All Immunology articles – Page 15
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NewsNanodisc platform improves vaccine design for Ebola, HIV and more
Scientists have created a platform that allows viral surface proteins to be studied in a form that more closely resembles how they appear naturally, utilizing nanodisc technology where these proteins are embedded into particles made of lipid molecules, preserving them in a membrane-like structure.
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NewsTrial assesses safety and effectiveness of two new TB vaccines
Two new vaccines to prevent tuberculosis (TB) are safe for use in adults and children, but they do not offer protection against all forms of TB, finds a large trial from India.
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NewsImmunogenicity and safety of an Escherichia coli-produced 9-valent HPV vaccine in adolescents compared with young women
Based on new findings, the National Medical Products Administration of China has approved a two-dose immunization schedule for the domestically produced 9-valent HPV vaccine in girls aged 9 to 17 years.
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NewsA smarter way to build vaccines: scientists harness AI to target emerging alphaviruses
Scientists have developed a new computational pipeline that could dramatically accelerate the development of vaccines against a group of mosquito-borne viruses known as alphavirus.
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NewsPueraria lobata decoction-derived vesicle-like nanoparticles reveal a novel mechanism for ulcerative colitis treatment
By simulating the traditional decoction process, researchers successfully isolated structurally intact GGD-PDVLNs from dried Pueraria lobata after boiling. These nanoparticles demonstrated remarkable stability in simulated gastric acid and intestinal fluids.
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NewsPhase I study for human monoclonal antibody for Lyme disease demonstrates safety, tolerability, pharmacokinetics
A Phase I clinical trial of a human monoclonal antibody discovered and developed for the prevention of Lyme disease in the U.S. was well tolerated and showed lasting serum concentrations in participants, according to data.
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NewsThree-dimensional microscopy reveals how tick-borne virus replicates
Researchers show how tick‑borne viruses remodel human cells into virus factories, using an advanced microscopy method. The findings provide new insight into how the virus replicates and matures, knowledge that may become important for future treatments against TBE.
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NewsBlood test using artificial intelligence paves the way for early diagnosis of leprosy
A new blood test combined with a standardized questionnaire and artificial intelligence may transform the way leprosy is diagnosed in Brazil. The method showed potential for identifying the disease in its initial stages, when symptoms are subtle and traditional laboratory tests often fail.
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NewsA new mouse model of virus-driven liver cancer may open the door to better diagnosis and treatments
Researchers have created the first mouse model in which chronic viral infection progresses to liver cancer, closely mirroring what happens in people with hepatitis C.
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NewsNovel treatment protocol targets the deadliest cases of C. difficile infection
A new study demonstrated that fecal microbiota transplantation (FMT) can rapidly reverse systemic inflammation and improve survival in patients with fulminant Clostridioides difficile infection.
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NewsHigh‑fat diets linked to rapid decline in protective gut immune cells
In a preclinical study, researchers found that even short-term exposure to high levels of dietary fat results in a quick and selective loss of critical gut immune cells called ILC3s, promoting intestinal permeability and inflammation.
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NewsCharacteristics of CD4+T-cell reduction and pulmonary infections in critically ill immunocompromised patients
A new study investigates the relationship between reduced CD4+T-cell counts and lung infections in immunosuppressed patients admitted to intensive care units (ICUs).
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NewsVanderbilt Center for Antibody Therapeutics signs agreement to develop anti-measles antibody treatment
The Vanderbilt Center for Antibody Therapeutics has signed an option agreement with Saravir Biopharma Inc. for the company to develop human monoclonal antibodies isolated in the laboratory of James Crowe Jr., MD, for the treatment and prevention of measles.
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NewsInterferon therapy found to be well-tolerated in compensated hepatitis B cirrhosis
A multicenter analysis of 920 patients finds no higher risk of serious complications in compensated cirrhosis compared to standard treatment.
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NewsSmall intestinal bacterial overgrowth - and your allergy symptoms
A review suggests that small intestinal bacterial overgrowth (SIBO) may be associated with symptom exacerbation in atopic diseases, such as bronchial asthma, food allergies, or chronic urticaria.
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NewsDecoding the chemical messengers: Gut microbes talk to the whole body through metabolites
A comprehensive review systematically maps how bacterial metabolites shape immune responses and diseases across organs.
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NewsInequalities in childhood pneumococcal vaccine uptake persist in England despite schedule change
Vaccine uptake data has been examined to assess the impact of moving from a ‘2+1’ to a ‘1+1’ Pneumococcal Conjugate Vaccine (PCV) dose schedule on vaccine coverage and health inequalities among infants in England.
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NewsScientists develop therapeutic, nasally delivered DNA vaccine for tuberculosis
Research shows the vaccine — in combination with drug therapy — accelerated a relapse-free TB cure in mice, improved activity of a drug-resistant TB regimen and stimulated immune responses in nonhuman primates.
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NewsIntroducing environmental microbiota to urban homes shifts the indoor microbiome
Introducing forest soil on an entryway doormat shifted the indoor microbiome of Finnish homes closer to bacterial profiles found outdoors, with less contribution from human-associated bacteria, a new study shows.
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NewsMissing gut bacteria may prevent some people with celiac disease from fully benefiting from high-fiber supplements or diets
Many people with celiac disease are advised to eat more fibre to support digestion and manage symptoms, either through diet or prescribed fibre supplements. New research shows that the benefits of that fibre may depend on whether the right bacteria are present in the gut to break it down.