All Vaccinology articles
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Safer, more effective vaccines with new mRNA vaccine technology
A new messenger ribonucleic acid (mRNA) vaccine technology could make future vaccines safer, more effective, and less burdensome for patients. The new approach uses albumin-recruiting lipid nanoparticles to deliver mRNA precisely to lymph nodes while bypassing the liver.
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Scientists research potential anti-ulcer vaccine targeting Helicobacter pylori
Scientists are on the way to finding a vaccine to fight off the Helicobacter pylori bacterium, possibly preventing stomach ulcers and lowering the risk for stomach cancer. They used immunoinformatics to scan its genetic makeup and predict which parts can trigger a strong immune response.
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Measles immunity 90% in BC’s Lower Mainland
In British Columbia’s Lower Mainland, 90% of people have detectable antibodies against measles, indicating high vaccine coverage and population protection, according to a new study.
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Two-dose recombinant shingles vaccine is effective even accounting for prior receipt of live shingles vaccine
A target trial emulation was conducted to assess the effectiveness of recombinant zoster vaccine (RZV) accounting for prior receipt of live zoster vaccine (ZVL) and immunocompetence. The results suggest individuals vaccinated with ZVL should be revaccinated with two doses of RZV.
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Researchers find key to stopping deadly infection
New research has identified a key step that enables rotavirus to infect cells. The researchers found that disabling the process in tissue culture and in mice prevented infection.
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New vaccine shows promise against typhoid and invasive salmonella in first human trial
Researchers have completed a successful Phase 1 clinical trial of a novel vaccine designed to protect against both typhoid fever and invasive non-typhoidal Salmonella–two major causes of illness and death among children in sub-Saharan Africa.
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Breakthrough results from elephant herpesvirus trial find vaccine to be safe
The world’s first vaccine trial against elephant endotheliotropic herpesvirus (EEHV) – a leading cause of death in young Asian elephants – is safe and triggers a strong virus-fighting immune response, according to a research team.
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New herpes virus–based vaccine could cure cancer in the future without side effects
The Herpes simplex virus is a widespread virus that often causes cold sores, and most people carry it. By removing a virulence gene, i.e. a gene that makes the virus harmful to humans, the herpes virus can be repurposed as a cancer vaccine.
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Qdenga vaccine shows effectiveness against dengue under real-world conditions during Brazil’s 2024 outbreak
An international team of researchers has demonstrated that the tetravalent dengue vaccine Qdenga provides significant protection against the disease under real-world conditions, during the large 2024 epidemic in São Paulo, Brazil.
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Under half in US would recommend some routine vaccinations during pregnancy
Data from a new APPC health survey finds a reluctance among the public to recommend that someone who is pregnant get a Covid-19 vaccine, with just 38% saying they would do so. Less than half of the survey respondents (42%) say it is safe to take an mRNA Covid-19 vaccine during pregnancy.
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Risk of long COVID in kids doubles after second infection
Children and adolescents were twice as likely to experience long COVID after catching COVID for the second time, compared to their peers with a single previous infection, results running counter to the popular perceptions that COVID in children is ‘mild’.
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Study shows HPV vaccine protects vaccinated — and unvaccinated — women
A study has found that the introduction of the human papillomavirus (HPV) vaccine in community settings is highly effective in protecting young women from infections caused by the cervical-cancer-causing virus—including women who didn’t even receive the vaccine.
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RSV vaccines safe and effective, Cochrane review finds
A new Cochrane review demonstrates that vaccines for respiratory syncytial virus (RSV) are both safe and effective in protecting vulnerable groups that are most at risk of serious illness, including older adults and infants.
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Meta-analysis: COVID-19 vaccination during pregnancy is safe and beneficial for mother and infant
Vaccination is associated with better neonatal outcomes without added maternal risk, according to research presented during the American Academy of Pediatrics 2025 National Conference & Exhibition.
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Cholera vaccination campaign launched in Darfur to protect over 1.8 million people
A cholera vaccination campaign kicked off on 21 September 2025 in South Darfur, marking the start of a campaign that aims to reach 1.86 million people aged one year and older with oral vaccines in response to the ongoing outbreak.
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New single-dose, temperature-stable rabies vaccines could expand global access
Researchers have discovered a new way to make human rabies vaccines that could greatly expand access to immunization across the globe. The new method creates shots that are temperature-stable—meaning they don’t need to be stored at cold temperatures.
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Tropical diseases: Global health meeting showcases resilience of field under fire
At a moment of monumental challenges for global health, thousands of researchers, clinicians and public health professionals from over 100 countries will gather in Toronto for the 2025 Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).
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Gut punch: $2 million to decode bacteria’s role in fighting disease
A $2 million grant to UC Riverside will explore how gut bacteria shape human health. The NIH award will support Ansel Hsiao’s lab in its quest to answer questions about how gut microbes communicate with each other and with their human hosts to influence health.
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Cattle vaccine immunity ‘boost’ tested by new research
Scientists at Aberystwyth University are leading research into how a widely used vaccine can boost overall immunity in livestock. The four-year study will investigate the concept of ‘trained immunity’ – a form of immune memory triggered by a vaccine.
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NIH grant aims for childhood vaccine against HIV
A multi-institutional team led by Weill Cornell Medicine investigators has been awarded a five-year, $20.8 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, for advanced preclinical development of a promising experimental HIV vaccine. Source: NIAID Transmission electron micrograph ...