All Immunology articles – Page 11
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NewsA closer look at immune ‘memory’ - and how long it lasts
A new review shares recent advances from the field of immune memory and highlights key steps we might take to develop even more effective, longer-lasting immunity against deadly diseases.
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NewsResearchers uncover how obesity impairs vaccine response
New findings reveal that obesity significantly impaired the quality and longevity of antibody responses to a Pseudomonas aeruginosa vaccine in a mouse model. The impaired antibody production was due to defects in germinal centers.
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NewsTwo research projects to study immune responses to dengue and Zika viruses
Dr. James Earnest, an assistant professor at the Burnett School of Biomedical Sciences, is leading two new research projects to examine how humans build an immune response to dengue and the Zika virus over time, in pursuit of creating better preventative measures.
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NewsSibling stem cell transplant linked to long-term HIV remission
Long-term HIV remission has been achieved in a patient following a stem cell transplant from a sibling carrying a certain genetic mutation, according to new research.
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NewsResearchers explore potential link between COVID-19 and lung cancer risk
New findings have identified a potential association between COVID-19 and increased lung cancer risk, driven by underlying biological mechanisms in the lung. The study integrates human clinical data with mechanistic research in animal and cellular models.
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NewsNanodisc platform improves vaccine design for Ebola, HIV and more
Scientists have created a platform that allows viral surface proteins to be studied in a form that more closely resembles how they appear naturally, utilizing nanodisc technology where these proteins are embedded into particles made of lipid molecules, preserving them in a membrane-like structure.
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NewsTrial assesses safety and effectiveness of two new TB vaccines
Two new vaccines to prevent tuberculosis (TB) are safe for use in adults and children, but they do not offer protection against all forms of TB, finds a large trial from India.
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NewsImmunogenicity and safety of an Escherichia coli-produced 9-valent HPV vaccine in adolescents compared with young women
Based on new findings, the National Medical Products Administration of China has approved a two-dose immunization schedule for the domestically produced 9-valent HPV vaccine in girls aged 9 to 17 years.
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NewsA smarter way to build vaccines: scientists harness AI to target emerging alphaviruses
Scientists have developed a new computational pipeline that could dramatically accelerate the development of vaccines against a group of mosquito-borne viruses known as alphavirus.
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NewsPueraria lobata decoction-derived vesicle-like nanoparticles reveal a novel mechanism for ulcerative colitis treatment
By simulating the traditional decoction process, researchers successfully isolated structurally intact GGD-PDVLNs from dried Pueraria lobata after boiling. These nanoparticles demonstrated remarkable stability in simulated gastric acid and intestinal fluids.
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NewsPhase I study for human monoclonal antibody for Lyme disease demonstrates safety, tolerability, pharmacokinetics
A Phase I clinical trial of a human monoclonal antibody discovered and developed for the prevention of Lyme disease in the U.S. was well tolerated and showed lasting serum concentrations in participants, according to data.
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NewsThree-dimensional microscopy reveals how tick-borne virus replicates
Researchers show how tick‑borne viruses remodel human cells into virus factories, using an advanced microscopy method. The findings provide new insight into how the virus replicates and matures, knowledge that may become important for future treatments against TBE.
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NewsBlood test using artificial intelligence paves the way for early diagnosis of leprosy
A new blood test combined with a standardized questionnaire and artificial intelligence may transform the way leprosy is diagnosed in Brazil. The method showed potential for identifying the disease in its initial stages, when symptoms are subtle and traditional laboratory tests often fail.
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NewsA new mouse model of virus-driven liver cancer may open the door to better diagnosis and treatments
Researchers have created the first mouse model in which chronic viral infection progresses to liver cancer, closely mirroring what happens in people with hepatitis C.
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NewsNovel treatment protocol targets the deadliest cases of C. difficile infection
A new study demonstrated that fecal microbiota transplantation (FMT) can rapidly reverse systemic inflammation and improve survival in patients with fulminant Clostridioides difficile infection.
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NewsHigh‑fat diets linked to rapid decline in protective gut immune cells
In a preclinical study, researchers found that even short-term exposure to high levels of dietary fat results in a quick and selective loss of critical gut immune cells called ILC3s, promoting intestinal permeability and inflammation.
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NewsCharacteristics of CD4+T-cell reduction and pulmonary infections in critically ill immunocompromised patients
A new study investigates the relationship between reduced CD4+T-cell counts and lung infections in immunosuppressed patients admitted to intensive care units (ICUs).
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NewsVanderbilt Center for Antibody Therapeutics signs agreement to develop anti-measles antibody treatment
The Vanderbilt Center for Antibody Therapeutics has signed an option agreement with Saravir Biopharma Inc. for the company to develop human monoclonal antibodies isolated in the laboratory of James Crowe Jr., MD, for the treatment and prevention of measles.
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NewsInterferon therapy found to be well-tolerated in compensated hepatitis B cirrhosis
A multicenter analysis of 920 patients finds no higher risk of serious complications in compensated cirrhosis compared to standard treatment.
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NewsSmall intestinal bacterial overgrowth - and your allergy symptoms
A review suggests that small intestinal bacterial overgrowth (SIBO) may be associated with symptom exacerbation in atopic diseases, such as bronchial asthma, food allergies, or chronic urticaria.