All Vaccinology articles – Page 3
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Revealed: New vaccine target to block malaria transmission
Researchers have visualised a key protein complex in malaria parasites for the first time, uncovering a new target for next-generation vaccines that could help stop the disease from spreading.
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Nanoparticles that self-assemble at room temperature could transform vaccine delivery
Researchers have engineered polymer-based nanoparticles that form with a simple temperature shift—no harsh chemicals, no specialized equipment, and no processing needed. They can self-assemble at room temperature and deliver RNA to living cells.
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New farmer-led research project explores how badger vaccination may be used within TB eradication strategy
A progressive new UK project is underway to explore the contribution, effectiveness and practicality of professionally scaled-up, industry delivered badger vaccination as part of a comprehensive TB eradication strategy.
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Study highlights the severity of acute necrotizing encephalopathy in kids with the flu
For a small subset of children, influenza can trigger a rare but serious complication called influenza-associated acute necrotizing encephalopathy (ANE). Now, findings of a multicenter study suggest that ANE is often fatal in these children — despite intensive treatment.
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Mucosal vaccine shows transient action against Covid-19 variant
Mucosal adenovirus vaccine Ad5-XBB.1.5 boosting elicits nasal IgA and transiently prevents JN.1 wave infection for less than 6 months in real-world settings, a new study reveals.
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Why you may get future vaccines via dental floss
Researchers have demonstrated a novel vaccine delivery method in an animal model, using dental floss to introduce vaccine via the tissue between the teeth and gums. It stimulates the production of antibodies in mucosal surfaces, such as the lining of the nose and lungs.
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Studies confirm influence of country of origin on trust in COVID-19 vaccines
During the pandemic, a preference for domestic vaccines or those from countries such as the United States, Germany, and the United Kingdom was observed for the first time. This phenomenon is known in marketing as the country of origin effect.
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New AI tool accelerates mRNA-based treatments for viruses, cancers, genetic disorders
A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various cell types.
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Therapeutic vaccine for chronic hepatitis B enters first clinical trial in patients
TherVacB, a novel therapeutic vaccine for chronic hepatitis B, has entered its first clinical trial in patients. A successful phase 1a trial in healthy volunteers saw the vaccine demonstrate a favorable safety profile and trigger the desired immune responses.
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High-efficacy adjuvanted subunit vaccine against variant infectious bursal disease virus in chicks
Infectious bursal disease (IBD) is an acute, highly contagious disease caused by the infectious bursal disease virus (IBDV), primarily affecting chicks. Notably, the emergence of new mutant strains that exacerbate the disease can cause serious economic losses to the global poultry industry. To date, there is no commercial vaccine against ...
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New study brings vaccine hopes for deadly Nipah virus
Researchers have tested experimental Nipah vaccines in pigs, aiming to cut off the virus at one of its key transmission routes. The study describes the development of three vaccine candidates using different viral surface proteins.
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New jab protects babies from serious lung infection, study shows
Vaccination of pregnant women has been linked to a drop in newborns being admitted to hospital with a serious lung infection, research suggests.
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Vaccination could mitigate climate-driven disruptions to malaria control
Tropical cyclones in Madagascar lead to sharp spikes in malaria infections – particularly in children – due to interruptions in control efforts, according to a new study. However, newly introduced long-lasting vaccines can help to mitigate these gaps.
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Virologists issue warning on rapidly escalating measles crisis in the U.S. and worldwide
The Global Virus Network (GVN) is sounding the alarm over a sharp resurgence of measles cases in the United States and globally. This resurgence, fueled by falling vaccination rates, threatens to erode decades of public health progress.
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Review suggests ending adult boosters for tetanus, diphtheria
The United States could safely drop tetanus and diphtheria booster shots for adults and save an estimated $1 billion a year, according to a new review. The safety and savings depend on maintaining strong childhood vaccination rates, researchers emphasized.
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H5N1 influenza outbreaks in US cattle likely triggered by ‘milk-stealing’ behavior of lactating cows
As of June 2025, H5N1 outbreaks have been reported on more than 1,070 dairy farms across 17 US states. Researchers have solved the mystery of how H5N1 virus enters the mammary glands of dairy cows, and provide a strategy on how to control the disease.
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Aluminum exposure from childhood vaccines not linked to increased risk of autoimmune, allergic, or neurodevelopmental disorders
A nationwide cohort study of Danish children has found no evidence supporting an increased risk for autoimmune, atopic or allergic, and neurodevelopmental disorders associated with exposure to early childhood aluminum-adsorbed vaccines.
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Tiny chip speeds up antibody mapping for faster vaccine design
By analyzing just a drop of blood, this microchip gives researchers quicker-than-ever insight into how a person’s antibodies are interacting with a virus or other pathogen.
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Cohort data from Denmark show real-world evidence of stable protection against HPV-related cervical cancer
Denmark has been offering free vaccination against human papillomavirus (HPV) to girls since 2008. New data show vaccination has effectively reduced infections with cancerogenic HPV 16/18 types covered by the vaccine, indicating population immunity.
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Researchers develop mRNA-based vaccine against a deadly plague-causing bacterium
Researchers have used the platform developed for COVID-19 vaccines to create the world’s first mRNA-based vaccine against the deadly, antibiotic-resistant bacterium behind pneumonic plague.