All Vaccinology articles
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Scientists awarded $90m to prep for future pandemics from understudied viruses
Scientists are laying the groundwork to rapidly respond to potential future pandemics caused by viruses from five understudied families, developing strategies and tools to produce vaccines and antibody-based therapies.
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Researchers develop promising Lassa fever vaccine
Researchers have developed a promising new vaccine candidate that protects against Lassa fever. The vaccine effectively prevents severe cases of the disease and death in preclinical animal models and paves the way for research in people.
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Calls for more action to support vaccine uptake as new data shows two in three older people prioritise vaccine safety
A new report shows that overall trust in vaccines remains high among 50–70-year-olds but stresses more must be done to reach underserved communities and raise awareness about the risks posed by infectious respiratory illnesses.
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One dose of smallpox vaccine moderately effective in preventing mpox infection
One dose of modified vaccinia Ankara-Bavarian Nordic (MVA-BN) smallpox vaccine is moderately effective in preventing mpox infection and should be made available to communities at risk, finds a new study.
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Scientists close in on mystery of deadly Hep C virus
A new study by a cross-disciplinary research team has identified the protein complex at the surface of the hepatitis C virus that enables it to bind to human cells, opening a pathway to vaccine candidates that can prevent the virus from infecting the cells.
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Study probes prospects of genetically modified live-attenuated leishmania vaccines
A new study discusses genetically modified Leishmania with the potential to confer protection against wild-type Leishmania challenge in animal models.
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Korea University Vaccine Innovation Center teams with Moderna on mRNA-based hantavirus vaccine development
The Vaccine Innovation Center at Korea University College of Medicine has entered into a full-scale collaboration with global pharmaceutical company Moderna to develop an mRNA-based hantavirus vaccine.
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RSV vaccination in older adults with health conditions is cost-effective
Targeting vaccination programs for respiratory syncytial virus (RSV) to older adults with underlying health conditions is a cost-effective way to reduce disease, according to a new modelling study.
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Study uncovers the specialized immune cells that fight COVID-19
A team of researchers from Osaka University has pinpointed the B cells responsible for boosting COVID-19 immunity after vaccination.
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New study provides insight to why Covid vaccines hit some harder than others
Scientists have highlighted factors that may explain why some people perceived more side effects from the SARS-CoV2 vaccine than others, including stress, exercise, and use of hormonal birth control.
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First phase of polio campaign concludes successfully in Gaza
More than 187,000 children under ten years of age were vaccinated with novel oral polio vaccine type 2 (nOPV2) in central Gaza during the first phase of a two-round polio vaccination campaign, conducted between 1–3 September 2024.
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Investigational mpox mRNA vaccine reduces disease severity in primates compared to available vaccines
A new mpox vaccine candidate more effectively limits symptoms and disease duration in primates that were infected with a lethal strain of the mpox virus when compared to a currently licensed modified vaccinia Ankara (MVA) vaccine.
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H5 influenza vaccines: what needs to be done to reduce the risk of a pandemic
As the global threat of H5N1 influenza looms, three international vaccine and public health experts say it is time to fully resource and support a robust strategy to address this and future potential pandemic influenza threats.
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COVID-19 vaccination mandates boosted uptake among health care workers
A new study has found that state-level COVID-19 vaccination mandates successfully increased vaccine rates among health care workers, providing evidence that the policy can boost rates even in a highly vaccinated, highly educated population.
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Gut bacteria composition influences rotavirus vaccine efficacy
Gut microbiota can influence rotavirus vaccine responsiveness and sometimes result in children remaining prone to rotavirus infection and severe disease despite having been vaccinated.
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WHO: Cholera surges as response efforts hit by critical shortage of Oral Cholera Vaccines
Since the start of the year, more than 300,000 cases of cholera and 2,326 deaths have been recorded worldwide, as the World Health Organization warns of a critical shortage of oral vaccines.
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New vaccine against cervical cancer combines prophylactic and therapeutic activity
Scientists at the German Cancer Research Center (DKFZ) have developed a completely new vaccination concept with a new vaccine against cancer-causing human papillomaviruses (HPV).
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WHO declares mpox outbreak a public health emergency of international concern
WHO Director-General Dr Tedros Adhanom Ghebreyesus has declared that the upsurge of mpox in the Democratic Republic of the Congo and a growing number of countries in Africa constitutes a public health emergency of international concern.
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First-of-its-kind vaccine expands malaria protection for pregnant women
For the first time, immunization with a malaria vaccine has been shown to protect mothers from malaria during pregnancy and to protect for two transmission seasons without booster doses of vaccine.
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Study finds shingles increased risk of subsequent cognitive decline
A new study has found that an episode of shingles is associated with about a 20 per cent higher long-term risk of subjective cognitive decline, providing support for getting the shingles vaccine to decrease risk of developing shingles.