All Immunology articles – Page 12
-
NewsTyphoid conjugate vaccine demonstrates strong safety and immunogenicity: Results from Phase 3 study
PATH and EuBiologics Co., LTD have announced Phase 3 results from a clinical trial of a typhoid conjugate vaccine (TCV), EuTYPH-C Inj.® Multi-dose. EuTYPH-C Inj.® Source: CDC/ Armed Forces Institute of Pathology, Charles N. Farmer This photomicrograph reveals some of the histopathology exhibited in a lymph node tissue ...
-
NewsScientists tie lupus to a virus nearly all of us carry
The Epstein-Barr virus is directly responsible for commandeering what starts out as a minuscule number of immune cells to go rogue and persuade far more of their fellow immune cells to launch a widespread assault on the body’s tissues, a study has shown.
-
NewsStudy reveals that flu vaccine performance varies by age
New research comparing four different flu vaccines found that the ability of the vaccines to activate cells of the immune system that help to protect against infection varied greatly depending on the vaccine type and age of the patient.
-
NewsHuman PARP gene could be novel target for viral diseases or immune-mediated disorders
Researchershave discovered a human gene, the protein PARP14, plays a role in regulating interferon, part of the body’s innate immune system. Their study could guide development of antiviral therapies for several groups of viral infection.
-
NewsRepurposed antibiotic shows promise against Central Nervous System Tuberculosis
Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have demonstrated that doxycycline, a commonly available and inexpensive antibiotic, can improve survival rates and neurological outcomes in Central Nervous System Tuberculosis (CNS-TB) in a preclinical non-human study. Published in the Journal of Neuroinflammation, the ...
-
NewsBlood-based immunological signatures for extrapulmonary tuberculosis decoded
Scientists have deciphered the immunological properties of extrapulmonary tuberculosis (EPTB) in the blood of affected patients. The results may help to develop new targeted treatments and tests for this important disease.
-
NewsFlu vaccine providing important protection despite new subclade
Children and adults across England are receiving strong protection from this year’s flu vaccine, despite the emergence of a new subclade driving an unusually early flu season.
-
NewsSingle-cell insights reveal how HPV status reshapes penile tumor immunity
A study found that HPV-positive tumors in penile squamous cell carcinoma cases contained fewer proliferative macrophages and less exhausted CD8+ T cells, along with stronger chemokine signaling, revealing distinct immune remodeling associated with HPV infection.
-
NewsNo-needle test can tell if flu/COVID vaccines are effective
A team of researchers has developed a skin patch that can detect antibodies associated with COVID and flu infections. It’s orders of magnitude more sensitive than existing tests, uses just a half volt of electricity, and can return results in 10 minutes.
-
NewsGut microbiota: implications in pathogenesis and potential therapeutic target in primary biliary cholangitis
A new review synthesizes current evidence on gut microbiota dysbiosis in PBC, elucidates its pathogenic mechanisms, and explores its potential as both a diagnostic biomarker and a novel therapeutic target.
-
NewsHidden HPV-linked cell type may drive early cervical cancer, scientists report
A new study identifies tumor-promoting keratinocytes linked to HPV infection and poor prognosis. Scientists employed single-cell RNA sequencing (scRNA-seq) and multiplex immunohistochemistry (mIHC) to delineate the molecular landscape of early-stage CESC.
-
NewsCOVID-19 vaccination lowers long COVID risk in adolescents
Adolescents who were vaccinated against COVID-19 were less likely to develop long COVID after their first SARS-CoV-2 infection than unvaccinated peers, finds a new study.
-
NewsNew nasal vaccine has potential to transform respiratory disease prevention
Researchers have demonstrated that their nasally-delivered, antibiotic-inactivated Bordetella pertussis (AIBP) vaccine not only prevents severe disease but also curbs bacterial transmission — an achievement long sought by vaccine developers worldwide.
-
NewsERC Synergy Grant awarded to physicist Michael Lässig and virologist Florian Klein
Researchers have been awarded a Synergy Grant by the European Research Council (ERC) for the project CoEvolve, which investigates the co-evolution of viruses and the immune system.
-
NewsTemporary benefit for immune system in early HIV treatment, but dysregulation returns
A study investigated whether immune dysregulation can be prevented by starting HIV medication immediately after infection. Six months after this early treatment, the immune system did indeed work as in people without HIV, but in the longer term, the immune system was disrupted again.
-
NewsNew study links gut microbes to common heart disease - suggesting ‘Jekyll and Hyde’ action
Researchers studying gut microbes recently identified 15 bacterial species associated with coronary artery disease. The analysis reveals multiple pathways linked to disease severity, including increased inflammation and metabolic imbalance.
-
NewsCOVID-19 vaccination linked to reduced infections in children with eczema
Children with atopic dermatitis (AD), commonly known as eczema, may experience fewer infections and allergic complications if they receive the COVID-19 vaccine, according to new research.
-
NewsEarly-stage clinical trial demonstrates promise of intranasal influenza vaccine in generating broad immunity
Researchers report encouraging results from an early phase clinical trial that found an experimental intranasal vaccine triggered a broad immune response against multiple strains of H5N1 ’bird flu’, highlighting the potential of mucosal immunization strategies.
-
NewsAI can speed antibody design to thwart novel viruses: study
Artificial intelligence (AI) and “protein language” models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according to a multi-institutional study
-
NewsNew study finds targets for a new tuberculosis vaccine
A large-scale screen of tuberculosis proteins has revealed several possible antigens that could be developed as a new vaccine for TB, the world’s deadliest infectious disease.