All Immunology articles – Page 12
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NewsResearchers develop mRNA-based vaccine against a deadly plague-causing bacterium
Researchers have used the platform developed for COVID-19 vaccines to create the world’s first mRNA-based vaccine against the deadly, antibiotic-resistant bacterium behind pneumonic plague.
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NewsNew strategy developed to engineer high-affinity receptor-containing antibodies against malaria
Researchers have introduced an innovative approach to developing high-affinity receptor-containing antibodies in vitro, offering a promising strategy to combat malaria.
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NewsPrairie dogs carry genes linked to surviving plague
A study of the genetic basis of plague immunity in prairie dogs has broad implications for conservation. By comparing whole-genome sequences, the authors identified genetic variants associated with survivorship.
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NewsStudy reveals negative consequences of trained immunity in the lungs
Exposure to a common fungal molecule can reprogram immune cells in the lungs, causing them to overreact to infection-like signals and worsen lung damage, according to new research.
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NewsComprehensive review sheds light on rare blood clotting syndrome linked to COVID-19 vaccines
A new analysis has provided critical insights into the rare but serious condition known as vaccine-induced immune thrombotic thrombocytopenia (VITT). The findings confirm a higher risk of arterial and venous thrombosis after COVID-19 infection compared to vaccination.
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NewsVanderbilt and Parse Biosciences collaborate on new measles treatment
Vanderbilt University Medical Center and Parse Biosciences, an innovator in single-cell sequencing, are collaborating on a new treatment to help unvaccinated measles victims, as the U.S. measles outbreak has now reached its highest case count in 30 years.
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NewsCancer-fighting herpes virus shown to be an effective treatment for some advanced melanoma
A genetically engineered herpes simplex virus, when combined with immunotherapy, reduces or eliminates tumors in one-third of clinical trial patients, according to a new study.
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NewsTiny antibody has big impact on deadly viruses
Researchers have discovered a strategy to neutralise two lethal viruses for which there is currently no approved vaccine or cure. The team identified the first ever nanobody to work against Nipah and Hendra, henipaviruses which have jumped from animals to people.
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NewsT cells take aim at Chikungunya virus
A new study offers the first-ever map of which parts of Chikungunya virus trigger the strongest response from the body’s T cells, bringing researchers closer to developing Chikungunya vaccines or therapies that harness T cells to strike specific targets to halt infection.
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NewsImmune responses to friendly skin microbiota could pave way for novel vaccination responses
For her research into how the immune system responds to the beneficial skin microbiome, Djenet Bousbaine is the winner of the 2025 NOSTER & Science Microbiome Prize. Her work reveals a surprisingly sophisticated immune response that could be harnessed for the development of innovative, needle-free vaccination strategies.
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NewsStudy advances understanding of immune system’s crucial role in phage therapy
Scientists have assessed the effectiveness of phage therapy in treating pneumonia. What they discovered about the mechanisms behind phage therapy could inform treatments in clinical settings to help patients facing similarly stubborn infections.
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NewsAntimicrobial common in everyday items linked to allergic conditions in children
Researchers found that children exposed to higher levels of triclosan may be more likely to develop eczema and allergy symptoms.
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NewsThe gut’s secret weapon: viruses that heal
A comprehensive new review reveals how gut viruses interact with gut bacteria and host immunity, highlighting their roles in conditions like inflammatory bowel disease, colorectal cancer, and C. difficile infection. The findings offer a compelling case for harnessing the virome in novel therapies to reshape gut ecology and restore health.
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NewsNew immunotherapy strategy targets difficult-to-treat brain tumors with gut microbiota
Researchers have demonstrated a new therapeutic strategy that can enhance the efficacy of immunotherapy for brain tumors by utilizing gut microbes and their metabolites. This also opens up possibilities for developing microbiome-based immunotherapy supplements in the future.
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NewsNovel flu vaccine adjuvant improves protection against influenza viruses, study finds
Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus challenges when combined with a mucosal adjuvant that enhances the body’s immune response, according to a study.
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NewsStudy links influenza A viral infection to microbiome, brain gene expression changes
Infection with influenza A is found to be associated with disruptions in newborn piglets’ nasal and gut microbiomes and with potentially detrimental changes in gene activity in the hippocampus, a brain structure that plays a central role in learning and memory.
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NewsSupercharged HIV vaccine could offer strong protection with just one dose
Researchers have shown that they can generate a strong immune response to HIV with just one vaccine dose, by adding two powerful adjuvants — materials that help stimulate the immune system.
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NewsImmune ‘dysregulation’ present prior to infection predicts severe responses
A study shows that a common gene signature of immune health or dysfunction predicts severe outcomes from infection, and is present in people with known risk factors such as being a smoker or having a high body mass index, even before they encounter a pathogen.
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NewsImmune tolerance to gut microbes is initiated by a key bacterial sensor
A study has found that the body’s immune “tolerance” to gut microbes depends on an ancient bacterial-sensing protein called STING—normally considered a trigger for inflammation.
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NewsResearchers discover protein necessary for SARS-CoV-2 to evade the body’s defenses
Researchers have identified a protein that plays a key role in helping SARS-CoV-2 hide from the body’s defenses by suppressing the production of viral double-stranded (dsRNA), leading to increased viral replication while limiting the body’s immune response.