All Immunology articles – Page 4
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Researchers map key human proteins that power coronavirus replication, pointing to new treatment strategies
Scientists have pinpointed dozens of human proteins that SARS-CoV-2 needs to complete its full life cycle, from entering a cell to replicating and releasing new viral particles.
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Gray seals perplex scientists with lack of response to flu infection
Something strange happens when two kinds of seals living in the waters around Cape Cod get infected with influenza – harbor seals get sick but gray seals don’t. This perplexing phenomenon led scientists to investigate if a difference in a piece of the immune system called cytokines could be responsible for this difference.
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Protein discovery gives new hope for longer COVID protection
Scientists have discovered that the body’s immune system strongly reacts to an internal protein from SARS-CoV-2, the virus that causes COVID-19, which mutates less frequently than the surface-spike protein currently targeted by vaccines.
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Antibody-making cells reveal new function in response to flu infection
A study has uncovered a new function of the immune cells that are known for making antibodies. Researchers determined that, in response to flu infection, a specialized set of B cells produce a key signaling molecule that the immune system needs to develop a robust, long-term response to fight off infections.
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Study suggests link between hepatitis B immunity and lower risk of developing diabetes
A research study shows that overall HBV immunity is linked with a 15% lower risk of diabetes, with higher protection in younger people and those with higher immunity shown by higher antibody levels.
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Therapeutic vaccination against HPV-related tumors: Nanoparticles make the difference
Researchers have developed a therapeutic vaccination concept that can mobilize the immune system to target cancer cells. Virus peptides coupled to silica nanoparticles can elicit effective T-cell responses against HPV-related tumors. In a mouse model, the nanoparticle-based vaccine was able to partially or completely suppress HPV-related tumors.
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One shot of RSV vaccine effective against hospitalization in older adults for two seasons
One shot of an RSV vaccine protects adults ages 60 or older from RSV-associated hospitalization and critical illness during two consecutive RSV seasons, according to a new study.
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CARB-X backs neonatal sepsis diagnostic platform by Quantamatrix
CARB-X has awarded QuantaMatrix Inc. US$2.85M to execute a workplan to develop its rapid diagnostic platform to detect sepsis, especially in vulnerable neonates. The test aims to deliver results within just 6 hours from very small blood samples of 1 to 2 milliliters.
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Guideline on respiratory infections in leukemia revised
People with leukemia have a weakened immune system due to the disease itself and treatment, which leads to an increased susceptibility to infections. In a revised guideline, experts summarize the findings of the past ten years on all viruses that cause respiratory infections.
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MERIT grant awarded to study cure for HIV
A scientific team has received an NIH MERIT Award to provide long-term grant support to study a handful of people who have managed to clear HIV after a stem cell transplant and those who did not.
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Pertussis resurgence in Tuscany outlines importance of timely vaccination in Italy
Research analysing 2016-2024 data from all pertussis-related hospitalisations in Tuscany, Italy, finds a ninefold increase in pertussis cases in 2024 among children and adolescents.
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Seroprevalence 36 months after a single-dose bivalent HPV vaccination among nine to fifteen-year-old girls
A single-dose bivalent HPV vaccine induces sustained immunity in Bangladeshi adolescent girls, with lower HPV16 seropositivity among older girls and those in higher grades, with higher HPV18 seropositivity linked to lower household income.
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Alcohol opens the floodgates for bad bacteria
Scientists have found that chronic alcohol use impairs the production of a key cellular signaling protein that helps keep gut bacteria within the gut. Without this guardrail in place, bacteria from the gut can more easily migrate to the liver, exacerbating liver damage caused by alcohol.
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Kiss goodbye to deadly disease – new research finds ‘Pac-Man’ antibodies for killer parasite
Researchers have successfully produced antibodies that kill the parasite carried by the ‘kissing bug’ that causes the potentially deadly Chagas disease. The research is a vital step towards the development of the first effective vaccine.
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Global analysis reveals overlooked hotspots at risk for long COVID due to early disability burdens
An international team of researchers has conducted the most comprehensive global-to-local analysis to date on long COVID risk, using disability data from the height of the pandemic to identify vulnerable populations.
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Scientists identify three potent human antibodies against mpox, paving the way for new protective therapies
Researchers have discovered three powerful monoclonal antibodies from a person who had previously been infected with mpox (formerly known as monkeypox).
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Scientists discover how cells use a secret weapon to fight off some pathogens
New research shows that mitochondria detect invading pathogen Toxoplasma gondii and ramp up competition for vitamin B9, depriving it of the nourishment it needs to grow. A researcher noticed that the amount of mitochondrial DNA in a mitochondrion increased during infection.
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Common cold may protect against COVID-19 according to researchers
A new study has found that recent infection with the common cold — often caused by rhinoviruses — may offer temporary protection against infection with SARS-CoV-2, the virus that causes COVID-19.
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Mouth to gut bacteria migration explains why smoking is good for inflamed bowels
Researchers have discovered why smoking tobacco helps people suffering from ulcerative colitis. The study shows that smoking produces metabolites that encourage bacteria from the mouth to grow in the large intestines where they trigger an immune response.
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Maternal antibodies in breast milk regulate early immune responses in mouse gut
In mice, maternal antibodies ingested in breast milk in the first week after birth help to regulate immune responses in the newborn gut, according to a new study.