All Vaccinology articles – Page 6
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Biomineralized bacterium acts as in-situ vaccine producer
A new type of bacteria-based autologous cancer vaccine uses calcium carbonate (CaCO3) biomineralized Salmonella (Sal) as an in-situ cancer vaccine producer and systematical ITM regulator.
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Researchers develop a new TB vaccine testing model by leveraging old BCG vaccine
Each year, tuberculosis (TB) kills more people than any other infectious disease, falling out of the top spot only temporarily during the COVID-19 pandemic. Source: Saint Louis University Daniel Hoft, M.D., Ph.D., director of the Saint Louis University Center for Vaccine Development Despite TB’s wide reach and ...
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Infants exposed to certain biologics during pregnancy can safely receive rotavirus vaccine
New research in Canada may prompt a change to vaccination guidelines for infants. Researchers investigated how the immune systems of babies exposed to biologic agent medications during pregnancy are affected.
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Spike in premature births caused by COVID, and halted by vaccines
COVID-19 caused an alarming surge in premature births, but vaccines were key to returning the early birth rate to pre-pandemic levels, according to a new analysis of California birth records.
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Vaccine created to prevent dangerous tropical disease receives FDA approval
The US Food and Drug Administration (FDA) has approved the world’s first vaccine against the chikungunya virus – Ixchiq.
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COVID vaccination before infection strongly linked to reduced risk of developing long covid
Unvaccinated individuals are almost four times as likely to be diagnosed than those vaccinated before first infection, new research shows.
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Scientists boost vaccines with machine learning to drive more effective treatments
Machine learning guided the discovery of new immune pathway-enhancing molecules and found one particular small molecule that could outperform the best immunomodulators on the market.
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Fourth dose of COVID vaccine boosts protection in patients with rheumatic disease
A new study suggests that the recommendation for patients receiving disease-modifying antirheumatic drugs to receive a fourth dose of the mRNA vaccine has saved lives and reduced hospitalizations among patients in this high-risk group.
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Different Covid antibodies target distinct regions of spike protein
Researchers found that Covid antibodies can be categorized into three types, each targeting distinct regions of the viral spike protein, a key component of the vaccine antigen.
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New typhoid conjugate vaccine Bio-TCV® approved in Indonesia
Bio Farma’s Bio-TCV® typhoid conjugate vaccine (TCV) has been licensed in Indonesia following marketing approval from Badan Pengawas Obat dan Makanan (BPOM), the national regulatory authority.
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Live shingles vaccine still protecting 10 years on - despite waning effectiveness
The effectiveness of live zoster (shingles) vaccine is highest in the first year after vaccination and then wanes substantially, but it continues to provide some protection against shingles ten years after vaccination.
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Research partnerships to improve access to vaccines in low and middle-income countries
Four new research hubs that will address challenges of vaccine manufacturing and delivery in developing countries have been announced.
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Learning more about how flu strains evolved may help guide future vaccine development
Researchers studying the evolutionary history of flu viruses have found that a new quantitative analysis of how they evolved may help predict future strains.
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Researchers develop a nasal vaccine that prevents COVID in preclinical studies
New protein-based technology triggers immunity to respiratory pathogens in the airway, before the disease reaches the bloodstream.
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Study supports potential for injectable ‘chemical vaccine’ for malaria using atovaquone
Researchers demonstrate in mouse model that key mutation that renders malaria parasites resistant to atovaquone also makes them non-transmissible via mosquitoes.
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Promising results from E coli-produced HPV vaccine trials in female volunteers
Researchers conducting human trials of an E. coli-produced 9-valent HPV vaccine candidate found it was well tolerated and immunogenic, warranting further efficacy studies in larger populations.
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Study finds increased risk of Guillain-Barré after COVID-19 infection
Having a COVID-19 infection is associated with an increased risk of developing the rare disorder called Guillain-Barré syndrome within the next six weeks.
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Single vaccine protects against three deadly strains of coronavirus
A vaccine designed to protect against three different deadly coronaviruses shows success in mouse studies.
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Researchers unlock power of genetic glycoengineering to advance vaccine tech
A novel glycoengineering platform is poised to revolutionise future production of vaccines and therapeutics to fight infectious diseases.
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Clinical trial finds live vaccinations safe for liver and kidney transplant recipients
Live vaccinations provided to children who previously received liver or kidney transplants were found to be safe and prompted an immune response to guard against several life-threatening conditions.