All Immunology articles
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Vaccinated patients hospitalized with COVID-linked acute kidney injury less likely to need dialysis after discharge
Vaccinated patients hospitalized with COVID-19 who developed acute kidney injury had better outcomes than unvaccinated patients with the same condition, new research suggests. The study found vaccinated patients were less likely to stay on dialysis after discharge, and more likely to survive, than unvaccinated patients.
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Ribosome profiling identifies thousands of new viral protein-coding sequences
With the help of a technique called Massively Parallel Ribosome Profiling (MPRP), scientists have identified more than 4000 open reading frames (ORFs) across 679 human-associated viral genomes.
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People with inflammatory RMD tolerate zoster vaccine well, study finds
New work presented at the 2025 annual EULAR congress in Barcelona focuses on the recombinant zoster vaccine (RZV), which contains recombinant glycoprotein E – the major target of CD4+T-cells. The abstract describes the tolerability and safety of RZV in patients with inflammatory rheumatic and musculoskeletal diseases (iRMD).
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Study indicates that severe forms of COVID-19 infection in children may increase cardiovascular disease risks
Scientists analysed blood samples from 147 children across different COVID-19 conditions and identified significant metabolic disruptions beyond the acute viral infection phase. These alterations affect how the body processes fats (triglycerides and cholesterol) critical to healthy heart structure.
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Scholars take a new look at controversial Stateville prison malaria research 75 years ago
Medical ethicists are shining a light on a buried part of the malaria research conducted on inmates at Illinois’ Stateville Penitentiary 75 years ago.
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A promising therapeutic agent for treating excessive inflammation due to COVID-19
Researchers show that iguratimod, a rheumatoid arthritis drug, reduces COVID-19-induced inflammation in mice without suppressing antiviral immunity.
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SARS-CoV-2 protein found to spread between cells, triggering immune attack on healthy cells
A new study reveals that the SARS-CoV-2 nucleocapsid protein can spread from infected to uninfected cells, triggering an immune response that mistakenly targets healthy cells.
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Ultra-selective aptamers give viruses a taste of their own medicine
Inspired by the way viruses attach to cells, scientists have developed a method for engineering ultra-selective aptamers. The synthetic molecules bind to targets like viral spike proteins, making them useful for biomedical diagnostics and treatments.
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New platform can diagnose infectious disease immune protection using one drop of fingertip blood
Researchers have developed a compact diagnostic platform that can evaluate antibody protection against COVID-19 using only a single microliter of fingertip blood. It delivers a comprehensive immune profile in just 40 minutes.
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Global study: COVID-19 and adenoviral vaccines tied to GBS risk, not mRNA vaccines
A large-scale study in a population covering more than 230 million people sheds light on the relationship between Guillain-Barré syndrome after COVID-19 vaccines or SARS-CoV-2 infection.
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Researchers uncover genetic keys to the increasing threat of H9N2 avian influenza
A new study has uncovered significant genetic and antigenic diversity among H9N2 avian influenza viruses (AIVs) circulating in poultry across China, highlighting the growing public health risk posed by H9N2 AIVs.
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Large-scale immunity profiling grants insights into flu virus evolution
A new study has shown that person-to-person variation in antibody immunity plays a key role in shaping which influenza (flu) strains dominate in a population.
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Scientists unravel the growth regulation mechanisms of core human gut microbiota
Researchers conducted a large-scale analysis of gut microbiome data from Korean individuals and discovered that Akkermansia muciniphila, a top candidate for microbiome-based therapeutics, is not a single species but consists of four distinct subtypes.
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Study uncovers how certain antibodies help fight tuberculosis
Researchers collected the largest library of monoclonal antibodies to Mycobacterium tuberculosis (Mtb) and identified specific antibody features that significantly limit its growth.
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Earlier measles vaccine could help curb global outbreak
The global measles outbreak must trigger an urgent debate into whether a vaccine should be recommended earlier to better protect against the highly contagious disease during infancy, a new review states.
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Researchers reveal the cellular network behind oral tolerance
A new study has resolved a long-standing paradox surrounding oral tolerance and revealed the cellular network responsible. These findings may clarify this network’s malfunctions, which underlie food allergies and sensitivities and disorders such as celiac disease.
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Researchers engineer a herpes virus to turn on T cells for immunotherapy
Researchers have identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival - a promising tool in the fight against cancer.
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Microbial proteins reveal chemical signatures of body sites and inflammation
A new study shows that protein sequences associated with microbial communities in the human gut have uniquely low stoichiometric water content and undergo counterintuitive chemical shifts toward chemically reduced states during inflammation.
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Zika virus uses cells’ ‘self-care’ system to turn against host
A new study reveals the biological secret to the Zika virus’s infectious success: Zika uses host cells’ own ‘self-care’ system of clearing away useless molecules to suppress the host proteins that the virus has employed to get into those cells in the first place.
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SARS-CoV-2 corrupts some white blood cells to suppress immune system, suggesting path to severe COVID
A study found that neutrophils may be altered by SARS-CoV-2, the virus that causes COVID-19, to cease their normal function of destroying pathogens in the body and, instead, significantly inhibit other immune cells critical for fighting the virus.