All Immunology articles – Page 6
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NewsResearchers investigate the underlying causes of post-treatment Lyme disease syndrome
With an estimated one million Americans afflicted with post-treatment Lyme disease syndrome, newly funded research seeks to determine whether the condition is triggered by a persistent autoimmune response, and if a test can be devised to pinpoint who is more likely to develop it.
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NewsThousands of young people to be offered two-dose MenB vaccine ahead of autumn
Thousands of young people across England will get protection against meningococcal B disease (MenB) through a one-off vaccination programme launching ahead of the 2026 academic year.
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NewsLouse-borne relapsing fever: How the pathogen evades the immune system
A research team has now identified and characterized five closely related proteins that are crucial for the survival of Borrelia recurrentis in the human body. These so-called Chi proteins appear to have evolved from a common ancestor and are therefore considered homologous.
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NewsFasting-mimicking diet reduces gum disease inflammation
A new study highlights how lifestyle modifications could be important alongside plaque control in managing gum disease. While fasting has been linked to reduced inflammation around the body, this is the first to establish a relationship with gum disease too.
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NewsFrom pest to useful tool: How wax moth larvae can help reduce animal testing in research
A new study indicates greater wax moth larvae show great potential as a robust and ethically acceptable in vivo model for studying pathogenic bacteria.
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NewsFirst-in-human clinical trial shows promising results for new Lassa fever vaccine
Researchers have reported encouraging results from an early clinical trial that tested a new dual vaccine against Lassa fever and rabies. The study found that the vaccine was safe and induced immune responses against both viruses. There are currently no vaccines against Lassa fever on the market.
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NewsAccelerating chikungunya vaccine development in Africa: Launch of the ACT-CHIK Project
Funded by the Global Health EDCTP3 Joint Undertaking, a new €15.3 million project coordinated by Institut Pasteur brings together seven partners across four continents to advance clinical trials and prepare for the manufacturing of a chikungunya vaccine in Africa.
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NewsResearch team awarded NIH grant to study early immune determinants of human tuberculosis infection
A research team was awarded a 5-year, $3.8 million grant to study early immune responses in the lung and how they influence tuberculosis infection outcomes. The program focuses on how lung immune cells called macrophages influence the earliest stages of tuberculosis infection.
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NewsTime for an AI checkup: Flaw found in machine learning for sepsis treatment
Researchers found a flaw in many peer-reviewed studies using the AI method known as reinforcement learning as a theoretical guide for the treatment of sepsis. If these flawed systems for sepsis treatment were deployed in a healthcare setting, they would recommend either overtreatment or undertreatment in nearly half of patient states.
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NewsMost cases of HIV persistence in blood following treatment explained by defective copies of the virus
A study based on blood samples strongly suggests that most persistent cases of viral detection, despite ideal HIV drug therapy, are not due to virus transmission or a rebound of active disease.
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NewsResearchers develop new vaccine adjuvant that could make it easier to eradicate polio
Researchers have now come up with a way to modify the injectable polio vaccine so that it can also promote a mucosal immune response. This vaccine could help to achieve polio eradication while avoiding the risks of the oral polio vaccine.
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NewsT cells may be key to stopping measles virus—and its deadly relatives
Scientists have discovered how T cells target paramyxoviruses, a viral family that includes measles virus and Nipah virus. Instead of vaccinating against one virus at a time, the researchers found that activating “cross-reactive” T cells may protect against the wider paramyxovirus family.
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NewsScientists recreate enterovirus infection in a new model of the human intestine
A miniaturized, biomimetic model of the human intestine successfully reproduced long-term enterovirus A71 (EV-A71) infection, report researchers. Using this innovative platform, they shed light on how this virus grows in the intestine without triggering a strong immune response.
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NewsPopular GLP-1 drug may slow down biological aging in people with HIV
A new study provides the first randomized, placebo-controlled clinical evidence that semaglutide, a widely used GLP-1 drug, slows down the accumulation of biological aging markers in the DNA of adults with HIV.
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NewsBiomaterial made from jackfruit latex is a promising treatment for periodontitis
Researchers have developed a biomaterial containing jackfruit latex, pomegranate peel extract, and simvastatin that shows promising efficacy in treating periodontitis. This chronic inflammatory disease of infectious origin leads to the progressive destruction of the tissues supporting the teeth, resulting in bone resorption and loss of attachment.
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NewsStudy identifies serious infection risks linked to targeted cancer therapies
A major real-world study has found serious blood-related side effects associated with antibody-drug conjugates, an increasingly important class of targeted cancer therapies. Some ADCs were associated with substantial rates of severe neutropenia – dangerously low levels of infection-fighting white blood cells – and related complications.
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NewsNew study identifies key warning signs for infection after ankle fracture surgery in older patients
A new study of which patients are most at risk of a fracture-related infection post ankle surgery finds that low protein levels in the blood is the single strongest patient-related risk factor, making infection nearly 18 times more likely. Chronic alcohol abuse and failure to follow post-operative instructions each raise the risk more than fivefold.
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NewsBehind the diagnosis: How laboratory testing guided a complex histoplasmosis case
A diagnosis of histoplasmosis forced a teenager with juvenile arthritis onto an uncertain path, one defined by months of treatment, recovery, and a long-term course of antifungal therapy expected to last up to three years. Histoplasma capsulatum, a dimorphic fungus that causes histoplasmosis, found its way into her lungs.
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NewsPost-discharge antibiotics may offer limited benefit after pediatric appendicitis
Acute appendicitis is one of the most common surgical emergencies among children, and complicated acute appendicitis (CAA), including perforated or gangrenous disease, carries a higher risk of infection and longer hospitalization. While intravenous antibiotics during hospitalization are standard practice, the role of oral home antibiotics (OHA) after discharge remains controversial. ...
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NewsHealth researchers call for support to develop pandemic prevention
The Vanderbilt Center for Antibody Therapeutics has received large-scale government grants and contracts to fund the discovery of human antiviral antibodies. The problem is the next step — finding corporate partners to develop the antibodies through human testing.