All Immunology articles – Page 3
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Taking the sting out of ulcerative colitis
Researchers reveal that the intestinal flora works in combination with the mutated OTUD3 gene and STING signaling to aggravate ulcerative colitis.
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Researchers uncover the antiviral potential of defensins
Scientists have discovered that certain defensins - tiny proteins with powerful antimicrobial potential - could block the virus that causes COVID-19 (SARS-CoV-2) from entering human cells.
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TB bacteria play possum to evade vaccines
Scientists studied how the TB bacterium evades an immune system primed to destroy it. Their genetic study in mice reveals that TB bacteria can essentially play dead to outlast the immune response.
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Emerging viral threats combatted by a potent new dual lipid kinase inhibitor
Lipid kinases play a critical role in cell signalling and membrane trafficking by phosphorylating lipid molecules in the body. The inhibition of two of these lipid kinases, PIKfyve and PIP4K2C, could be beneficial in the treatment of diseases, particularly emerging viruses.
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Early antibiotics alter immune function in infants- but a gut-derived molecule could help restore it
A new study has found that early-life exposure to antibiotics can impair an infant’s developing immune system, and that a naturally occurring metabolite may hold the key to reversing that damage.
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Acupuncture eases opioid therapy, rebalancing gut microbiota, study shows
Acupuncture significantly lowers methadone doses for people undergoing treatment for opioid use disorder, while restoring antiviral immune responses and rebalancing gut microbiota and metabolism, according to a new study.
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Scientists discover compounds that help cells fight a wide range of viruses
Researchers have identified compounds that can fight off viral infection by activating a defense pathway inside host cells. These compounds, they believe, could be used as antiviral drugs that work against not just one but any kind of virus.
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Long Covid lessons: New cell therapy boosts immune recovery in cats with severe coronavirus
Feline infectious peritonitis is a serious and historically fatal disease in cats caused by a coronavirus. Scientists have found that mesenchymal stromal cells, or MSC therapy, in combination with antiviral drugs, helped cats’ immune systems recover and reduced systemic inflammation.
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Aluminum exposure from childhood vaccines not linked to increased risk of autoimmune, allergic, or neurodevelopmental disorders
A nationwide cohort study of Danish children has found no evidence supporting an increased risk for autoimmune, atopic or allergic, and neurodevelopmental disorders associated with exposure to early childhood aluminum-adsorbed vaccines.
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New insights into malaria: Proteins in the blood can reveal the severity of the disease
Researchers have identified over 250 proteins that are strongly affected by malaria, which could help predict the severity of the disease and thus enable faster treatment for the most critical patients.
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Tiny chip speeds up antibody mapping for faster vaccine design
By analyzing just a drop of blood, this microchip gives researchers quicker-than-ever insight into how a person’s antibodies are interacting with a virus or other pathogen.
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Cohort data from Denmark show real-world evidence of stable protection against HPV-related cervical cancer
Denmark has been offering free vaccination against human papillomavirus (HPV) to girls since 2008. New data show vaccination has effectively reduced infections with cancerogenic HPV 16/18 types covered by the vaccine, indicating population immunity.
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Researchers develop mRNA-based vaccine against a deadly plague-causing bacterium
Researchers have used the platform developed for COVID-19 vaccines to create the world’s first mRNA-based vaccine against the deadly, antibiotic-resistant bacterium behind pneumonic plague.
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New strategy developed to engineer high-affinity receptor-containing antibodies against malaria
Researchers have introduced an innovative approach to developing high-affinity receptor-containing antibodies in vitro, offering a promising strategy to combat malaria.
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Prairie dogs carry genes linked to surviving plague
A study of the genetic basis of plague immunity in prairie dogs has broad implications for conservation. By comparing whole-genome sequences, the authors identified genetic variants associated with survivorship.
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Study reveals negative consequences of trained immunity in the lungs
Exposure to a common fungal molecule can reprogram immune cells in the lungs, causing them to overreact to infection-like signals and worsen lung damage, according to new research.
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Comprehensive review sheds light on rare blood clotting syndrome linked to COVID-19 vaccines
A new analysis has provided critical insights into the rare but serious condition known as vaccine-induced immune thrombotic thrombocytopenia (VITT). The findings confirm a higher risk of arterial and venous thrombosis after COVID-19 infection compared to vaccination.
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Vanderbilt and Parse Biosciences collaborate on new measles treatment
Vanderbilt University Medical Center and Parse Biosciences, an innovator in single-cell sequencing, are collaborating on a new treatment to help unvaccinated measles victims, as the U.S. measles outbreak has now reached its highest case count in 30 years.
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Cancer-fighting herpes virus shown to be an effective treatment for some advanced melanoma
A genetically engineered herpes simplex virus, when combined with immunotherapy, reduces or eliminates tumors in one-third of clinical trial patients, according to a new study.
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Tiny antibody has big impact on deadly viruses
Researchers have discovered a strategy to neutralise two lethal viruses for which there is currently no approved vaccine or cure. The team identified the first ever nanobody to work against Nipah and Hendra, henipaviruses which have jumped from animals to people.