All Immunology articles
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A trial HIV vaccine triggered elusive and essential antibodies in humans
An HIV vaccine candidate triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.
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Advances in priming B cell immunity against HIV pave the way to future HIV vaccines, new studies show
Scientists have made several advances in the design of a class of HIV vaccines that could offer broad protection against the virus, according to four new research papers published this week.
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Study provides new insights into phage therapy design
Results from a new study are providing new insights into the therapeutic potential of bacteriophage (phage) therapy for treating diseases like cystic fibrosis (CF).
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GPS-like system shows promise as HIV vaccine strategy to elicit critical antibodies
Researchers have developed a vaccine approach that works like a GPS, guiding the immune system through the specific steps to make broadly neutralizing antibodies against HIV.
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SARS-CoV-2 and type 1 diabetes in children: new study aims to explore the relationship
A new study will investigate whether vaccination against SARS-CoV-2 in the first year of life can protect children who have an increased genetic risk for type 1 diabetes from developing the condition.
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A third Covid vaccine dose improves defence for some clinically extremely vulnerable patients
A major clinical trial has found that an additional COVID 19 vaccine dose led to the majority of clinically extremely vulnerable people mounting defensive antibodies against Covid-19.
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Key role found for gut epithelial cells in the defense against deadly diarrheal infections
A newly identified subset of intestinal epithelial cells act as both the major target and a key responder in a mouse model of gut infection by the bacteria Citrobacter rodentium.
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Researchers discover link between breast changes and UTIs
Scientists have found that UTIs in mice can provoke a bodily response that results in structural changes in breast tissue. Remarkably, these changes are reversible once the infections are resolved.
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Study identifies immunity threshold for protection against COVID-19 in children
Researchers have found rather than antibodies, other arms of the immune system – T cells and memory B cells – provide durable protection against symptomatic SARS-CoV-2 infection in children.
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New strategy could lead to universal, long-lasting flu shot
Researchers have opened a new avenue in the attack against influenza viruses by creating a vaccine that encourages the immune system to target a portion of the virus surface that is less variable.
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New study on immune cells interaction unlocks novel treatment targets for Chikungunya virus
Insights from this study open doors for the development of new drugs targeting immune cells to combat CHIKV and similar viruses.
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Staying current with COVID-19 vaccinations helps combat emerging variants
The study is among the first to test in a biosafety level 3 laboratory whether vaccine-elicited antibodies block infection of a live virus.
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Experts developing immune-enhancing therapies to target tuberculosis
Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body’s own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.
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Lower dose of mpox vaccine is safe and generates six-week antibody response equivalent to standard regimen
A dose-sparing intradermal mpox vaccination regimen was safe and generated an antibody response equivalent to that induced by the standard regimen at six weeks (two weeks after the second dose), according to new findings.
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Study confirms effectiveness of bivalent COVID-19 vaccine
A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, according to a new study.
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Experimental NIH malaria monoclonal antibody protective in Malian children
One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country’s six-month malaria season, according to the results of a mid-stage clinical trial.
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Vitamin D availability enhances antitumor microbes in mice
Dietary vitamin D modulates the gut microbiome to enhance the response to cancer immunotherapies, according to a new study in mice.
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Researchers use AI to improve Alzheimer’s treatment through the ‘gut-brain axis’
Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer’s disease.
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Pathogens deploy speargun nanomachine to spread unrecognized in the body
Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In their study, they reveal the crucial role of a bacterial nanomachine in this infection process.
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Gut bacteria can change their ‘software’ in reaction to inflammation
New research reveals an ingenious adaptation strategy used by gut microbes, allowing them to dynamically reprogram gene expression based on local conditions like inflammation or viral attacks.