infect cells of the placenta
Researchers have discovered that Zika virus in the placenta builds underground tunnels, a series of tiny tubes called tunneling nanotubes, that facilitate the transfer of viral particles to neighboring uninfected cells.
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Promising antibody may prove useful against deadly Ebola virus outbreaks
New research reveals the workings of a human antibody called mAb 3A6, which may prove to be an important component for Ebola virus therapeutics.
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Promising new class of antimalarial drugs discovered
A new study identifies an inhibitor of gene regulation that specifically kills the malaria pathogen. The chromatin remodeler PfSnf2L is a key regulator of genes that play an important role in various stages of the pathogen’s development.
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Study calls for better measures of poverty to strengthen tuberculosis research
A new review examines existing methods for assessing socioeconomic status in TB studies and highlights their shortcomings. The authors call for better, standardized poverty metrics to improve research and policy.
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Chlorine plus UV light degrades toxins caused by harmful algae blooms
Scientists examining the combination of ultraviolet light and chlorine to detoxify water laden with toxins from cyanobacteria have demonstrated that this combination significantly enhanced the degradation of toxins compared to chlorine alone.
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Paxlovid’s impact on hospitalization and death in COVID-vaccinated older adults far weaker than previously thought
A new study overturns the assumption that Paxlovid’s effectiveness in reducing COVID-19 hospitalizations and deaths in unvaccinated adults also applies to vaccinated adults.
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Machine learning framework can decipher immune system’s record of past infections
A novel machine learning framework can decipher an individual’s immune system’s record of past infections and diseases, providing a powerful tool with the potential for diagnosing autoimmune disorders, viral infections, and vaccine responses with precision.
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Neonatal HSV infections may lead to long-term cognitive impairment
A study has demonstrated that maternal vaccination against herpes simplex virus (HSV) could ameliorate neurological impairment from infected offspring in mice, providing insights for human clinical trials and other neurodegenerative disorders.
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Digging into a decades-old hepatitis B mystery suggests a new potential treatment
In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish infection of liver cells, researchers have identified a vulnerability that opens the door to new treatments.
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Coffee grounds and Reishi mushroom spores can be 3D printed into a compostable alternative to plastics
Researchers have developed a new system for turning coffee grounds into a paste, which is inoculated with Reishi mushroom spores to form a mycelial skin. The skin turns the coffee grounds into a resilient, fully compostable 3D printable alternative to plastics.
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1 in 5 older adults get infections after heart surgery, and women have a 60% higher risk
One in five older adults gets an infection up to six months after heart surgery, with women far more likely to develop one, according to two studies which examined thousands of cases of coronary artery bypass grafting.
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Transforming HIV diagnosis: a low-cost, point-of-care detection solution
A team of researchers has developed an innovative handheld device for human immunodeficiency virus (HIV) detection that combines paper-based sample preparation with real-time isothermal amplification.
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Fungal compound could help protect against influenza
A preclinical trial uncovers how beta-glucan, a compound found in all fungal cell wall, can ‘reprogram’ immune cells to prevent lung inflammation from influenza and lower the risk of death by the host immune responses.
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Scientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
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Monitoring approach could help snuff out Legionella outbreaks
Routine, relatively low-cost monitoring of several factors influencing water safety could ward off Legionnaires’ disease outbreaks in hospitals, nursing homes and other health care settings, a new study suggests.
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Professor awarded NSF grant to advance research on silica-scaled chrysophytes
A new National Science Foundation (NSF) grant will support a major effort to synthesize decades of research on protists. The project will integrate findings from Professor Peter Siver’s lifelong study of silica-scaled chrysophytes, a group of protists found in freshwater environments.
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Using population-level characteristics for the surveillance of antimicrobial-resistant gonorrhea
As the antimicrobial-resistant (AMR) gonorrhea poses a major threat to public health, there is an urgent need for expanding the surveillance of its prevalance to control the spread of the pathogen, through monitoring its association with the population density and HIV prevalence in cities.
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The hidden battle in your gut: How one bacterium outsmarts its rivals
Scientists have undertaken a deep dive into the inner workings of the ‘microbial arms race’ in your gut, revealing an elegant strategy that gut microbes use to stay a step ahead of their neighbors.