All Infectious Disease articles
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New AI tool reveals how drugs kill tuberculosis
A new study offers a powerful AI-assisted method for uncovering exactly how TB drugs kill the bacteria, opening the door to smarter treatment combinations that could work faster.
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Researchers use generative AI to design compounds that can kill drug-resistant bacteria
With help from artificial intelligence, researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).
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A microbial DNA signature differentiates two types of cancer in the liver
Researchers have identified a microbial DNA signature in blood plasma that reliably differentiates primary liver cancer from colorectal cancer that has spread to the liver (metastatic colorectal cancer).
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‘Essentiality’ scan reveals microbe’s ‘must-have’ list
Researchers have spent years taking apart one of the world’s simplest microbes, Mycoplasma pneumoniae, piece by piece, and created a detailed list of what molecular parts the living cell can and cannot do without.
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One universal antiviral to rule them all?
Taking inspiration from a rare mutation that makes people impervious to viral diseases, a researcher is developing a therapy that could bestow this superpower on the rest of us. The mutation causes a deficiency in an immune regulator called ISG15.
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CRISPR-based therapeutics hold potential to combat AMR and cure chronic viral infections, says GlobalData
CRISPR-based therapeutics show potential to combat antimicrobial resistance (AMR) and deliver functional cures for chronic viral infections, says GlobalData, a leading data and analytics company.
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Mount Sinai creates first manual for treating infection-associated chronic illness for clinicians
Mount Sinai has launched the country’s first clinical manual for treating infection-associated chronic illnesses (IACIs). This comprehensive guide, prepared by the Cohen Center for Recovery From Complex Chronic Illnesses, part of the Department of Rehabilitation and Human Performance, will help clinicians better diagnose and care for patients with conditions such ...
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Flu fighters: researchers take a closer look at immune response to influenza
Researchers sought to identify which immune cells in pigs have receptors that are most reactive to influenza. They accomplished this by customizing a technology called single-cell RNA sequencing for pigs to learn more about how a body’s cells operate at a highly detailed level.
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Broad COVID-19 vaccination makes economic sense, especially for older adults, study finds
Vaccinating every person over 65 would actually save the U.S. money, while vaccinating all younger adults would be a reasonable investment, according to a new study.
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Two-dose therapy for S. aureus bloodstream infections on par with standard treatment
A clinical trial has found that the outcome of treating complicated Staphylococcus aureus bloodstream infections with two intravenous (IV) doses of the antibiotic dalbavancin seven days apart is just as good as daily IV doses of conventional antibiotics over four to six weeks.
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Laser therapy enhances treatment of fungus resistant to conventional medication
Researchers have managed to reduce Candida albicans’ resistance to fungicides by incorporating photodynamic inactivation techniques into the treatment. The technology can be used in both human healthcare and the prevention of food contamination.
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Study looks for markers that predict risk of severe chlamydia infection
A new study has identified markers that may predict whether a chlamydia infection is likely to ascend into the uterus and endometrium. The work could lead to new diagnostics that can predict a woman’s risk of severe infection.
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As school returns, so do infections & asthma emergencies. Where kids live can make it worse
A new study highlights how neighborhood conditions shape the seasonal surge of virus-triggered asthma emergencies. It found that children in under-resourced communities face sharply higher rates of asthma flare-ups tied to viral infections during the first weeks of school.
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Bee and frog proteins: nature’s double defense against farm superbugs
A new study reveals that combining natural antimicrobial peptides can significantly slow the development of antimicrobial resistance in bacteria. Using two peptides together prevents harmful bacteria from mutating as quickly, offering a promising alternative to traditional antibiotics.
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Fast, accurate, low-cost diagnostics - and no lab required
Researchers have developed a breakthrough diagnostic tool that could transform how quickly and reliably we detect illnesses like COVID-19, Ebola, AIDS or Lyme disease. The test uses just a single drop of blood, costs a couple of dollars and delivers results in only 15 minutes.
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Seventy-year-old Parkinson’s drug shows promise against tuberculosis
A medication developed in the 1950s to treat Parkinson’s disease may offer a powerful new tool in the fight against tuberculosis. The study found that benztropine can dramatically reduce levels of TB-causing bacteria by boosting the body’s natural immune response.
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Scientists trace the evolution of the H5N1 virus
Researchers have discovered that the currently circulating 2.3.4.4b clade of H5N1 has specific mutations in its genome that increase its human adaptive potential.
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Study: Long COVID remains a substantial financial and medical burden
Individuals with long COVID-19 experienced worse financial and employment outcomes – lasting up to three years after their initial infection. Notably, vaccination against COVID-19 was associated with strikingly improved work and financial outcomes.
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What exactly is Long COVID? It depends who you ask
New research finds that the definition of Long COVID varies so widely across published studies that the percentage of people identified as having the condition can differ dramatically, making it harder to treat patients and advance research.
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Multidrug-resistant bacteria spread from war-zone hospitals to other countries
After Russia’s full-scale invasion, thousands of patients were transferred from Ukraine to other European countries. Researchers in Helsinki found that 8% of Ukrainian refugees had been hospitalised due to war injuries. Almost 80% of them carried multidrug resistant bacteria.