All Immunology articles – Page 19
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NewsNanoparticles that self-assemble at room temperature could transform vaccine delivery
Researchers have engineered polymer-based nanoparticles that form with a simple temperature shift—no harsh chemicals, no specialized equipment, and no processing needed. They can self-assemble at room temperature and deliver RNA to living cells.
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NewsWhy killer cells can lapse into ‘exhausted’ CD8+ T cells that no longer can stem disease
In a detailed study of exhausted T cell subsets researchers show that a transcriptional repressor called Gfi1 is a key regulator of the subset formation of exhausted CD8+ T cells and may offer a key to reducing exhaustion.
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NewsAUN bacteria herald an immune-independent breakthrough
A joint research team has developed a groundbreaking immune-independent bacterial cancer therapy using a novel microbial consortium called AUN (阿吽), composed of two naturally occurring bacteria: a tumor-resident microbe and photosynthetic bacterium.
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NewsSmart wound monitor poised to improve chronic infection care
Researchers have developed a wearable wound monitoring device with integrated sensors that could reduce infection risks by minimising the need for frequent physical contact.
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NewsScientists discover how leukemia virus stays hidden in the body
A research team has discovered how the human T-cell leukemia virus type 1 (HTLV-1) silently persists in the body. Their findings identify a previously unknown genetic “silencer” element that keeps the virus in a dormant, undetectable state.
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NewsQ&A: Why do symptoms linger in some people after an infection?
A new review highlights that long COVID and ME/CFS share many of the same biological problems such as inflammation in the brain, issues with how cells produce energy, and problems with the immune system.
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NewsSkin test reagent proves effective and safe for TB diagnosis in children
A new class of skin test reagents based on Mycobacterium tuberculosis (MTB)-specific antigens has been developed. A phase III clinical trial suggests that C-TST is an effective and safe option for diagnosing pediatric TBI.
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NewsImmunoglobulin replacement therapy shows no reduction in serious infections for patients with CLL
In patients with chronic lymphocytic leukemia (CLL), regular treatment with immunoglobulin replacement therapy was not associated with a reduced risk of serious infections requiring hospitalization, according to a study published in Blood Advances.
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NewsGene therapy may block HIV transmission during breastfeeding, study shows
Delivering broadly neutralizing antibodies against HIV-1 to newborns via gene therapy provided them with multi-year protection from HIV/AIDS infection, according to an animal study.
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NewsGut microbiome transplants show promise for boosting cancer immunotherapy
A comprehensive new review examines the effects of transferring healthy gut bacteria to cancer patients receiving immune checkpoint inhibitors (ICIs).
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NewsClinical trial finds safe, effective treatment for children with severe post-Covid syndrome
Researchers have discovered that a drug designed to treat Celiac disease supported a more rapid return to normal activities for patients following COVID. A small, randomized clinical trialfound the oral drug larazotide was both safe and effective in treating children with MIS-C.
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News‘One and done’: A single shot at birth may shield children from HIV for years, study finds
A new study shows that delivering a single injection of gene therapy at birth may offer years-long protection against HIV, tapping into a critical window in early life that could reshape the fight against pediatric infections in high-risk regions.
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NewsH5N1 found in dairy cattle retains preference for infecting birds, representing low risk to humans
Avian influenza virus from the ongoing outbreak in dairy cattle appears to be keeping its bird-infecting features rather than adapting to better infect other mammals, according to a new study.
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NewsMucosal vaccine shows transient action against Covid-19 variant
Mucosal adenovirus vaccine Ad5-XBB.1.5 boosting elicits nasal IgA and transiently prevents JN.1 wave infection for less than 6 months in real-world settings, a new study reveals.
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NewsEngineers take a closer look at how a plant virus primes the immune system to fight cancer
Scientists took a closer look at how the cowpea mosaic virus (CPMV), unlike other plant viruses, is uniquely effective at activating the body’s immune system to recognize and attack cancer cells.
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NewsGut microbiome may predict “invisible” chronic fatigue syndrome and long COVID
Millions suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) may be closer to personalized care, according to new research that shows how the disease disrupts interactions between the microbiome, immune system, and metabolism.
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NewsTherapeutic vaccine for chronic hepatitis B enters first clinical trial in patients
TherVacB, a novel therapeutic vaccine for chronic hepatitis B, has entered its first clinical trial in patients. A successful phase 1a trial in healthy volunteers saw the vaccine demonstrate a favorable safety profile and trigger the desired immune responses.
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NewsNew study in Ukraine indicates significant lifetime exposure and ongoing transmission of hepatitis B and C viruses among the general population
A nationwide study in Ukraine has found evidence of significant exposure to hepatitis B and C viruses and substantial ongoing circulation among the population, highlighting need for immunisation and regular screening.
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NewsImmunity to seasonal flu protects against severe illness from bird flu in ferrets
A study in ferrets — which have remarkably similar respiratory systems to humans — suggests that widespread immunity to H1N1 seasonal influenza virus may explain why exposure to H5N1 bird flu causes only mild symptoms in humans.
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NewsProbiotics can help or hinder gut recovery after antibiotic treatment
All probiotics are not created equal, according to new research. In a mouse model, researchers found that different probiotic strains can either accelerate or delay the gut microbiome’s recovery after antibiotic treatment.