All Immunology articles – Page 17
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NewsScientists uncover how HPV-positive cancers hide from the immune system — and how to make them visible again
A new study solves a major mystery in cancer immunology by uncovering how HPV hides cancer cells from the immune system by using MARCHF8 to destroy MHC-I, which serves as a warning flag for the immune system.
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NewsNovel biosensing platform enables fingertip blood-based micro-volume t-cell immune monitoring
A new platform, known as Tip Optofluidic Immunoassay Interferon-Gamma Release Assay (TOI-IGRA), could revolutionize how people monitor their immune health. The platform allows for the precise quantification of pathogen-specific T-cell responses using a mere 15-25 μL of fingertip blood.
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NewsTargeting two flu proteins sharply reduces airborne spread
A study in ferrets — which have remarkably similar respiratory systems to humans — suggests that immunity to two proteins in the H1N1 influenza virus sharply reduces transmission.
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NewsPenicillin–streptomycin influences macrophage mechanical properties and microenvironment mechano-sensation
A foundational finding in mechanobiology reveals that penicillin-streptomycin (pen-strep), the antibiotic mixture universally added to mammalian cell culture media, is not a biologically inert antimicrobial agent.
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NewsMothers' exposure to microbes protect their newborn babies against infection
A study dives into new depths to explore why only some babies develop severe infection to common bacteria. The research revealed that the babies that became most severely ill from E. coli infections also had markedly lower levels of germ-fighting antibodies transferred from their mothers.
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NewsHow one flu virus can hamper the immune response to another
Prior exposure to one strain of influenza virus may weaken children’s ability to mount an effective antibody response against their subsequent exposure to a different flu strain, according to a study.
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NewsSevere COVID-19 and flu facilitate lung cancer months or years later, new research shows
Severe COVID-19 and influenza infections prime the lungs for cancer and can accelerate the disease’s development, but vaccination heads off those harmful effects, new research indicates.
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NewsDengue vaccine remains 80.5% effective against severe cases after five years
The tetravalent dengue vaccine was 80.5% effective against severe dengue cases with warning signs over a five-year period. Overall, the vaccine was 65% effective in preventing symptomatic dengue (caused by any serotype) during the five years of monitoring.
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NewsResearchers uncover how bacteria suppress immune defences in stubborn wound infections
A common bacterium can suppress the body’s early warning system in wounds, causing infections to persist and create an environment that allows other bacteria to take hold. Enterococcus faecalis releases large amounts of lactic acid in the wound, which lowers pH, weakens immune cells and prevents them from fighting an infection.
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NewsIsland birds reveal surprising link between immunity and gut bacteria
Scientists have uncovered a hidden link between gut health and the immune system, all thanks to a tiny island bird. They collected the poo of the Seychelles warbler to analyse their gut bacteria – and found that their immune genes influence which gut microbes thrive.
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NewsLow-cost preventive measures could mitigate spread of bacteria causing neonatal mortality
A new study found that a multifaceted infection prevention and control intervention could at least temporarily thwart outbreaks of infections from the Klebsiella pneumoniae bacterium.
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NewsEnteroBiotix announces completion of enrolment in Phase 2a Trial evaluating EBX-102-02 prior to allogeneic stem cell transplantation
EnteroBiotix announced that the investigator-initiated Phase 2a MAST trial has completed its enrolment of 50 adult patients undergoing allogeneic haematopoietic stem cell transplantation (allo-HSCT) for defined haematological malignancies.
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NewsMpox immune test validated during Rwandan outbreak
An antibody test for the infectious disease Mpox was successfully developed during the new clade 1b outbreak in Rwanda, the first time that an assay of its kind has been validated within this setting.
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NewsGut microbes rewrite the rules of cancer immunotherapy
A review synthesizes growing evidence showing that commensal microbes enhance anti-tumor immunity by producing immune-active metabolites, remodeling the tumor microenvironment, and activating key immune cells such as dendritic cells and cytotoxic T cells.
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NewsMicrobe exposure may not protect against developing allergic disease
The “hygiene hypothesis” suggests exposure to diverse types of microbes may protect against developing diseases caused by allergens, but a new study in mice reveals that adults’ exposure to diverse microbes and allergens may in fact worsen certain allergic conditions.
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NewsScientists engineer ‘living eye drop’ to support corneal healing
A proof-of-concept study demonstrates that the harmless eye-dwelling microbe Corynebacterium mastitidis can be genetically modified to secrete an anti-inflammatory therapeutic that promotes healing following corneal injury in a mouse model.
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NewsNew study reveals how hygienic honey bees show unique advantages in fighting infectious pathogens in adult bees
For the first time, research shows that a key social trait in honey bees is linked to measurable physiological advantages that can improve colony survival. The study uncovers how hygienic honey bee colonies mount stronger individual immune defenses against Nosema ceranae.
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NewsHow microbes protect the lungs against allergies
A study has revealed that microbes protect the lungs from subsequently developing allergies and asthma. This long-term protection is “memorized” not by immune system cells but by fibroblasts, structural cells in the lungs.
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NewsFrom gut to lung: A microbial signal that strengthens early immune defense
Researchers report that a gut microbiota–derived metabolite can directly shape immune responses in bacterial pneumonia. Using a Klebsiella pneumoniae infection model, the team demonstrated that butyric acid restores the function of CX3CR1-positive natural killer cells.
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NewsTargeting the gut–lung microbiome to reduce infections in severe pancreatitis
Researchers report new clinical evidence that a fungal probiotic may reduce hospital-acquired infections in patients with severe acute pancreatitis. Patients receiving Saccharomyces boulardii alongside standard enteral nutrition experienced significantly fewer infections than those receiving nutrition alone.