All Immunology articles – Page 3
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NewsMicrobiome insights may help predict immunotherapy benefit in kidney cancer
City of Hope researchers report that gut microbiome composition may influence how patients respond to immunotherapy combinations in metastatic renal cell carcinoma, pointing to a potential biomarker that could help guide treatment selection in the future. The microbiome is a rising focus at City of Hope, highlighted ...
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NewsBrain inflammation is unlikely to explain persistent long COVID symptoms
A new brain imaging study has found no evidence of widespread brain inflammation in patients suffering from prolonged symptoms after COVID-19 infection. Instead, the most severe long COVID symptoms were associated with increased brain activity in regions involved in mood and emotion.
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NewsScientists harness T cells to help the body fight entire viral families
Scientists have discovered that combining key vaccine ingredients could give the body the tools it needs to fight the entire family of arenaviruses with a single vaccine, protecting against life-threatening infections from Lassa virus, Junin virus, and other arenaviruses with pandemic potential.
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NewsLargest-ever Canadian clinical trial tests ‘poop pills’ to improve immunotherapy for lung cancer
For nearly half of people diagnosed with lung cancer, immunotherapy can slow the disease but not stop it. A clinical trial will pair immunotherapy with fecal microbiota transplantation (FMT) with the goal of safely increasing treatment effectiveness. If successful, it could provide new treatment options for people with lung cancer.
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NewsHost-based antifouling gold nanotube sensor for the selective detection of mechanically sensitive serotonin release in intestinal mucosa
A new study report a stretchable electrochemical sensing platform with high deformation insensitivity and strong antibiofouling capability. The platform enables in situ capture of dynamic small-molecule chemical signals in the gut, and revealed a new mechanism underlying enhanced intestinal mechanosensation under microbe-related stimulation.
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NewsHidden small RNA determines if cholera bacterium can infect humans
Scientists have uncovered what gives Vibrio cholerae, the bacterium that causes cholera, the ability to colonize the human gut. They found that a small RNA embedded within another gene controls where cholera thrives, a discovery that could improve prediction and prevention strategies.
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NewsTargeted therapeutics show promise in fighting off drug-resistant bacteria
A new study shows that when under attack, the body’s immune cells activate a cellular process called ‘mitochondrial fission’ to kill invading bacteria. Researchers found an experimental treatment called an HDAC6 inhibitor can re-activate the mitochondrial fission process in immune cells to fight invading bacteria.
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NewsImmune system overreaction linked to deadly flu in pregnancy
Researchers have discovered why influenza can lead to life-threatening complications during pregnancy. In most people, influenza stays in the upper respiratory tract and clears without spreading further. But during pregnancy, the virus can extend into the cardiovascular system, increasing the risk of severe complications for mothers and babies.
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NewsReview highlights antimicrobial peptides as cross-seeding modulators at the neurodegenerative–infectious interface
In a comprehensive review, researchers synthesize emerging evidence that antimicrobial peptides and disease-related amyloids can influence one another through heterotypic cross-seeding interactions.
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NewsBacteria may hold a cancer treatment clue
A review argues that tumors with reproducibly poor prognosis outcomes may share an overlooked feature: bacterial infection within the tumor microenvironment. These bacteria may weaken treatment by altering local immunity, damaging tissue structure, and even inactivating chemotherapeutic drugs.
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NewsInfluenza virus platforms: New hope for vaccines and cancer immunotherapy
Influenza virus is now being engineered to carry foreign genes and reduce virulence, serving not only for next-generation influenza vaccines but also as delivery vectors for heterologous antigens against other infections and cancers, supported by its ability to trigger robust mucosal and systemic immune responses.
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NewsIgG fucosylation linked to severe COVID-19 progression and traditional Chinese medicine therapy
A new study has uncovered that immunoglobulin G (IgG) fucosylation, a critical type of protein glycosylation, is closely associated with the progression of severe COVID-19, offering new insights into disease pathogenesis and potential therapeutic strategies.
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NewsPublic housing mold intervention program reduces asthma-related ED visits
The New York City Housing Authority developed a mold-removal program in response to a 2013 class-action lawsuit filed by residents suffering from asthma due to mold in their apartments. Without Mold Busters, residents would have experienced 25 per cent more asthma-related emergency department (ED) visits.
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NewsFriendly skin bacteria offer hope to beat eczema
Friendly skin bacteria could hold the key to stopping eczema in its tracks, according to researchers. A new study reveals harmless microbes living on our skin release powerful molecules that can shut down the inflammatory chaos triggered by Staphylococcus aureus, the bug long known to wreak havoc in eczema.
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NewsThe liver’s immune cells might be the key to curing hepatitis B
Researchers investigated why some people with chronic hepatitis B infections went off their medications, only for the virus to start to come back — and then some of the patients were cured. It appears a certain type of T cell, some of which coordinate immune responses, spots the infection in the liver and mobilizes an attack.
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NewsAging immune systems show reduced ability to clear tuberculosis during treatment
Immunosenescence increases susceptibility to infectious diseases like tuberculosis (TB) in older adults and hinder effective containment of Mycobacterium tuberculosis during therapeutic intervention.
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NewsCommentary: Dengue viral infection and associated liver disease
A new commentary highlights the time course of serological and liver enzyme elevations in mild versus severe dengue, emphasizes early recognition of progression to acute liver failure, and reviews current vaccination and prevention strategies.
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NewsFDA approves early warning system for sepsis
An early warning system for sepsis, one of the deadliest infections for hospital patients, has been approved for use by the FDA, one of the first AI-based medical tools to get clearance. The tool detects sepsis hours faster than doctors and has reduced deaths by nearly 20%.
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NewsScientists discover ‘hidden switch’ in immune cells that helps the body kill deadly fungus
Scientists have discovered a “control switch” inside our immune cells that helps the body destroy dangerous fungal infections. A protein called RAB5c helps white blood cells kill Aspergillus fumigatus – an airborne fungus that can cause life‑threatening lung infections in people with weakened immune systems.
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NewsWhat the Andes hantavirus outbreak reveals about pandemic risk
The outbreak of Andes hantavirus aboard the international MV Hondius cruise ship underscores how little scientists still know about the viruses circulating silently in wild rodent populations before they spill into humans.