All Vaccinology articles – Page 3
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Long Reads
Helicobacter pylori, Cancer and AMR
I’ll begin this article with a question that we’ll return to. Do microorganisms exhibit intelligence? Whilst it might not be able to gauge intelligence in single-celled organisms, a certain intelligent behaviour can be perceived. They possess the simplest chemical signalling pathways, yet are sophisticated enough to evade potential harm.
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News
Vaccinated people had lower risk of severe COVID-19 outcomes
Among people who had COVID-19, those who previously received the latest vaccine had a lower risk of having a severe outcome than those who had not, according to new research.
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Breastfeeding after COVID-19 booster can give babies antibodies
Lactating mothers who get the COVID-19 booster pass along the antibodies to their children via their breast milk – and potentially protect babies too young to receive the vaccine.
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Scientists report positive immune response against mpox using a vaccine
Scientists at one of the largest cancer research and treatment organizations in the United States show that its COVID-19 vaccine also protects against mpox.
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Researchers investigate immune response of a man who received 217 Covid vaccinations
Researchers who examined a man who has received more than 200 vaccinations against Covid-19 say there were no negative impacts on his immune system.
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Zika vaccine safe, effective when administered during pregnancy
A vaccine against Zika virus is safe and effective when administered both before and during pregnancy, according to new research.
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IVI to open Africa Regional Office in Rwanda
The International Vaccine Institute (IVI), an international organization with a mission to discover, develop, and deliver safe, effective, and affordable vaccines for global health, and the Ministry of Health of Rwanda have announced that IVI will open its Africa Regional Office in Kigali this year. The IVI ...
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News
BCG mechanism extends protection to beat influenza A
A new study uncovered a previously unknown mechanism that extends the BCG vaccine’s shield to combat influenza A virus—the most prevalent flu strain.
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Fusion protein reveals a conservative antigenic domain across herpesviruses
A new study proposes that the gB DII domain within the herpesvirus family constitutes a broadly conserved neutralizing epitope structural domain.
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COVID vaccine during pregnancy improves neonatal outcomes
A study has found that neonates of booster-vaccinated mothers had less risk of being infected with COVID-19 compared to those of unvaccinated mothers. Neonates of unvaccinated mothers died twice as frequently as those of vaccinated mothers.
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SK bioscience’s typhoid conjugate vaccine achieves WHO prequalification
SK bioscience and the International Vaccine Institute (IVI) announced that the typhoid conjugate vaccine developed by SK bioscience with technology transfer from IVI has achieved the World Health Organization prequalification (PQ).
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Scientists craft enhanced viral structure in VLP vaccines through polymer restructuring
Researchers reported a viromimetic polymer nanoparticle vaccine (VPNVax), crafted by rearranging the RBD proteins of the coronavirus and modifying them onto the surface of pre-assembled polyethylene glycol-polylactic acid polymer nanoparticles.
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PD-1-enhanced DNA vaccine achieves 6-year cART-free AIDS prevention and virologic control
Researchers have found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model.
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Studies find flu vaccines were effective in 2022-2023 flu season
Two recent studies have found that flu vaccines were effective for all ages against both moderate and severe flu in the U.S. during the 2022-2023 flu season.
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High vaccination coverage key against expected increase of measles cases in Europe
In 2023, significant increases in the number of measles cases and outbreaks were observed globally, including in 40 of the 53 countries of the European region, and in at least ten EU/EEA countries.
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Vaccine shows promise against CMV, a virus that causes birth defects
An experimental mRNA vaccine against human cytomegalovirus (CMV), a common virus that can infect babies during pregnancy, elicited some of the most promising immune responses to date of any CMV vaccine candidate, a study reveals.
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Researchers offer new insights into how antibodies function against HSV
Findings from a new study offer insights into how antibodies function in combating herpes simplex virus (HSV) infections. Their research may lead to possible new treatments for neonatal herpes.
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UK urges vaccination as measles surge, man dies in Ireland
The UK government has urged parents to take up the offer of MMR vaccination for their children amid a surge in measles cases. Source: CDC and NIAID Colorized transmission electron micrograph of a measles virus particle (red). Since the last update a week ago, a further 118 ...
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Prior zika infection increases risk of subsequent severe dengue and hospitalization
A study suggests that the mechanism that exacerbates dengue infection following a case of zika differs from that acting on second-time dengue patients. The finding is relevant to the development of a zika vaccine.
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Dengue vaccine protects 79.6% of those vaccinated, study shows
The single-dose Butantan-DV dengue vaccine prevents development of the disease in 79.6% of those vaccinated, according to a new study.