All Vaccinology articles – Page 5
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COVID-19 vaccine strongly effective for children and adolescents during delta and omicron
Children and adolescents who received one of the main COVID-19 vaccines were significantly protected and showed no increased signs of cardiac complications compared to young people who were not vaccinated.
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WHO prequalifies a second malaria vaccine
WHO has added the R21/Matrix-M malaria vaccine to its list of prequalified vaccines.
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Study reveals clues to how Eastern equine encephalitis virus invades brain cells
An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice.
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Simplified formulation of oral cholera vaccine, licensed by Korean regulatory agency
Euvichol-S, a simplified formulation of oral cholera vaccine, has been licensed by Korean regulatory agency, and is expected to alleviate global cholera vaccine shortages.
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“Honey, I shrunk the cookbook” – new approach to vaccine development
Bioinformaticians have presented a method for identifying epitopes that promise safe immunisation across the broadest possible population group.
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New study explores malaria invasion to help develop life-saving vaccine
An innovative project investigates the progression of malaria infection and the role of the parasite to better aid the development of an effective malaria vaccine and significantly reduce rates of deaths from the disease.
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B cell deficient patients gain protective T cell immunity after SARS-CoV-2 vaccination, infection
Researchers found that vaccinated B cell-deficient individuals had significantly reduced risk of moderate and severe disease in comparison to those who were not vaccinated, despite an absence of anti-spike antibody responses.
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Researchers to develop vaccine candidates against Marburg viruses
The multidisciplinary European consortium MARVAX will receive 7.4 million euros over the next four years for the research and development of vaccines against Marburg viruses.
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Researchers ID opportunities to improve future HIV vaccine candidates
An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study.
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Researchers pave way for next generation COVID-19 immunization strategies
A vaccine booster delivered directly to mucosal site of infection enhances protection against COVID-19 infection in non-human primates, a new study reveals.
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Risk of death reduces after COVID-19 vaccine but protection wanes after six months
The risk of death from COVID-19 decreases significantly after vaccination but this protection diminishes after six months, providing evidence for continued booster doses, a new study has found.
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Mpox vaccine triggers equally strong immune response in smaller doses
Delivering the two-dose mpox vaccine in smaller than the usual FDA-approved doses produced a detectable immune response. This also occurred regardless of whether people were living with or without HIV.
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Researchers develop a novel dry-powder inhaled vaccine platform
Researchers have developed a single-dose, dry-powder, inhalable vaccine platform using nano-micro composite multilevel structures, which is effective in blocking respiratory viral infection and transmission in animal models.
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Researchers develop potential vaccine against antibiotic-resistant enterococci
Researchers have discovered how to create an enterococcal vaccine that is relatively easy to produce and takes advantage of membrane vesicles.
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COVID-19 vaccine candidates show robust boosting potential
Two COVID-19 vaccines have shown strong potential to be an improved approach for boosting immunity to SARS-CoV-2 variants according to interim results of a Phase 1 clinical trial.
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Patients can pause immune-suppressing medicines for COVID-19 booster vaccine
A major clinical trial shows that people with inflammatory conditions are able to improve the antibody response from a COVID-19 booster vaccination by interrupting their treatment for two weeks immediately after having the vaccine.
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Scientists find new, better way to develop vaccines
Researchers have developed a new system to display epitopes in mammal cells for immunization studies and believe that this method can help scientists greatly in immunization efforts.
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First results in using new tools to tackle respiratory syncytial virus
Vaccines for pregnant women and use of monoclonal antibodies have been approved for use in the European Union to prevent respiratory syncytial virus (RSV) among young children. Are those tools working?
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Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses
Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body, and have found a way to prevent ‘off-target’ immune responses.
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Scientists develop needle-free patch vaccine to protect against Zika virus
A simple-to-apply, needle-free vaccine patch has been developed to protect people from the potentially deadly mosquito-borne Zika virus.