All Vaccinology articles
-
News
HIV vaccines tested in PrEPVacc fail to reduce infections
The results of the PrEPVacc HIV vaccine trial conducted in Eastern and Southern Africa, which ran between 2020 and 2024, show that neither of the two experimental vaccine regimens tested reduced HIV infections among the study population.
-
News
Study identifies unpredicted immune responses to adenoviral COVID vaccines
Researchers have identified unpredicted T-cell immune responses to the adenoviral (Oxford/AstraZeneca and Janssen) COVID-19 vaccines, but not to the mRNA vaccines.
-
News
Study shows promise for a universal influenza vaccine
New research reveals a promising approach to developing a universal influenza vaccine — a so-called “one and done” vaccine that confers lifetime immunity against an evolving virus.
-
News
White paper explores innovative approaches to vaccine trials and pandemic preparedness
An international consortium of experts has created a white paper on innovative approaches for clinical vaccine research in order to be better prepared for future pandemics.
-
News
Scientists ID ‘unconventional’ new pathway for TB vaccines
Marginal zone B (MZB) cells are a natural response to TB infection which has been long overlooked - and which might be a welcome new target.
-
News
Jessica Kahn named Senior Associate Dean for Clinical and Translational Research at Albert Einstein College of Medicine
After an extensive national search, Jessica Kahn, M.D., M.P.H., has been appointed as the senior associate dean for clinical and translational research and director of the Block Institute for Clinical and Translational Research (ICTR) at Albert Einstein College of Medicine. Source: Cincinnati Children’s Hospital Jessica Kahn, M.D., M.P.H., ...
-
News
Nanoparticle vaccines enhance cross-protection against influenza viruses
To offer cross-protection against diverse influenza virus variants, nanoparticle vaccines can produce pivotal cellular and mucosal immune responses that enhance vaccine efficacy and broaden protection, a new study reveals.
-
News
Scientists discover how to improve vaccine responses to potentially deadly bacterium
Researchers have shown in an animal model that targeting a key suppressive immune molecule (IL-10) during the delivery of a vaccine improves the ability of the vaccine to protect against infection.
-
News
Study backs RSV vaccine safety during pregnancy
Vaccinating mothers against respiratory syncytial virus (RSV) during late pregnancy to protect their newborns is not associated with an increased risk of preterm birth or other poor outcomes, according to a new study.
-
News
Researchers reveals why recombinant BCG induces a stronger and longer-lasting response
Researchers are working on a more potent version of the BCG vaccine that protects against TB. While the conventional immunizer reduced infection by 90% in experiments with mice, the recombinant BCG increased protection rates to 99%.
-
Opinion
Cholera: vaccination or better infrastructure?
Vibrio cholerae continues to challenge public health systems worldwide. Should we prioritize vaccination or infrastructure improvements?
-
News
From ‘hit to vial’: Discovery and optimization of a promising vaccine adjuvant
Scientists identified a new and promising adjuvant, dubbed PVP-037 - in principle, this compound can be added to any vaccine to enhance its action.
-
News
Mobile phone data helps track pathogen spread and evolution of superbugs
Combining genomic data and human travel patterns over a 14-year period in South Africa reveals key insights into the spread, evolution and resistance patterns of a major bacterium behind pneumonia and meningitis globally.
-
News
Regular vaccine boosts may help people who are immunocompromised fight Covid-19
New research finds booster doses of bivalent vaccines given every three to six months helps maintain a person’s ability to neutralize multiple SARS-CoV-2 strains, including XBB.1.5.
-
News
SRI is developing a new malaria treatment that aims to protect from the disease
The injectable formulation is affordable, easily administered, and could potentially provide months of protection from the potentially fatal disease.
-
News
A new viral target could help combat the global measles resurgence
A multinational research team has identified a novel way to attack measles, paving the way for new vaccines and antiviral drugs that could help combat the virus’s global resurgence.
-
Features
Infection, immunity and the One Health response in Indonesia
Infectious diseases (IDs) are a major health issue in Indonesia, as in many tropical low- and middle-income countries (LMICs), placing a significant economic burden on limited resources. Vaccination may have a critical role to play in the prevention of zoonotic infectious diseases.
-
News
Imaging measles fusion process reveals pathway to powerful weapon
Scientists have harnessed an imaging technique called cryo-electron microscopy to show—in unprecedented detail—how a powerful antibody can neutralize the measles virus before it completes the process of fusing into the host cell membrane.
-
News
Edited BCG offers potential vaccine to prevent tuberculosis in people of all ages
TB remains the leading cause of death by infectious disease globally, with South Africa having one of the highest incidence rates in the world. Source: Y tambe Apparatus for BCG vaccination - Kuchiki’s needle While the BCG vaccine used to prevent TB is widely available for infants, ...
-
News
Social media use is associated with more frequent vaccination
Researchers have found that more social media use correlates with more vaccination – though the reason for this relationship is different for Democrats and Republicans.