All Vaccinology articles – Page 4
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Scientists spot an ultra-fast movement on surface of HIV virus
Investigators catch ultra-fast HIV docking mechanism in the act, giving them a new handle on the surface of the virus that could lead to broadly neutralizing antibodies for an AIDS vaccine.
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DNA particles that mimic viruses hold promise as vaccines
Using a DNA-based scaffold carrying viral proteins, researchers created a vaccine that provokes a strong antibody response against SARS-CoV-2.
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Real life data reveals success in controlling respiratory syncytial virus
Early data after passive immunisation with a monoclonal antibody against severe respiratory syncytial virus in 2023 show a decline in hospitalisations and length of stay especially in the most vulnerable group of infants under the age of six months.
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Single dose typhoid conjugate vaccine (TCV) provides lasting efficacy in children
A single dose of the typhoid conjugate vaccine, Typbar TCV®, provides lasting efficacy in preventing typhoid fever in children ages 9 months to 12 years old, according to a new study.
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AiCuris and DZIF sign Collaboration and License Option Agreement
AiCuris Anti-infective Cures AG and the German Center for Infection Research (DZIF) have announced the signing of a collaboration and license option agreement.
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HIV antibodies protect animals in proof-of-concept study
Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people.
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New study to examine very rare adverse events linked to COVID-19 vaccines
A multimillion-dollar global initiative will study causes and risk factors, to ensure safer vaccines are ready for the next potential pandemic.
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Vaccine speeds up the production of antibodies against Covid
A new vaccine uses preexisting immunity to a separate virus (the influenza virus) to help kickstart the process of making antibodies against SARS-CoV-2.
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Research reveals why staph vaccine candidates keep failing - and how to fix the problem
Research from UC San Diego explains the clinical failure of dozens of candidate vaccines for one of the most common human infections; it also suggests a way to fix the problem.
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Priming vaccine tested by global project lays path to HIV vaccine
A global project is attemptng to discover a HIV vaccine based on germline targeting and that is practical for those in Low and Middle-Income Countries.
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COVID-19 vaccine reduces long COVID in children
Researchers have found that vaccination of children provides moderate protection against long COVID. Vaccination also has a stronger effect in adolescents, who have a higher risk of developing long COVID than young children.
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First all-UK study of 67m people reveals consequences of missed COVID-19 vaccines
The first research study of the entire UK population highlights gaps in COVID-19 vaccine coverage. Between a third and a half of the population had not had the recommended number of COVID vaccinations and boosters by summer 2022.
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Resaerchers design thermostable vaccine candidate for SARS-CoV-2 variants
Researchers report the design of a synthetic antigen that can be manufactured as a potential COVID-19 vaccine candidate - it is effective against all current strains of SARS-CoV-2 and can be quickly adapted for future variants as well.
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Smallpox vaccine induces immunity against monkeypox infection in people living with HIV
Researchers have shown that intradermal vaccination with the JYNNEOS vaccine against smallpox is the best option to protect people living with HIV from contracting the monkeypox virus.
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Nasal spray with antibodies could prevent COVID-19
Researchers have shown that nasal drops with IgA antibodies can protect mice from SARS-CoV-2 infection.
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First-in-human vaccine trial for deadly Nipah virus launched
The University of Oxford has launched a new clinical trial to test a vaccine to protect people against deadly Nipah virus. The first clinical trial participants received doses of the ChAdOx1 NipahB vaccine over the last week.
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Sickle cell raises COVID-19 risk, but vaccination lags
Adults with sickle cell disease around half as likely to have had initial doses as people without sickle cell disease, a study in Michigan shows.
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Potential nasal COVID-19 vaccine candidate offers better and longer protection
Study shows that administering a COVID-19 vaccine as a nasal spray rather than a subcutaneous injection enhances the body’s long-term immune memory, thereby increasing the vaccine’s overall effectiveness.
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Valneva vaccinates first participant in pediatric trial of single-shot Chikungunya vaccine
Valneva SE has announced that the first participant has been vaccinated in the Phase 2 clinical trial evaluating the safety and immunogenicity in children of two different dose levels of Valneva’s single-shot chikungunya vaccine.
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Vaccine boosts innate immunity in people with dormant immune cells
Epigenetic cell states predict whether or not an individual profits from the “wake-up call” to the innate immune system that is provided by the BCG vaccine.