All Immunology articles – Page 13
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NewsNew tool shows how to enter and change pneumocystis fungi
Researchers have reported success in genetically modifying the fungal pathogen Pneumocystis murina. Their approach uses extracellular vesicles from mouse lungs to deliver gene-modifying molecules inside the fungal cells. The modified fungus expressed the introduced genomic modifications.
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NewsFecal microbiota transplantation improves response to immunotherapy in advanced kidney cancer
A new study provides compelling evidence that fecal microbiota transplantation (FMT) can enhance the effectiveness of immunotherapy in patients with advanced metastatic renal cell carcinoma (mRCC).
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NewsIn rare cases, autoantibodies can cause severe reactions to a live-attenuated virus Chikungunya vaccine that has been discontinued in the U.S.
A new study shows that preexisting autoantibodies in a small subset of the population can allow weakened vaccine viruses to escape control, explaining some adverse events tied to one kind of Chikungunya vaccine, which is no longer available in the U.S.
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NewsPreparedness for future pandemics: MERS vaccine candidate shows long-lasting immune response
A new study has shown for the first time that an experimental vaccine against Middle East Respiratory Syndrome (MERS) induces a stable and functional immune response in humans that persists for at least two years after a booster vaccination.
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NewsSerum interleukin-8 can tell pulmonary aspergillosis from bacterial pneumonia in patients with liver failure
Scientists found serum interleukin-8 can be used to differentiate invasive pulmonary aspergillosis from bacterial pneumonia in patients with HBV-associated acute-on-chronic liver failure.
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NewsCOVID-19 viral fragments shown to target and kill specific immune cells
New research shows that after the body’s defenses kill the virus behind COVID-19, leftover digested chunks of SARS-CoV-2 spike protein can target specific immune cells based on their shape. It could explain why certain populations of cells that detect and fight infection are depleted in patients with severe COVID-19.
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NewsAltered brain connection found in people with ME/CFS and Long COVID
People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID experience a disruption to their brain connectivity during a mentally demanding task. New research used ultra-high field MRI technology to investigate the significant reduction in brain connectivity in specific parts of the brain.
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NewsStudy cites link between mental health and long COVID in older women
Older women who have a history of both depression and anxiety had a 78% higher risk of developing long COVID after a SARS-CoV-2 infection, report researchers. Infection rates were not higher; only their risk of complications increased.
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NewsLong COVID brain fog far more common in US than India, other nations
Patients with long COVID-19 in the U.S. report far higher rates of brain fog, depression and cognitive symptoms than patients in countries such as India and Nigeria, according to a large international study.
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NewsStudy suggests link between viral infection and ALS
Researchers have made a potentially game-changing discovery about the development of devastating motor neuron diseases. They identified a specific type of mouse — the CC023 strain — that responds to a viral infection in a way that looks remarkably similar to humans with amyotrophic lateral sclerosis.
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NewsMore than just gut cohabitants: how gut bacteria control immune responses
Bacteria in the human gut can directly deliver proteins into human cells, actively shaping immune responses. The study reveals a new way in which the gut microbiome can influence the human body and may help explain how changes in gut bacteria contribute to inflammatory diseases.
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News3′UTR-derived small RNA couples acid resistance to metabolic reprogramming in Salmonella within macrophages
Salmonella expresses the arginine decarboxylase AdiA, which confers acid resistance by catalyzing an H+-consuming reaction. Researchers have discovered that the 3′-untranslated region (UTR) of adiA mRNA is processed by RNase E into a regulatory small RNA, AdiZ.
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NewsDouble trouble: Tobacco use and Long COVID
Researchers investigating the relationship between Long Covid symptoms and smoking by tobacco type found that certain symptoms correlated with different forms of smoking.
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NewsStudy identifies blood protein albumin as key defense against deadly fungal infection ‘mucormycosis’
A new study has identified albumin as a powerful and previously unrecognized defense against a rare but often fatal fungal infection. Patients with mucormycosis had markedly lower levels of albumin compared with patients suffering from other fungal infections.
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NewsHow a single gene shapes gut health and IBD risk
Two recent studies highlight the role of a gene called PTPN2 in protecting the gut from harmful bacteria linked to inflammatory bowel disease (IBD). When PTPN2 does not function properly, the gut becomes more vulnerable to infection and inflammation.
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NewsChemotherapy rewires gut bacteria to curb metastasis
Researchers report that chemotherapy-induced damage to the intestinal lining alters nutrient availability for gut bacteria, reshaping the microbiota and increasing the production of indole-3-propionic acid (IPA), a tryptophan-derived microbial metabolite.
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NewsOral bacterium may promote breast cancer development and spread
Researchers found that Fusobacterium nucleatum, an oral bacterium commonly associated with periodontal disease, can promote breast cancer initiation, tumor growth and spread by inducing DNA damage and altering cancer cell behavior.
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NewsScientists discover novel immune ‘traffic controller’ hijacked by virus
Researchers have discovered a tissue protein that acts as a central ‘traffic controller’ for immune cells and can be hijacked by a virus to weaken immune responses. Cytomegalovirus (CMV) can hijack this system by producing a protein that blocks CD44 function on stromal cells.
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NewsHidden mpox exposure detected in healthy Nigerian adults, revealing under-recognized transmission
The mpox virus appears to be circulating silently in parts of Nigeria, in many cases without the symptoms typically associated with the disease, according to new research.
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NewsHuman nasal passages defend against the common cold and help determine how sick we get
Researchers demonstrate how the cells in our noses work together to defend us from the common cold and suggest that our body’s defense to rhinovirus—not the virus itself—typically predicts whether or not we catch a cold, as well as how bad our symptoms will be.