All Immunology articles – Page 3
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News COVID-19 booster strategies provide lasting immunity
Smaller doses of COVID-19 booster vaccines can provide long-lasting immunity, helping to reduce costs and improve access to vaccination, according to research. The findings could also inform vaccine dosing and options during future pandemics.
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NewsROS–Jak2/Stat3 signaling drives HBV-induced liver inflammation
Scientists investigated the mechanisms underlying HBV-induced liver inflammation and identified a reactive oxygen species (ROS)-dependent signaling cascade that activates the Jak2/Stat3 pathway, thereby triggering hepatic inflammatory responses.
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NewsSweeteners shown to slow growth of important gut bacteria in lab tests
Researchers have shown how commonly-used sweeteners slow the growth of certain gut bacteria. One sweetener in particular – combined with the anti-depressant duloxetine - significantly impaired two important gut bacteria linked to regulating blood sugar and gut health.
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NewsResearchers launch global initiative to study disappearing heritage diets
The world’s ‘heritage’ diets could hold vital clues to better health. Researchers from 12 countries have launched the World Diet Initiative, a global effort to document and study these diets before this knowledge is lost.
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NewsResearch team receives $10 million NIH grant to study how animals fight infection
Researchers have built a collection of living cells from over 100 animal species to explore innate immune diversity. They have received a 5-year, $10 million grant to utilize this ‘cellular zoo’ to determine how diverse animals recognize and fight virus infections.
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NewsMystery of why some toads survive deadly fungus revealed
The mystery of why some populations of amphibians recover following outbreaks of a deadly fungus has been solved in a new study. Researchers looked at peptides that the toads secreted from their skin – a key part of their immune defence.
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NewsResearchers link gut microbe to cancer-fighting immune response
A new study is the first to show metabolites produced by certain bacteria in the gut can positively impact the body’s immune response to cancer.
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NewsEmerging tick-borne virus raises concern
A study shows how a family of tick-borne viruses known as orthonairoviruses can evade immune defenses, offering important insights into emerging infectious disease threats and the potential pandemic risk posed by these viruses.
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NewsGenetically engineered Bifidobacterium shows potential for oral delivery of cancer vaccines
A novel oral vaccine platform using genetically engineered Bifidobacterium could enhance anti-tumor immunity. In an exploratory phase I clinical study, the vaccine was well tolerated and generated immunologic and clinical findings that warrant further investigation.
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NewsNew clues raise hopes for better treatment of RSV in babies
Future therapies for respiratory syncytial virus must target both the virus and its immune response to ensure babies get the best possible outcomes, finds a new study that developed a lab model of baby lungs to show why RSV makes infants so much sicker than adults.
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NewsGut bacteria linked to malnutrition may pass to younger generations
A new study suggests that an intestinal disorder linked to malnutrition and stunted growth may be transmitted from one generation to the next via the small intestinal microbiome.
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NewsGut bacteria boost immune system and help send Vitamin A to T cells
Scientists have discovered that gut bacteria help regulate the development of the body’s immune system by directing the movement of vitamin A through a previously unrecognized cellular network.
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NewsTwo companion papers explain immune ‘exhaustion’ - and how we might prevent it
Chronic and viral infections can literally exhaust certain key cells in the immune system from a constant barrage of attacks. But a new pair of papers has now pointed a way to understand how this exhaustion happens at a molecular level.
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NewsEye problems after COVID-19 can now be explained
Mild COVID-19 can cause severe and long-lasting eye problems, according to a study from Linköping University, Sweden. The study also explains why it has been difficult for sufferers to get help: the abnormal eye behaviour cannot be detected by standard methods. The researchers have developed a diagnostic model to detect ...
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NewsChikungunya fever: Etiology, pathogenesis, and management, with evidence-based application of traditional Chinese medicine
Traditional Chinese medicine (TCM) offers complementary strategies for acute symptoms and chronic polyarthralgia in Chikungunya infection. A review synthesizes current knowledge on etiology, pathogenesis, clinical features, and management.
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NewsCommonly used drugs show small benefit for long Covid fatigue
Over-the-counter antihistamines and a prescription anti-inflammatory drug both have a small benefit in reducing long Covid fatigue among people receiving care from specialist long Covid clinics, according to new findings from a large clinical trial.
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NewsHow immune cells in our gut mesentery fight salmonella
Researchers have found that immune cells in a portion of the abdominal cavity, called the mesentery, play a critical role in suppressing — or exacerbating — salmonella infection.
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NewsMicrobiome and cancer: From passive bystanders to active players
A special issue reviews how microbiome science and cancer biology can converge as an integrated front for precision oncology. Articles span topics from hepatocellular carcinoma and colorectal cancer to gastric cancer and pancreatic ductal adenocarcinoma.
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NewsNew HIV vaccine shows unprecedented success in preclinical study
Scientists have developed an HIV vaccine that trains immune cells to see past HIV’s defenses. This HIV vaccine works by prompting the body’s immune system to make substantial numbers of rarely seen “broadly neutralizing” antibodies.
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NewsHow psychological stress alters gut microbes and ages blood stem cells in mice
Psychological stress is recognized as a risk factor for certain health conditions. Researchers describe a mechanism in mice that explains this association: psychological stress speeds up aging-like changes in the body’s blood-forming stem cells in the bone marrow by altering the intestinal microbiota.