All Immunology articles – Page 9
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NewsTuberculosis risk: promising approaches for screening and prediction
It is currently difficult to detect TB in its early stages, or predict who will go on to have TB, and therefore preventive treatment is not widely used. Researchers assessed whether a blood-based 3-gene host-response test can detect active tuberculosis and help predict future disease.
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NewsHead impacts associated with altered gut microbiome in football players
Non-concussive head impacts—hits to the head that don’t cause clinically detectable symptoms—are correlated with subsequent changes to the gut microbiome in a small sample of US collegiate football players, according to a new study.
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NewsScientists discover how HIV hijacks a cellular ‘gateway’ to infect resting immune cells
New research reveals that when HIV spreads directly between T-cells it triggers a molecular signalling chain that temporarily ‘unlocks’ the nuclear pore complex, allowing the HIV virus and capsid to enter and integrate into the host’s DNA.
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NewsWhy feeling sick may be important for surviving infection
In a new perspective, scientists propose a different way of thinking about sickness symptoms: what if these behaviors are part of an integrated immune strategy that operates across scales — from individual cells to tissues and organs, to the whole organism — and helps promote survival?
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NewsGut microbes actively support immunity in people living with HIV
A new study shows that gut microbes help bolster immunity in people living with HIV – and that, one day, these microbes may be harnessed to protect this population from infections driven by immune deficiency.
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NewsIn mice, viruses gain virulence in some individuals, depending on genetics and sex
New research demonstrates that some hosts appear to serve as “evolutionary accelerators” that could enable viruses to gain virulence more quickly.
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NewsStudy confirms effectiveness of medicinal plant against SARS-CoV-2 virus
A study has revealed that galloylquinic acids extracted from the leaves of Copaifera lucens Dwyer, a tree endemic to Brazil primarily found in the Atlantic Forest, have a multi-targeted effect against SARS-CoV-2, the virus that causes COVID-19.
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NewsYour nose is a battlefield
Scientists have discovered that FluMist can trigger an immune response directly in nasal tissue in adults. The vaccine trains immune cells in the upper nasal passages to recognize and fight influenza virus infection. This immune response stays in the upper airways and can’t be detected via blood samples.
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NewsNew study shows antibodies need a strong core — not just grip — to fight SARS-CoV-2
Researchers used advanced computer simulations to investigate how antibody–virus complexes respond to mechanical forces across multiple SARS-CoV-2 variants, including the original 2019 strain and Omicron subvariants BA.4 and JN.1.
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NewsVaccine strategy induces broadly neutralising HIV antibodies
Researchers have developed a new vaccine strategy that has generated antibodies capable of neutralising highly divergent HIV variants. The study provides new insights into how the immune system can be guided towards a particularly protected part of the virus.
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NewsNew study suggests seasonal flu vaccines may reduce severity of H5N1 bird flu infections
Researchers have found that seasonal influenza vaccines in routine global use may significantly reduce the risk of death from H5N1 infection. The findings that readily available tools may offer protection while the world races to develop more targeted solutions.
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NewsPlasmodium uses its own PI3K to suppress eat-me signal and evade host immune clearance
A study finds that Plasmodium PI3K actively suppresses the externalization of phosphatidylserine on the surface of infected erythrocytes. When the activity of parasite PI3K was chemically inhibited or genetically disrupted, phosphatidylserine exposure on infected red blood cells increased markedly.
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NewsHow the immune system battles lifelong viral infections acquired at birth
Millions of people worldwide carry viral infections they acquired at birth, often for life. For a long time it was assumed that the immune system hardly fights these pathogens. Researchers show that the body’s defenses do indeed act against the virus.
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NewsNew study suggests reduced newborn hepatitis B vaccination coverage may increase infant infections
Researchers found that lower vaccination coverage among infants born to unscreened mothers was associated with a substantial increase in HBV infections.
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NewsResearchers discover new mosquito-specific viruses
A new study looked at mosquitoes’ immune response to discover many more insect viruses. Researchers hope to someday use the mosquitoes’ own immune system to battle some of the most pervasive and antagonistic human viruses.
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NewsImmune cells in the nose slow influenza virus
Memory cells in the nose slow the influenza virus as soon as it enters the body. They reduce viral levels and may help protect against more severe illness, according to a study that may help guide the development of better influenza vaccines.
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NewsAssociation of changes in portal insulin with immunometabolism during and after hepatitis C virus infection
A new study aims to investigate the relationship between insulin, the gut-liver axis, and immunometabolic changes in patients with hepatitis C virus. Lower portal insulin during HCVi is associated with changes consistent with altered pancreatic insulin secretion and decreased hepatic insulin extraction.
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NewsSeparating signal from noise: How African biostatisticians are reshaping the fight against malaria
Biostatistics is unlocking smarter malaria solutions, linking parasite diversity, vaccines, and human behaviour to drive more effective prevention and protection.
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NewsScientists highlight the cost of delaying childhood vaccination
Delaying hepatitis B vaccination after birth increases infections among newborns and decreases their survival rates and quality of life. A new study found that the longer the delay, the higher the cost in human life and health care.
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NewsResearchers deploy phage therapy in new frontier against antimicrobial resistant infectious diseases
A revelatory treatment for patients with life-threatening infectious diseases is being pioneered in Melbourne. VICPhage, a clinical partnership between The Alfred and Monash, is one of the first in Australia to offer end-to-end capacity in phage therapy to treat some of the most challenging infections.