All Vaccinology articles – Page 4
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Groundbreaking Ebola vaccination trial launches in Uganda
In a global first, Uganda’s Ministry of Health, the World Health Organization (WHO) and other partners have launched a first ever vaccine trial for Ebola from the Sudan species of the virus, and at an unprecedented speed for a randomized vaccine trial in an emergency. Source: CDC Global ...
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New method offers faster response to new virus variants
Researchers present a promising approach for swift identification of mutations that are crucial for the immune escape that enables the rapid adaptation of vaccines to new virus variants. It is based on a previously established method called mutational scanning.
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WHO and partners enable access to candidate vaccine and treatments for outbreak of Sudan Ebola virus disease in Uganda
WHO and partners have immediately boosted their support to the Ugandan government’s response to an outbreak of Sudan virus disease outbreak (SVD, part of the Ebola family), including by facilitating access to a candidate vaccine and candidate treatments.
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Antibody treatment prevents severe bird flu in monkeys
A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, a new study reports.
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Most Americans favor school vaccination requirements, but support is rising for opt-out options
A new survey finds that nearly three-quarters of U.S. adults support requiring that children be vaccinated against preventable diseases such as measles, mumps, and rubella.
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From Fox News to MSNBC: Diverse media diet linked to higher trust in vaccines
People who get their news from an ideologically diverse array of sources are more likely to get vaccinated, regardless of their political affiliation, new research shows.
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A therapeutic HPV vaccine could eliminate precancerous cervical lesions
A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical lesions, according to the results from a phase II clinical trial.
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Valneva reports high sustained immune response in adolescents one year after Chikungunya Vaccine
Valneva SE, a specialty vaccine company, has reported further positive Phase 3 data in adolescents for its single-shot chikungunya virus (CHIKV) vaccine, IXCHIQ®, which showed a sustained 98.3% sero-response rate one-year after single vaccination.
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Chain reaction: HIV vaccines can lead to antibodies against antibodies
Scientists have discovered that repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus—knowledge that could lead to better vaccines.
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New research provides insight into reduced COVID-19 vaccine efficacy in lupus patients
A recent study provides new insights into why the mRNA vaccines developed to fight COVID-19 in 2021 are less effective in patients with autoimmune diseases, highlighting that lupus patients may require tailored vaccination strategies.
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Hepatitis E vaccination is effective in an epidemic
A case-control study has proved the effectiveness of the two-doses Hecolin vaccine against a potential hepatitis E outbreak.
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Promising COVID-19 vaccine development in animal trials
Researchers developed a COVID-19 vaccine that deploys virus-like particles (VLPs) for immunity stimulation in mice.
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T cells’ capability to fully prevent acute viral infections opens new avenues for vaccine development
Scientists have discovered that T cells—white blood cells that can destroy harmful pathogens—can completely prevent viral infection, to an extent previously thought only possible due to neutralising antibodies.
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Small antibody offers broad protection against influenza
Researchers have discovered an antibody-like molecule that can protect mice from various influenza viruses. The findings could pave the way for new treatments and the development of broader influenza vaccines.
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Self-destructing vaccine offers enhanced protection against tuberculosis in monkeys
A self-destructing vaccine administered intravenously provides additional safety and protection against tuberculosis (TB) in macaque monkeys, suggests new research.
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Virus that threatened humanity opens the future
Researchers have developed an innovative therapeutic platform by mimicking the intricate structures of viruses using artificial intelligence.
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Seasonal flu vaccine study reveals host genetics’ role in vaccine response
Scientists have found that influenza subtype-bias is primarily driven by host genetics, particularly major histocompatibility complex (MHC) class-II polymorphisms, with prior exposure playing a secondary role.
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‘Unbreakable’ Lassa vaccine shows promising results
A live-attenuated vaccine candidate against Lassa virus completely protected guinea pigs exposed to an otherwise lethal dose of the virus, researchers have reported.
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Pediatric investigation study confirms the safety of COVID-19 vaccination during pregnancy
A new study shows that maternal COVID-19 vaccination is not associated with adverse health outcomes in infants.
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Cases of whooping cough growing, but knowledge about it is lacking
Many in the public are not familiar with symptoms of whooping cough. Almost a third of respondents (30%) are not sure if pertussis is the same as whooping cough and not sure (30%) whether a vaccine exists to prevent it.