All Immunology articles – Page 15
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NewsSome antibodies outmaneuver germs from sticking to cells
Researchers have uncovered several new mechanisms by which antibodies block E. coli bacteria that cause urinary tract infections from attaching to bladder cells. Once E. coli bacteria get a strong grip, they can be difficult to flush out.
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NewsRibosomal engineering creates ‘super-probiotic’ bacteria
Using ribosome engineering (RE), researchers introduced mutations affecting the protein synthesis mechanism of probiotic Lacticaseibacillus rhamnosus GG (LGG). These mutant LGGs exhibit altered surface protein expression, including increased presentation of so-called “moonlighting proteins.”
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NewsInternational experts connect infections and aging through cellular senescence
Researchers propose the concept of infection-driven senescence (IDS) to describe the phenomenon in which microbial agents, beyond viruses, can trigger cellular senescence in host cells.
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NewsNew database to target chronic UTIs – a long-overlooked condition that may begin in childhood
A new database targeting chronic urinary tract infections (UTIs) – a long-overlooked condition that may begin in childhood – is set to help researchers uncover why millions of women and girls worldwide suffer from infections that defy treatment and stump microbiologists.
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NewsStudy reveals low immunity against H3N2 strain in Hong Kong; early vaccination urged
Flu activity has surged in many parts of the Northern Hemisphere, driven primarily by a newly emerged H3N2 strain known as ‘subclade K’. Researchers have found that most hospital patients in Hong Kong have little to undetectable levels of neutralising antibodies against this mutated strain.
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NewsOral bacterium tied to disability severity in multiple sclerosis
A research team has conducted a study with findings that suggest a potential association between the relative abundance of Fusobacterium nucleatum (F. nucleatum), a bacterium found in the mouth, and disease severity in multiple sclerosis (MS) patients.
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NewsResearch links tumor bacteria to immunotherapy resistance in head and neck cancer
Two new studies reveal that elevated levels of bacteria in the tumor microenvironment suppress immune response, driving resistance to immunotherapy in patients with head and neck squamous cell carcinoma.
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NewsBeing infected or vaccinated first influences COVID-19 immunity
A new study analysing the immune response to COVID-19 sheds light on an important question: does it matter whether a person was first infected or first vaccinated? According to the results, the order of the events does alter the outcome.
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NewsScientists identify potential therapy and diagnostic markers for cerebral malaria
Researchers examined whether methylene blue could mitigate brain injury during severe malaria, and whether a practical set of blood biomarkers could help clinicians identify cerebral malaria early and track how patients respond to treatment.
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NewsCytomegalovirus breakthrough could lead to new treatments
Researchers have developed a new type of antibody with a modified structure that can outsmart cytomegalovirus and neutralize its ability to evade the immune system.
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NewsThe COVID-19 virus manipulates host cell RNA to shut down the immune system
Researchers have discovered that SARS-CoV-2 uses a sophisticated tactic to evade the human body’s defense system. In addition to evading the immune system before invading the host cell, SARS-CoV-2 manipulates the host cell’s genetic material in a way never before seen in other pathogens.
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NewsYour genes may influence gut microbiome of others, rat study shows
New research, carried out by studying more than four thousand animals, reveals that the composition of the rat gut microbiome is shaped not only by an individual’s own genes but also by the genes of the individuals they share a living space with.
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NewsSilent dengue infections may hold clues to future vaccine design, study finds
Researchers report the first single-cell immune atlas of asymptomatic dengue, offering a rare look at how the immune system can defeat the virus without triggering illness. The work could help guide the design of safer and more effective dengue vaccines.
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NewsStudy reveals high stakes of early immune development—and a potential probiotic fix
Scientists find that certain gut bacteria are essential for building immune defenses during infancy, pointing to new strategies for protecting children’s health. They have identified a way to preserve healthy immune development even when infants need antibiotic treatment.
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NewsCancer-fighting bacterial product ‘cocktails’ may offer personalized treatment
Bacteria may be the next frontier in cancer treatment, according to researchers who devised a new approach of creating bacteria-derived mixtures — or cocktails — to help fight bladder cancer. They found that the cocktails significantly boost the immune system’s ability to fight cancer.
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NewsCan certain bacteria regulate aging of the immune system and its related alterations?
Researchers have discovered a strain of Lentilactobacillus capable of preventing and even reversing aging-related immune alterations. Feeding aged mice with heat-inactivated YRC2606 resulted in lowered levels of inflammatory cytokines and signaling proteins.
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NewsWho is more likely to get long COVID?
Scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.
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NewsA fatal mix-up: How certain gut bacteria drive multiple sclerosis
If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to attack its own nervous system. This mechanism can accelerate the progression of multiple sclerosis.
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NewsResearchers see dramatic drop in HIV-infected immune cells in patient after cancer treatment received
Researchers report they may have taken an early step toward a more practical HIV cure. They focused on a patient undergoing cancer treatment and also living with HIV, who after receiving chemotherapy, had a significant reduction in the number of CD4+ T immune cells that contained an HIV provirus.
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NewsCOVID-19 vaccination significantly reduces risk to pregnant women and baby
Pregnant women who received a COVID-19 vaccine were far less likely to experience severe illness or deliver their babies prematurely, according to a major new study.