All Immunology articles – Page 5
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News
Ultra-selective aptamers give viruses a taste of their own medicine
Inspired by the way viruses attach to cells, scientists have developed a method for engineering ultra-selective aptamers. The synthetic molecules bind to targets like viral spike proteins, making them useful for biomedical diagnostics and treatments.
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New platform can diagnose infectious disease immune protection using one drop of fingertip blood
Researchers have developed a compact diagnostic platform that can evaluate antibody protection against COVID-19 using only a single microliter of fingertip blood. It delivers a comprehensive immune profile in just 40 minutes.
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Global study: COVID-19 and adenoviral vaccines tied to GBS risk, not mRNA vaccines
A large-scale study in a population covering more than 230 million people sheds light on the relationship between Guillain-Barré syndrome after COVID-19 vaccines or SARS-CoV-2 infection.
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Researchers uncover genetic keys to the increasing threat of H9N2 avian influenza
A new study has uncovered significant genetic and antigenic diversity among H9N2 avian influenza viruses (AIVs) circulating in poultry across China, highlighting the growing public health risk posed by H9N2 AIVs.
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Large-scale immunity profiling grants insights into flu virus evolution
A new study has shown that person-to-person variation in antibody immunity plays a key role in shaping which influenza (flu) strains dominate in a population.
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Scientists unravel the growth regulation mechanisms of core human gut microbiota
Researchers conducted a large-scale analysis of gut microbiome data from Korean individuals and discovered that Akkermansia muciniphila, a top candidate for microbiome-based therapeutics, is not a single species but consists of four distinct subtypes.
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Study uncovers how certain antibodies help fight tuberculosis
Researchers collected the largest library of monoclonal antibodies to Mycobacterium tuberculosis (Mtb) and identified specific antibody features that significantly limit its growth.
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Earlier measles vaccine could help curb global outbreak
The global measles outbreak must trigger an urgent debate into whether a vaccine should be recommended earlier to better protect against the highly contagious disease during infancy, a new review states.
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Researchers reveal the cellular network behind oral tolerance
A new study has resolved a long-standing paradox surrounding oral tolerance and revealed the cellular network responsible. These findings may clarify this network’s malfunctions, which underlie food allergies and sensitivities and disorders such as celiac disease.
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Researchers engineer a herpes virus to turn on T cells for immunotherapy
Researchers have identified herpes virus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival - a promising tool in the fight against cancer.
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Microbial proteins reveal chemical signatures of body sites and inflammation
A new study shows that protein sequences associated with microbial communities in the human gut have uniquely low stoichiometric water content and undergo counterintuitive chemical shifts toward chemically reduced states during inflammation.
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Zika virus uses cells’ ‘self-care’ system to turn against host
A new study reveals the biological secret to the Zika virus’s infectious success: Zika uses host cells’ own ‘self-care’ system of clearing away useless molecules to suppress the host proteins that the virus has employed to get into those cells in the first place.
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SARS-CoV-2 corrupts some white blood cells to suppress immune system, suggesting path to severe COVID
A study found that neutrophils may be altered by SARS-CoV-2, the virus that causes COVID-19, to cease their normal function of destroying pathogens in the body and, instead, significantly inhibit other immune cells critical for fighting the virus.
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Careers
How structural imaging is revolutionising vaccines
Dr. Peijun Zhang, Director of the Electron Bio-Imaging Centre (eBIC) at the UK’s national synchrotron facility Diamond Light Source, reveals how Cryo-ET is powering some of the most important advances in vaccine research.
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Ancient remains reveal how a pathogen began to use lice – not ticks – to infect humans
Researchers have analysed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through lice rather than ticks, and how it gained and lost genes in the process.
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Tuberculous meningitis: study shows that metabolism drives mortality
A new study suggests that dysregulated β-oxidation may be an important and potentially modifiable contributor to mortality in tuberculous meningitis.
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Post-COVID syndrome: new insights into connection between gut health and fatigue
A new study shows that post-COVID syndrome patients have altered inflammatory markers and a disturbed intestinal barrier, which could contribute to the development of post-viral fatigue.
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A gene variant increases the risk of long COVID
An international team of researchers has found a genetic link to long-term symptoms after COVID-19. The identified gene variant is located close to the FOXP4 gene, which is known to affect lung function.
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Organoids reveal the secrets of bat immunity
Researchers successfully infected both bat organoids and human airway organoids with the Marburg virus. Compared to the human models, bat organoids exhibited a significantly higher baseline antiviral immune activity even before infection.
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Selenium exposure during pregnancy may reduce childhood streptococcal infections
Higher maternal selenium levels during pregnancy were associated with a lower risk of streptococcal infections in children, a new study shows, suggesting a potential protective effect.