All Immunology articles – Page 9
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NewsResearchers uncover how bacteria suppress immune defences in stubborn wound infections
A common bacterium can suppress the body’s early warning system in wounds, causing infections to persist and create an environment that allows other bacteria to take hold. Enterococcus faecalis releases large amounts of lactic acid in the wound, which lowers pH, weakens immune cells and prevents them from fighting an infection.
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NewsIsland birds reveal surprising link between immunity and gut bacteria
Scientists have uncovered a hidden link between gut health and the immune system, all thanks to a tiny island bird. They collected the poo of the Seychelles warbler to analyse their gut bacteria – and found that their immune genes influence which gut microbes thrive.
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NewsLow-cost preventive measures could mitigate spread of bacteria causing neonatal mortality
A new study found that a multifaceted infection prevention and control intervention could at least temporarily thwart outbreaks of infections from the Klebsiella pneumoniae bacterium.
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NewsEnteroBiotix announces completion of enrolment in Phase 2a Trial evaluating EBX-102-02 prior to allogeneic stem cell transplantation
EnteroBiotix announced that the investigator-initiated Phase 2a MAST trial has completed its enrolment of 50 adult patients undergoing allogeneic haematopoietic stem cell transplantation (allo-HSCT) for defined haematological malignancies.
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NewsMpox immune test validated during Rwandan outbreak
An antibody test for the infectious disease Mpox was successfully developed during the new clade 1b outbreak in Rwanda, the first time that an assay of its kind has been validated within this setting.
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NewsGut microbes rewrite the rules of cancer immunotherapy
A review synthesizes growing evidence showing that commensal microbes enhance anti-tumor immunity by producing immune-active metabolites, remodeling the tumor microenvironment, and activating key immune cells such as dendritic cells and cytotoxic T cells.
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NewsMicrobe exposure may not protect against developing allergic disease
The “hygiene hypothesis” suggests exposure to diverse types of microbes may protect against developing diseases caused by allergens, but a new study in mice reveals that adults’ exposure to diverse microbes and allergens may in fact worsen certain allergic conditions.
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NewsScientists engineer ‘living eye drop’ to support corneal healing
A proof-of-concept study demonstrates that the harmless eye-dwelling microbe Corynebacterium mastitidis can be genetically modified to secrete an anti-inflammatory therapeutic that promotes healing following corneal injury in a mouse model.
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NewsNew study reveals how hygienic honey bees show unique advantages in fighting infectious pathogens in adult bees
For the first time, research shows that a key social trait in honey bees is linked to measurable physiological advantages that can improve colony survival. The study uncovers how hygienic honey bee colonies mount stronger individual immune defenses against Nosema ceranae.
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NewsHow microbes protect the lungs against allergies
A study has revealed that microbes protect the lungs from subsequently developing allergies and asthma. This long-term protection is “memorized” not by immune system cells but by fibroblasts, structural cells in the lungs.
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NewsFrom gut to lung: A microbial signal that strengthens early immune defense
Researchers report that a gut microbiota–derived metabolite can directly shape immune responses in bacterial pneumonia. Using a Klebsiella pneumoniae infection model, the team demonstrated that butyric acid restores the function of CX3CR1-positive natural killer cells.
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NewsTargeting the gut–lung microbiome to reduce infections in severe pancreatitis
Researchers report new clinical evidence that a fungal probiotic may reduce hospital-acquired infections in patients with severe acute pancreatitis. Patients receiving Saccharomyces boulardii alongside standard enteral nutrition experienced significantly fewer infections than those receiving nutrition alone.
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NewsResearchers identify ‘neuroimmune signature’ that can predict viral hepatitis complications
A network of genes linked to the nervous and immune systems can predict cancer risk and even explain symptoms such as fatigue and depression resulting from viral hepatitis infection.
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NewsScientists develop shape-shifting scaffold that fights infection and rebuilds bone
Scientists have developed a body-temperature–responsive, 3D-printed shape-memory scaffold coated with a metal–polyphenol network to treat infectious bone defects. It is designed to adapt to irregular bone defects while providing antibacterial activity, immune regulation, and osteogenic support.
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NewsBacteria found in mouth and gut may help protect against severe peanut allergic reactions
One of the big mysteries in food allergy is why two people with similar levels of peanut specific antibodies can react so differently. A new study shows for the first time how gut bacteria break down parts of an allergenic food and influence how a person reacts to peanuts.
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NewsStudy finds natural fungal supplement improves COVID-19 vaccine response
Researchers have found that a natural fungal supplement taken at the time of COVID-19 vaccination reduced short-term vaccine side effects and helped antibodies last longer in people who had not previously been exposed to the virus.
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NewsEditing for timing, not overdrive: A new genetic route to fire blight resistance in apple
Fire blight remains one of the most destructive bacterial diseases threatening global apple production. A new study identifies a family of inducible lectin genes, MdAGGs, as critical components of apple immune defense and demonstrates that their precise activation timing is key to effective resistance.
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NewsNanoparticle vaccine approach takes on a new target: Hepatitis C virus
Scientists have engineered a native-like, stabilized version of Hepatitis C virus’s E1E2 complex and used it to build a nanoparticle-based vaccine candidate. It uses a technology called self-assembling protein nanoparticles, which organizes copies of the proteins into virus-like clusters that the immune system can recognize.
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NewsScientists identify therapeutic target that would curb the spread of coronaviruses
Coronaviruses not only use the machinery of the human cells they infect: they modify it to achieve optimal conditions to produce viral proteins and thus spread more quickly, according to a study identifying enzymes that modify transfer RNAs as key elements for coronavirus infection.
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NewsEpigenetic rewiring fuels potato susceptibility to late blight
Scientists performed whole-genome bisulfite sequencing and RNA sequencing on the widely cultivated potato cultivar Qingshu No.9 following Phytophthora infestans infection, uncovering dynamic DNA methylation shifts that correlate with large-scale transcriptional reprogramming and immune suppression.